Andrew C. Cato - Selected Publications


  1. Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
    Neeb, A.; Figueiredo, I.; Bogdan, D.; Cato, L.; Stober, J.; Jiménez-Vacas, J. M.; Gourain, V.; Lee, I. I.; Seeger, R.; Muhle-Goll, C.; Gurel, B.; Welti, J.; Nava Rodrigues, D.; Rekowski, J.; Qiu, X.; Jiang, Y.; Di Micco, P.; Mateos, B.; Bielskutė, S.; Riisnaes, R.; Ferreira, A.; Miranda, S.; Crespo, M.; Buroni, L.; Ning, J.; Carreira, S.; Bräse, S.; Jung, N.; Gräßle, S.; Swain, A.; Salvatella, X.; Plymate, S. R.; Al-Lazikani, B.; Long, H. W.; Yuan, W.; Brown, M.; Cato, A. C. B.; de Bono, J. S.; Sharp, A.
    2024. Molecular Cancer Therapeutics, 23 (6), 791–808. doi:10.1158/1535-7163.MCT-23-0354
  2. „Mit Trial und Error zum Erfolg“ – KIT Forschungsteam entwickelt neues Medikament gegen hartnäckigen Brust- und Prostatakrebs - Campus-Report am 16.04.2024
    Fuchs, S.; Cato, A. C. B.
    2024. doi:10.5445/IR/1000170061
  3. Development and Validation of a New BAG-1L–Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer
    Neeb, A.; Figueiredo, I.; Gurel, B.; Nava Rodrigues, D.; Rekowski, J.; Riisnaes, R.; Ferreira, A.; Miranda, S.; Crespo, M.; Westaby, D.; de Los Dolores Fenor de La Maza, M.; Guo, C.; Carmichael, J.; Grochot, R.; Tunariu, N.; Cato, A. C. B.; Plymate, S. R.; de Bono, J. S.; Sharp, A.
    2023. Laboratory Investigation, 103 (11), Article no: 100245. doi:10.1016/j.labinv.2023.100245
  4. Identification of an imidazopyridine-based compound as an oral selective estrogen receptor degrader for breast cancer therapy
    Pan, M.; Solozobova, V.; Kuznik, N. C.; Jung, N.; Graessle, S.; Gourain, V.; Heneka, Y. M.; Cramer von Clausbruch, C. A.; Fuhr, O.; Munuganti, R. S. N.; Maddalo, D.; Blattner, C.; Neeb, A.; Sharp, A.; Cato, L.; Weiss, C.; Jeselsohn, R. M.; Orian-Rousseau, V.; Bräse, S.; Cato, A. C. B.
    2023. Cancer Research Communications, 3 (7), 1378–1396. doi:10.1158/2767-9764.CRC-23-0111
  5. A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway
    Kuznik, N. C.; Solozobova, V.; Lee, I. I.; Jung, N.; Yang, L.; Nienhaus, K.; Ntim, E. A.; Rottenberg, J. T.; Muhle-Goll, C.; Kumar, A. R.; Peravali, R.; Gräßle, S.; Gourain, V.; Deville, C.; Cato, L.; Neeb, A.; Dilger, M.; Cramer von Clausbruch, C. A.; Weiss, C.; Kieffer, B.; Nienhaus, G. U.; Brown, M.; Bräse, S.; Cato, A. C. B.
    2022. iScience, 25 (5), Art.Nr. 104175. doi:10.1016/j.isci.2022.104175
  6. Development of a Benzothiazole Scaffold-Based Androgen Receptor N-Terminal Inhibitor for Treating Androgen-Responsive Prostate Cancer
    Kuznik, N. C.; Solozobova, V.; Jung, N.; Gräßle, S.; Lei, Q.; Lewandowski, E. M.; Munuganti, R.; Zoubeidi, A.; Chen, Y.; Bräse, S.; Cato, A. C. B.
    2021. ACS Chemical Biology, 16 (11), 2103–2108. doi:10.1021/acschembio.1c00390
  7. BAG1L: a promising therapeutic target for androgen receptor-dependent prostate cancer
    Lee, I. I.; Kuznik, N. C.; Rottenberg, J. T.; Brown, M.; Cato, A. C. B.
    2019. Journal of molecular endocrinology, 62 (4), R289–R299. doi:10.1530/JME-19-0034
  8. Regulation of the pleiotropic effects of tissue-resident mast cells
    Huber, M.; Cato, A. C. B.; Ainooson, G. K.; Freichel, M.; Tsvilovskyy, V.; Jessberger, R.; Riedlinger, E.; Sommerhoff, C. P.; Bischoff, S. C.
    2019. The journal of allergy and clinical immunology, 144 (4, SI), S31-S45. doi:10.1016/j.jaci.2019.02.004
  9. ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
    Cato, L.; Tribolet-Hardy, J. de; Lee, I.; Rottenberg, J. T.; Coleman, I.; Melchers, D.; Houtman, R.; Xiao, T.; Li, W.; Uo, T.; Sun, S.; Kuznik, N. C.; Göppert, B.; Ozgun, F.; Royen, M. E. van; Houtsmuller, A. B.; Vadhi, R.; Rao, P. K.; Li, L.; Balk, S. P.; Den, R. B.; Trock, B. J.; Karnes, R. J.; Jenkins, R. B.; Klein, E. A.; Davicioni, E.; Gruhl, F. J.; Long, H. W.; Liu, X. S.; Cato, A. C. B.; Lack, N. A.; Nelson, P. S.; Plymate, S. R.; Groner, A. C.; Brown, M.
    2019. Cancer cell, 35 (3), 401–413.e6. doi:10.1016/j.ccell.2019.01.008
  10. Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
    Ainooson, G. K.; Gourain, V.; Stassen, M.; Cato, A. C. B.
    2018. Data in Brief, 20, 1177–1183. doi:10.1016/j.dib.2018.08.188
  11. Tripartite Motif Proteins-A Protein Family Strongly Linked to Cancer
    Elabd, S.; Cato, A. C. B.; Blattner, C.
    2017. Annals of Pharmacology and Pharmaceutics, 2 (10), 1–5
  12. Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer
    Cato, L.; Neeb, A.; Sharp, A.; Buzón, V.; Ficarro, S. B.; Yang, L.; Muhle-Goll, C.; Kuznik, N. C.; Riisnaes, R.; Rodrigues, D. N.; Armant, O.; Gourain, V.; Adelmant, G.; Ntim, E. A.; Westerling, T.; Dolling, D.; Rescigno, P.; Figueiredo, I.; Fauser, F.; Wu, J.; Rottenberg, J. T.; Shatkina, L.; Ester, C.; Luy, B.; Puchta, H.; Troppmair, J.; Jung, N.; Bräse, S.; Strähle, U.; Marto, J. A.; Nienhaus, G. U.; Al-Lazikani, B.; Salvatella, X.; Bono, J. S. de; Cato, A. C. B.; Brown, M.
    2017. eLife, 6, Art.Nr. e27159. doi:10.7554/eLife.27159
  13. An Amyloidogenic Sequence at the N-Terminus of the Androgen Receptor Impacts Polyglutamine Aggregation
    Oppong, E.; Stier, G.; Gaal, M.; Seeger, R.; Stoeck, M.; Delsuc, M.-A.; Cato, A. C. B.; Kieffer, B.
    2017. Biomolecules, 7 (2), 44. doi:10.3390/biom7020044
  14. Polymer pen lithography for biosensing and biomedical applications
    Hirtz, M.; Kumar, R.; Bog, U.; Sekula-Neuner, S.; Liu, H. Y.; Pantel, K.; Cato, A. C. B.; Fuchs, H.
    2016. NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application; Hotel Voronez IBrno; Czech Republic; 19 October 2016 through 21 October 2016, 408–413, TANGER Ltd
  15. Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy
    Polanco, M. J.; Parodi, S.; Piol, D.; Stack, C.; Chivet, M.; Contestabile, A.; Miranda, H. C.; Lievens, P. M.-J.; Espinoza, S.; Jochum, T.; Rocchi, A.; Grunseich, C.; Gainetdinov, R. R.; Cato, A. C. B.; Lieberman, A. P.; La Spada, A. R.; Sambataro, F.; Fischbeck, K. H.; Gozes, I.; Pennuto, M.
    2016. Science translational medicine, 8 (370), 370ra181. doi:10.1126/scitranslmed.aaf9526
  16. Click-Chemistry Based Allergen Arrays Generated by Polymer Pen Lithography for Mast Cell Activation Studies
    Kumar, R.; Bonicelli, A.; Sekula-Neuner, S.; Cato, A. C. B.; Hirtz, M.; Fuchs, H.
    2016. Small, 12 (38), 5330–5338. doi:10.1002/smll.201601623
  17. TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer
    Groner, A.; Cato, L.; Tribolet-Hardy, J. de; Bernasocchi, T.; Janouskova, H.; Melchers, D.; Houtman, R.; Cato, A.; Tschopp, P.; Gu, L.; Corsinotti, A.; Zhong, Q.; Fankhauser, C.; Fritz, C.; Poyet, C.; Wagner, U.; Guo, T.; Aebersold, R.; Garraway, L.; Wild, P. J.; Theurillat, J.-P.; Brown, M.
    2016. Cancer cell, 29 (6), 846–858. doi:10.1016/j.ccell.2016.04.012
  18. Superporous Poly(ethylene glycol) Diacrylate Cryogel with a Defined Elastic Modulus for Prostate Cancer Cell Research
    Göppert, B.; Sollich, T.; Abaffy, P.; Cecilia, A.; Heckmann, J.; Neeb, A.; Bäcker, A.; Baumbach, T.; Gruhl, F. J.; Cato, A. C. B.
    2016. Small, 12 (29), 3985–3994. doi:10.1002/smll.201600683
  19. Abstract 4677: Control of androgen receptor function by the genomic action of the cochaperone Bag-1L
    Cato, L.; Neeb, A.; Adelmant, G.; Ficarro, S.; Westerling, T.; Marto, J. A.; Cato, A. C.; Brown, M.
    2015. Cancer research, 75 (15, Supplement), Art. Nr.: 4677. doi:10.1158/1538-7445.AM2015-4677
  20. Effects of glucocorticoids in the immune system
    Oppong, E.; Cato, A. C. B.
    2015. Advances in experimental medicine and biology, 872, 217–233. doi:10.1007/978-1-4939-2895-8_9
  21. Coregulator Control of Androgen Receptor Action by a Novel Nuclear Receptor-Binding Motif
    Jehle, K.; Cato, L.; Neeb, A.; Muhle-Goll, C.; Jung, N.; Smith, E. W.; Buzon, V.; Carbo, L. R.; Estebanez-Perpina, E.; Schmitz, K.; Fruk, L.; Luy, B.; Chen, Y.; Cox, M. B.; Bräse, S.; Brown, M.; Cato, A. C. B.
    2014. Journal of biological chemistry, 289 (13), 8839–8851. doi:10.1074/jbc.M113.534859
  22. Analysis of the conformation of the androgen receptor in spinal bulbar muscular atrophy by atomic force microscopy
    Jochum, T.; Cato, A. C. B.
    2014. Castoria, G. [Hrsg.] Steoid Receptors : Methods and Protocols New York, N.Y. : Springer Science and Business Media, 2014 (Methods in Molecular Biology ; 1204), 197–204
  23. Splice variant transcripts of the anterior gradient 2 gene as a marker of prostate cancer
    Neeb, A.; Hefele, S.; Bormann, S.; Parson, W.; Adams, F.; Wolf, P.; Miernik, A.; Schoenthaler, M.; Kroenig, M.; Wilhelm, K.; Schultze-Seemann, W.; Nestel, S.; Schaefer, G.; Bu, H.; Klocker, H.; Nazarenko, I.; Cato, A. C. B.
    2014. OncoTarget, 5 (18), 8681–8689. doi:10.18632/oncotarget.2365
  24. Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L
    Cato, L.; Neeb, A.; Brown, M.; Cato, A. C. B.
    2014. Nuclear receptor signaling, 12, e005/1–15. doi:10.1621/nrs.12005
  25. Formation of pathologic oligomers in SBMA
    Jochum, T.; Brinkmann, F.; Ritz, M. E.; Bauer, M.; Moss, D. A.; Cato, A. C. B.
    2014. 22nd Annual Meeting of the Israel Society for Neuroscience (ISFN) and 2nd Binational Italy-Israel Neuroscience Meeting, Eilat, IL, December 14-17, 2013 Journal of Molecular Neuroscience, 53(2014) Suppl.1, (Abstract), 2nd Annual Meeting of the Israel Society for Neuroscience (ISFN) and 2nd Binational Italy-Israel Neuroscience Meeting (2013), Eilat, Israel, December 14–17, 2013
  26. Localization and Dynamics of Glucocorticoid Receptor at the Plasma Membrane of Activated Mast Cells
    Oppong, E.; Hedde, P. N.; Sekula-Neuner, S.; Yang, L.; Brinkmann, F.; Dörlich, R. M.; Hirtz, M.; Fuchs, H.; Nienhaus, G. U.; Cato, A. C. B.
    2014. Small, 10 (10), 1991–1998. doi:10.1002/smll.201303677
  27. Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis
    Bruchmann, A.; Roller, C.; Walther, T. V.; Schäfer, G.; Lehmusvaara, S.; Visakorpi, T.; Klocker, H.; Cato, A. C. B.; Maddalo, D.
    2013. BMC Cancer, 13, 96. doi:10.1186/1471-2407-13-96
  28. Stimulated emission depletion-based raster image correlation spectroscopy reveals biomolecular dynamics in live cells
    Hedde, P. N.; Dörlich, R. M.; Blomley, R.; Gradl, D.; Oppong, E.; Cato, A. C. B.; Nienhaus, G. U.
    2013. Nature Communications, 4, 2093. doi:10.1038/ncomms3093
  29. The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells
    Kullmann, M. K.; Grubbauer, C.; Goetsch, K.; Jäkel, H.; Podmirseg, S. R.; Trockenbacher, A.; Ploner, C.; Cato, A. C. B.; Weiss, C.; Kofler, R.; Hengst, L.
    2013. Cell Cycle, 12, 2625–2635. doi:10.4161/cc.25622
  30. ’SEGRAs’ and beyond
    Cato, A. C. B.
    2013. Molecular and Cellular Endocrinology, 380, 1. doi:10.1016/j.mce.2013.06.011
  31. Molecular mechanisms of glucocorticoid action in mast cells
    Oppong, E.; Flink, N.; Cato, A. C. B.
    2013. Molecular and Cellular Endocrinology, 380, 119–126. doi:10.1016/j.mce.2013.05.014
  32. Membrane localization of glucocorticoid receptor in mast cells activated on allergen arrays
    Sekula-Neuner, S.; Oppong, E.; Hedde, P. N.; Nienhaus, G. U.; Cato, A. C. B.; Fuchs, H.
    2013. International Mastcell and Basophil Meeting, Udine, I, August 28-30, 2013
  33. Enhanced inhibition of prostate tumor growth by dual targeting the androgen receptor and the regulatory subunit type Iα of protein kinase A in vivo
    Eder, I. E.; Egger, M.; Neuwirt, H.; Seifarth, C.; Maddalo, D.; Desiniotis, A.; Schäfer, G.; Puhr, M.; Bektic, J.; Cato, A. C. B.; Klocker, H.
    2013. International Journal of Molecular Sciences, 14, 11942–11962. doi:10.3390/ijms140611942
  34. A potent and selective small molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune deseases
    He, Y.; Liu, S.; Menon, A.; Stanford, S. M.; Oppong, E.; Gunawan, A. M.; Wu, L.; Wu, D. J.; Barrios, A. M.; Bottini, N.; Cato, A. C. B.; Zhang, Z. Y.
    2013. Journal of Medicinal Chemistry, 56, 4990–5008. doi:10.1021/jm400248c
  35. Anterior gradient 2 and 3 - two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells
    Bu, H.; Schweiger, M. R.; Manke, T.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Pasqualini, L.; Shehu, E.; Fuchsberger, C.; Cato, A. C. B.; Klocker, H.
    2013. FEBS Journal, 280, 1249–1266. doi:10.1111/febs.12118
  36. Magnetic heating effect of nanoparticles with different sizes and size distributions
    Müller, R.; Dutz, S.; Neeb, A.; Cato, A. C. B.; Zeisberger, M.
    2013. Journal of Magnetism and Magnetic Materials, 328, 80–85. doi:10.1016/j.jmmm.2012.09.064
  37. A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death
    Maddalo, D.; Neeb, A.; Jehle, K.; Schmitz, K.; Muhle-Goll, C.; Shatkina, L.; Walther, T. V.; Bruchmann, A.; Gopal, S. M.; Wenzel, W.; Ulrich, A. S.; Cato, A. C. B.
    2012. PLoS one, 7 (10), Art.Nr. e45690. doi:10.1371/journal.pone.0045690
  38. Micropatterned surfaces as tools for the study of the rapid non-genomic actions of steroid receptors
    Cato, A. C. B.; Oppong, E.; Sekula-Neuner, S.
    2012. Castoria, G. [Hrsg.] Advances in Rapid Sex-Steroid Action : New Challenges and New Chances in Breast and Prosate Cancers New York, N.Y [u.a.] : Springer Science and Business Media, 2012, 253–266
  39. Knockout of Mkp-1 exacerbates colitis in Il-10-deficient mice
    Matta, R.; Barnard, J. A.; Wancket, L. M.; Yan, J.; Xue, J.; Grieves, J.; Frazier, W. J.; Nelin, L.; Cato, A. C. B.; Liu, Y.
    2012. American Journal of Physiology - Gastrointestinal and Liver Physiology, 302, G1322-G1335. doi:10.1152/ajpgi.00018.2012
  40. The Bcl-2 associated athanogene 5 inhibits stress induces apoptosis and enhances chemoresistance in prostate cancer cells
    Bruchmann, A.; Roller, C.; Walther, T. V.; Cato, A. C. B.; Maddalo, D.
    2012. Molecularly Targeted Therapies: Mechanisms of Resistance, San Diego, Calif., May 9-12, 2012 Clinical Cancer Research, 18(2012) No.10 Suppl., A62 (Abstract). doi:10.1158/1078-0432.MECHRES-A62
  41. What is a name? [Editorial]
    Cato, A. C. B.; Fuller, P. J.
    2012. Molecular and Cellular Endocrinology, 350 (2), 145. doi:10.1016/j.mce.2011.08.011
  42. Allergen arrays for antibody screening and immune cell activation profiling generated by parallel lipid dip-pen nanolithography
    Sekula-Neuner, S.; Maier, J.; Oppong, E.; Cato, A. C. B.; Hirtz, M.; Fuchs, H.
    2012. Small, 8, 585–591. doi:10.1002/smll.201101694
  43. PEST-domain-enriched tyrosine phosphatase and glucocorticoids as regulators of anaphylaxis in mice
    Obiri, D. D.; Flink, N.; Maier, J. V.; Neeb, A.; Maddalo, D.; Thiele, W.; Menon, A.; Stassen, M.; Kulkarni, R. A.; Garabedian, M. J.; Barrios, A. M.; Cato, A. C. B.
    2012. Allergy, 67, 175–182. doi:10.1111/j.1398-9995.2011.02731.x
  44. Toxic and non-toxic aggregates from the SBMA and normal forms of androgen receptor have distinct oligomeric structures
    Jochum, T.; Ritz, M. E.; Schuster, C.; Funderburk, S. F.; Jehle, K.; Schmitz, K.; Brinkmann, F.; Hirtz, M.; Moss, D.; Cato, A. C. B.
    2012. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1822, 1070–1078. doi:10.1016/j.bbadis.2012.02.006
  45. Bag-1 proteins inhibit prostate cancer cell growth through a distinct sequence that binds the glucose regulated protein GRP78
    Maddalo, D.; Neeb, A.; Jehle, K.; Schmitz, K.; Walther, T.; Shatkina, L.; Muhle-Goll, C.; Gopal, S. M.; Wenzel, W.; Ulrich, A. S.; Cato, A. C. B.
    2011. 3rd Internat.Meeting on Cell Stress and Apoptosis - to Arturo, Salerno, I, June 23-25, 2011
  46. Dip-pen nanolithography and TIRF microscopy as tools for the study of the localisation and dynamic behaviour of the GR at the plasma membrane of mast cells
    Oppong, E.; Hedde, N.; Sekula-Neuner, S.; Fuchs, H.; Nienhaus, G. U.; Cato, A. C. B.
    2011. Nuclear Receptors : From Molecular Mechanism to Health and Disease, EMBO Meeting, Sitges, E, September 16-20, 2011
  47. Steroid hormones regulation of metastasis-associated chaperone proteins agr2 and agr3 in prostate cancer cells
    Bu, H.; Schweiger, M.; Fuchsberger, C.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Manke, T.; Cato, A. C. B.; Klocker, H.
    2011. 26th Annual Congress of the European Association of Urology, Wien, A, March 18-22, 2011 European Urology Supplements, 10(2011) (Abstract)
  48. Steroid hormones regulation of metastasis-associated chaperone proteins agr2 and agr3 in prostate cancer cells
    Bu, H.; Schweiger, M.; Fuchsberger, C.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Manke, T.; Cato, A. C. B.; Klocker, H.
    2011. European urology / Supplements, 26th Annual Congress of the European Association of Urology, Wien, A, March 18-22, 2011, (Abstract), 10, 264–265
  49. Pro-apoptotic properties of Bag-1 peptides in the control of prostate cancer cell growth
    Maddalo, D.; Neeb, A.; Jehle, K.; Schmitz, K.; Shatkina, L.; Muhle-Goll, C.; Gopal, S. M.; Wenzel, W.; Ulrich, A. S.; Cato, A. C. B.
    2011. 102nd Annual Meeting of the American Association for Cancer Research (AACR), Orlando, Fla., April 2-6, 2011 Cancer Research, 71(2011) Nr.8, Suppl.1 Abstract 5403
  50. The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection
    Bu, H.; Bormann, S.; Schäfer, G.; Horninger, W.; Massoner, P.; Neeb, A.; Lakshmanan, V. K.; Maddalo, D.; Nestl, A.; Sültmann, H.; Cato, A. C. B.; Klocker, H.
    2011. The Prostate, 71, 575–587. doi:10.1002/pros.21273
  51. Depletion of the cellular levels of Bag-1 proteins attenuates phorbol ester-induced downregulation of IκBα and nuclear accumulation of NF-κB
    Maier, J. V.; Volz, Y.; Berger, C.; Schneider, S.; Cato, A. C. B.
    2010. Biochemical and Biophysical Research Communications, 401, 406–11. doi:10.1016/j.bbrc.2010.09.067
  52. Cross-talk between the p38α and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation
    Staples, C. J.; Owens, D. M.; Maier, J. V.; Cato, A. C. B.; Keyse, S. M.
    2010. Journal of Biological Chemistry, 285, 25928–25940. doi:10.1074/jbc.M110.117911
  53. Mast cell activation on allergen arrays prepared by lipid dip-pen nanolithography
    Sekula-Neuner, S.; Maier, J.; Obiri, D.; Cato, A. C. B.; Fuchs, H.
    2010. Bioactive Lipids: Biochemistry and Diseases, Keystone Symp.on Molecular and Cellular Biology, Kyoto, J, June 6-11, 2010
  54. Specific N-terminal mutations in the human androgen receptor induce cytotoxicity
    Funderburk, S. F.; Shatkina, L.; Mink, S.; Weis, Q.; Weg-Remers, S.; Cato, A. C. B.
    2009. Neurobiology of Aging, 30, 1851–64. doi:10.1016/j.neurobiolaging.2007.12.023
  55. Increased inflammation, impaired bacterial clearance, and metabolic disruption after Gram-negative sepsis in Mkp-1-deficient mice
    Frazier, J.; Wang, X.; Wancket, L. M.; Li, X. A.; Meng, X.; Nelin, L. D.; Cato, A. C. B.; Liu, Y.
    2009. Journal of Immunology, 183, 7411–19. doi:10.4049/jimmunol.0804343
  56. Protein templating and cell culture on lipid nanoarrays
    Sekula-Neuner, S.; Fuchs, J.; Weg-Remers, S.; Ellmark, P.; Borrebaeck, C. A. K.; Siebenbrock, J.; Seibold, P.; Schunck, T.; Fischer, R.; Maier, J.; Cato, A. C.; Engin, S.; Wedlich, D.; Welle, A.; Fuchs, H.; Lenhert, S.
    2009. CFN Summer School on Nano-Biology, Bad Herrenalb, September 8-11, 2009
  57. Regulation of hAG-2 and hAG-3 transcripts inprostate cancer
    Bu, H.; Seifarth, C.; Schäfer, G.; Cato, A. C. B.; Klocker, H.
    2008. 32nd FEBS Congress, Wien, A, July 7-12,2007 FEBS Journal, 274(2007) Suppl.1, (Abstract)
  58. The glucocorticoid receptor controls hepatic dyslipidemia through Hes1
    Lemke, U.; Krones-Herzig, A.; Diaz, M. B.; Narvekar, P.; Ziegler, A.; Vegiopoulos, A.; Cato, A. C. B.; Bohl, S.; Klingmüller, U.; Screaton, R. A.; Müller-Decker, K.; Kersten, S.; Herzig, S.
    2008. Cell Metabolism, 8, 212–23. doi:10.1016/j.cmet.2008.08.001
  59. Regulation of hAG-2 and hAG-3 transcripts inprostate cancer
    Bu, H.; Seifarth, C.; Schäfer, G.; Cato, A. C. B.; Klocker, H.
    2007. The FEBS journal, 274, 173. doi:10.1111/j.0014-2956.2007.05861_3.x
  60. Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation
    Horsch, K.; Wet, H. de; Schuurmans, M. M.; Allie-Reid, F.; Cato, A. C. B.; Cunningham, J.; Burrin, J. M.; Hough, F. S.; Hulley, P. A.
    2007. Molecular Endocrinology, 21, 2929–40. doi:10.1210/me.2007-0153
  61. Dual specificity phosphatase 1 knockout mice show enhanced susceptibility to anaphylaxis but are sensitive to glucocorticoids
    Maier, J. V.; Brema, S.; Tuckermann, J.; Herzer, U.; Klein, M.; Stassen, M.; Moorthy, A.; Cato, A. C. B.
    2007. Molecular Endocrinology, 21, 2663–71. doi:10.1210/me.2007-0067
  62. Overexpression and gene amplification of BAG-IL in hormone-refractory prostate cancer
    Mäki, H. E.; Saramäki, O. R.; Shatkina, L.; Martikainen, P. M.; Tammela, T. L. J.; Weerden, W. M. van; Vessella, R. L.; Cato, A. C. B.; Visakorpi, T.
    2007. Journal of Pathology, 212, 395–401. doi:10.1002/path.2186
  63. Nuclear hormome receptors: regulators of gene transcription and cellular signalling
    Cato, A. C. B.; Shatkina, L.
    2007. Ganten, D. [Hrsg.] Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine Berlin [u.a.] : Springer, 2006, 1314–20
  64. Light-inducible and clock-controlled expression of MAP kinase phosphatase 1 in mouse central pacemaker neurons
    Doi, M.; Cho, S.; Yujnovsky, I.; Hirayama, J.; Cermakian, N.; Cato, A. C. B.; Sassone-Corsi, P.
    2007. Journal of Biological Rhythms, 22, 127–39. doi:10.1177/0748730406298332
  65. Androgen receptor, polyglutamine stretch amplification and motor neuropathy
    Cato, A. C. B.
    2007. Androgens 2006, Cambridge, GB, September 25-27, 2007
  66. SBMA pathology and phosphorylation of the androgen receptor
    Funderburk, S.; Shatkina, L.; Mink, S.; Weis, Q.; Cato, A. C. B.
    2007. Neurodegenerative Diseases : Molecular Mechanisms in a Functional Genomics Framework, Berlin, September 6-9, 2006
  67. Glucocorticoid receptor: an integrator of multiple signal transduction pathways and diverse physiological processes
    Cato, A. C. B.
    2007. Omics Informatics Symp., Tokyo, J, March 20-21, 2006
  68. Ultra-sensitive detection of proteins by a bio-barcode nanoparticle approach using a micro-magnetic reactor
    Schneider, S.; Eberhardt, P.; Herzer, U.; Theilacker, N.; Berensmeier, S.; Rogge, T.; Weiß, C.; Cato, A. C. B.
    2006. 2nd FRONTIERS Annual Meeting, Acireale, I, October 24-26, 2006
  69. Aplidin induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation
    Gonzalez-Santiago, L.; Suarez, Y.; Zarich, N.; Munoz-Alonso, M. J.; Cuadrado, A.; Tormo, T.; Maier, J. V.; Moorthy, A.; Cato, A. C. B.; Rojas, J. M.; Munoz, A.
    2006. Cell Death and Differentiation, 13, 1968–81. doi:10.1038/sj.cdd.4401898
  70. Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index
    Schäcke, H.; Rehwinkel, H.; Asadullah, K.; Cato, A. C. B.
    2006. Experimental Dermatology, 15, 565–73. doi:10.1111/j.1600-0625.2006.00453.x
  71. Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer
    Zhang, C. W.; Kolb, A.; Büchler, P.; Cato, A. C. B.; Mattern, J.; Rittgen, W.; Edler, L.; Debatin, K. M.; Büchler, M. W.; Friess, H.; Herr, I.
    2006. BMC Cancer, 6, 61. doi:10.1186/1471-2407-6-61
  72. Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock
    Hammer, M.; Mages, J.; Dietrich, H.; Servatius, A.; Howells, N.; Cato, A. C. B.; Lang, R.
    2006. Journal of Experimental Medicine, 203, 15–20. doi:10.1084/jem.20051753
  73. Androgen receptor
    Cato, A. C. B.
    2005. European Congress of Endocrinology, Göteborg, S, September 3-7, 2005
  74. SBMA pathology and phosphorylation of the androgen receptor
    Funderburk, S.; Shatkina, L.; Weis, Q.; Huber, A.; Cato, A. C. B.
    2005. 2nd Meeting on Molecular Mechanisms of Neurodegeneration, Milano, I, May 7-10, 2005
  75. Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens
    Whitaker, H. C.; Hanrahan, S.; Totty, N.; Gamble, S. C.; Waxman, J.; Cato, A. C. B.; Hurst, H. C.; Bevan, C. L.
    2004. Clinical Cancer Research, 10, 7392–7401
  76. The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy
    Cato, A. C. B.; Schäcke, H.; Sterry, W.; Asadullah, K.
    2004. Current Drug Targets - Inflammation & Allergy, 3, 345–51
  77. Molecular chaperones and cochaperones as regulators of the nuclear action of steroid receptors
    Cato, A. C. B.
    2004. Graduate College 340 - Methods to Determine the Structure of Proteins and Cellular Components, Hirschegg, A, September 11-18, 2004
  78. Polyglutamine stretch amplification in androgen receptor and neurotoxicity: lessons from Drosophila melanogaster
    Cato, A. C. B.
    2004. Symp.on Androgen Receptor Function (Androgen 2004), Berlin, October 7-8, 2004
  79. Glucocorticoids synergize with IL-1ß to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells
    Sakai, A.; Han, J. H.; Cato, A. C. B.; Akira, S.; Li, J. D.
    2004. BMC Molecular Biology, 2, 5. doi:10.1186/1471-2199-5-2
  80. The androgen receptor: molecular biology
    Klocker, H.; Gromoll, J.; Cato, A. C. B.
    2004. Nieschlag, E. [Hrsg.] Testosterone : Action, Deficiency, Substitution Cambridge : Cambridge Univ.Press, 2004
  81. Androgen receptor cross-talk and implications for intersex phenotype
    Cato, A. C. B.
    2004. Intersex - from Gene to Gender, Lübeck, April 1-3, 2004
  82. The cochaperone Bag-1 as a ligand activated repressor of glucocorticoid receptor action
    Hong, W.; Herzer, U.; Martin, E.; Cato, A. C. B.
    2004. 16th Internat.Symp.of the Journal of Steroid Biochemistry and Molecular Biology, Seefeld, A, June 5-8, 2004
  83. Non-classical signaling and cross-talk of androgen receptor
    Cato, A. C. B.
    2004. 6th European Federation of Endocrine Societies Postgraduate Course in Molecular and Cellular Endocrinology, Berlin, June 27-29, 2003 7th European Federation of Endocrine Societies Postgraduate Course in Molecular and Cellular Endocrinology, Berlin, October 3-5, 2004
  84. Membrane localization and rapid non-transcriptional action of the androgen receptor
    Mink, S.; Shatkina, L.; Nestl, A.; Cato, A. C. B.
    2004. Watson, C.S. [Hrsg.] The Identities of Membrane Steroid Receptors :. and Other Proteins Mediating Nongenomic Steroid Action Dordrecht : Kluwer Acad.Publ., 2003, 111–17
  85. The Cochaperone Bag-1L enhances androgen receptor action via interaction with the NH₂-terminal region of the receptor
    Shatkina, L.; Mink, S.; Rogatsch, H.; Klocker, H.; Langer, G.; Nestl, A.; Cato, A. C. B.
    2003. Molecular and Cellular Biology, 23, 7189–97. doi:10.1128/MCB.23.20.7189-7197.2003
  86. Rapid signaling and cross-talk by androgen receptor
    Cato, A. C. B.
    2003. 3rd Internat.Meeting on Rapid Responses to Steroid Hormones, Firenze, I, September 12-14, 2003
  87. Attenuation of IgE-receptor signalling in mast cells as a molecular basis for the antiallergic action of glucocorticoids
    Sancono, A.; Kassel, O.; Maier, J.; Hesslinger, C.; Cato, A. C. B.
    2003. 1st ERS Lung Science Conf., Taormina, I, March 28-30, 2003 FEBS Young Scientist Forum, Bruxelles, B, July 1-3, 2003 European Respiratory Journal, 22(2003) Suppl., S-41S
  88. Attenuation of IgE-receptor signalling in mast cells as a molecular basis for the antiallergic action of glucocorticoids
    Sancono, A.; Kassel, O.; Maier, J.; Hesslinger, C.; Cato, A. C. B.
    2003. European Respiratory Journal, 1st ERS Lung Science Conf., Taormina, I, March 28-30, 2003 FEBS Young Scientist Forum, Bruxelles, B, July 1-3, 2003, Suppl., S-41S, 22, 40
  89. Inhibition of p38 MAPK by glucocorticoid via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of Toll-like receptor 2
    Imasato, A.; Desbois-Mouthon, C.; Han, J.; Kai, H.; Cato, A. C. B.; Akira, S.; Li, J. D.
    2003. Journal of Biological Chemistry, (2002), 277, 47444–50
  90. Mast cells as targets for glucocorticoids in the treatment of allergic disorders
    Kassel, O.; Cato, A. C. B.
    2002. Cato, A.C.B. [Hrsg.] Recent Advances in Glucocorticoid Receptor Action Berlin [u.a.] : Springer, 2002 (Ernst Schering Research Foundation Workshop ; 40), 153–76
  91. Regulation of androgen receptor action by a chaperone-cochaperone complex, composed of BAG-1L and HSP70
    Shatkina, L.; Mink, S.; Langer, G.; Cato, A. C. B.
    2002. Symp.on Androgen Receptor Function, Groot Begijnhof, Leuven, B, September 13-14, 2002
  92. Functional analysis of human androgen receptor with a polyglutamine stretch amplification
    Korali, Z.; Weih, D.; Zinke, I.; Abert, S.; Huber, A.; Paulsen, R.; Cato, A. C. B.
    2002. 2nd European Congress of Andrology, Malmö, S, September 19-22, 2002
  93. Rapid actions of steroid receptors in cellular signaling pathways
    Cato, A. C. B.; Nestl, A.; Mink, S.
    2002. Science, ’s STKE Signal Transduction Knowledge Environment, (2002) Issue 138, re9
  94. Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase
    Shuto, T.; Imasato, A.; Jono, H.; Sakai, A.; Xu, H.; Watanabe, T.; Rixter, D. D.; Kai, H.; Andalibi, A.; Linthicum, F.; Guan, Y. L.; Han, J.; Cato, A. C. B.; Lim, D. J.; Akira, S.; Li, J. D.
    2002. Journal of Biological Chemistry, 277, 17263–70
  95. Warum scheitert die Antihormontherapie bei fortgeschrittenem Prostatakrebs?
    Cato, A. C. B.; Shatkina, L.; Nestl, A.; Mink, S.
    2002. Nachrichten - Forschungszentrum Karlsruhe, 34, 41–48
  96. The amino terminus of the human AR is target for corepressor action and antihormone agonism
    Dotzlaw, H.; Moehren, U.; Mink, S.; Cato, A. C. B.; Iniguez Lluhi, J. A.; Baniahmad, A.
    2002. Molecular Endocrinology, 16, 661–73
  97. Dichotomy of glucocorticoid action in the immune system
    Asadullah, K.; Schäcke, H.; Cato, A. C. B.
    2002. Trends in immunology, 23 (3), 120–122. doi:10.1016/S1471-4906(01)02147-0
  98. Interdigital apoptosis and downregulation of BAG-1 expression in mouse autopods
    Crocoll, A.; Herzer, U.; Ghyselinck, N. B.; Chambon, P.; Cato, A. C. B.
    2002. Mechanisms of development, 111 (1-2), 149–152. doi:10.1016/S0925-4773(01)00598-6
  99. Glucocorticoids inhibit MAP-kinase via increased expression and decreased degradation of MKP-1
    Kassel, O.; Sancono, A.; Krätzschmar, J.; Kreft, B.; Cato, A. C. B.
    2002. Keystone Symp.’Protein Phosphorylation and Mechanisms of Cellular Regulation (X2)’, Taos, N.M., March 5-10, 2002
  100. A Drosophila model for the functional analysis of human androgen receptor with a polyglutamine stretch amplification
    Korali, Z.; Weih, D.; Abert, S.; Mink, S.; Huber, A.; Paulsen, R.; Zinke, I.; Pankratz, M. J.; Cato, A. C. B.
    2002. Keystone Symp.’Nuclear Receptor Superfamily (D4)’, Snowbird, Utah, April 13-19, 2002
  101. BAG-1 family of cochaperones in the modulation of nuclear receptor action
    Cato, A. C. B.; Mink, S.
    2002. Journal of Steroid Biochemistry and Molecular Biology, (2001), 78, 379–88
  102. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
    Kassel, O.; Sancono, A.; Krätzschmar, J.; Kreft, B.; Stassen, M.; Cato, A. C. B.
    2001. The EMBO Journal, (2001), 20 (24), 7108–7116. doi:10.1093/emboj/20.24.7108
  103. A Drosophila model for spinal and bulbar muscular atrophy
    Korali, Z.; Weih, D.; Mink, S.; Huber, A.; Paulsen, R.; Zinke, I.; Pankratz, M. J.; Cato, A. C. B.
    2001. Nuclear Receptors in Health and Disease, Mont Saint Odile, F, September 14-17, 2001
  104. BAG-1 family of cochaperones in the modulation of nuclear receptor action
    Crocoll, A.; Mink, S.; Hübner, S.; Schneikert, J.; Cato, A. C. B.
    2001. Current Topics in Steroid Research, 3, 53–62
  105. Modulation of glucocorticoid- and androgen receptor action by Bag-1 cochaperones
    Mink, S.; Schneikert, J.; Hong, W.; Shatkina, L.; Cato, A. C. B.
    2001. Euro Conf.and EMBO Workshop, Sant Feliu de Guixols, E, May 26-31, 2001
  106. Alteration of the stability of Bag-1 protein in the control of olfactory neuronal apoptosis
    Sourisseau, T.; Desbois, C.; Debure, L.; Bowtell, D. D. L.; Cato, A. C. B.; Schneikert, J.; Moyse, E.; Michel, D.
    2001. Journal of Cell Science, 114, 1409–16
  107. Expression level-dependent contribution of glucocorticoid receptor domains for functional interaction with STAT5
    Doppler, W.; Windegger, M.; Soratroi, C.; Tomasi, J.; Lechner, J.; Rusconi, S.; Cato, A. C. B.; Almlöf, T.; Liden, J.; Okret, S.; Gustafson, J. A.; Richard-Foy, H.; Starr, D. B.; Klocker, H.; Edwards, D.; Geymayer, S.
    2001. Molecular and Cellular Biology, 21, 3266–79
  108. Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor
    Schneikert, J.; Hübner, S.; Langer, G.; Petri, T.; Jäättelä, M.; Reed, J.; Cato, A. C. B.
    2000. The EMBO Journal, 19, 6508–16
  109. Modulation of androgen receptor action
    Shatkina, L.; Mink, S.; Becker, M.; Cato, A. C. B.
    2000. Symp.on Androgen Receptor Function - Androgens 2000, Rotterdam, NL, September 22-23, 2000
  110. BAG-1M: a potential specificity determinant of corticosteroid receptor action
    Crocoll, A.; Schneikert, J.; Hübner, S.; Martin, E.; Cato, A. C. B.
    2000. Kidney International, 57, 1265–69
  111. Isoform-specific expression of BAG-1 in mouse development
    Crocoll, A.; Blum, M.; Cato, A. C. B.
    2000. Mechanisms of Development, 91, 355–59
  112. Cytoplasmic localization and the choice of ligand determine aggregate formation by androgen receptor with amplified polyglutamine stretch
    Becker, M.; Martin, E.; Schneikert, J.; Krug, H. F.; Cato, A. C. B.
    2000. The Journal of Cell Biology, 149, 255–62
  113. How to produce androgen antagonists
    Cato, A. C. B.; Mink, S.; Becker, M.; Shatkina, L.
    2000. Meeting of the European Society of Human Reproduction and Embryology, Bologna, I, June 25-28, 2000
  114. Rapid signalling by androgen receptor in prostate cancer cells
    Peterziel, H.; Mink, S.; Schonert, A.; Becker, M.; Klocker, H.; Cato, A. C. B.
    1999. Oncogene, 18, 6322–29
  115. A nuclear action of the Eukaryotic cochaperone RAP46 in downregulation of glucocorticoid receptor activity
    Schneikert, J.; Hübner, S.; Martin, E.; Cato, A. C. B.
    1999. The Journal of Cell Biology, 146, 929–40
  116. Androgen receptor signalling pathways: role of BAG-IL in androgen receptor action
    Shatkina, L.; Mink, S.; Cato, A. C. B.
    1999. 28.Colloquium Endocrinologicum, Heidelberg, 5.November 1999
  117. Die Rolle der Kerntranslokation des Co-Chaperons RAP46 in der Regulation der transaktivierenden Wirkung des Glucocorticoidrezeptors
    Hübner, S.; Schneickert, J.; Martin, E.; Cato, A. C. B.
    1999. 28.Colloquium Endocrinologicum, Heidelberg, 5.November 1999
  118. Steroid hormone receptors and their coactivators and corepressors
    Cato, A. C. B.
    1999. 3rd Postgraduate Course in Molecular and Cellular Endocrinology, European Federation of Endocrine Societies, Münster, July 7-11, 1999
  119. Mechanism of androgen receptor activation and possible implications for chemoprevention trials
    Klocker, H.; Culig, Z.; Eder, I. E.; Nessler-Menardi, C.; Hobisch, A.; Putz, T.; Bartsch, G.; Peterziel, H.; Cato, A. C. B.
    1999. European Urology, 35, 413–19
  120. Androgen receptor action: two receptors-two ligands theory revisited
    Cato, A. C. B.
    1999. Round Table Discussion on PR and AR Isoforms, Schering AG, Berlin, July 5, 1999
  121. Eukaryotic cochaperone RAP46/BAG-1M as potential specificity determinant in corticosteroid receptor action
    Schneikert, J.; Hübner, S.; Crocoll, A.; Martin, E.; Cato, A. C. B.
    1999. Forefront Meeting of the Internat.Soc.of Nephrology ’News in Aldosterone Action’, Paris, F, August 15-18, 1999
  122. The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription
    Ortiz, L.; Aza-Blanc, P.; Zannini, M.; Cato, A. C. B.; Santisteban, P.
    1999. The Journal of Biological Chemistry, 274, 15213–21
  123. Expression, structure, and function of androgen receptor in advanced prostatic carcinoma
    Culig, Z.; Hobisch, A.; Hittmair, A.; Peterziel, H.; Cato, A. C. B.; Bartsch, G.; Klocker, H.
    1999. The Prostate, (1998), 35, 63–70
  124. Regulation of E-cadherin gene expression during tumor progression: the role of a new Ets-binding site and the E-pal element
    Rodrigo, I.; Cato, A. C. B.; Cano, A.
    1999. Experimental Cell Research, 248, 358–71
  125. Androgen receptor signaling in prostate cancer cells
    Cato, A. C. B.; Krug, H. F.; Peterziel, H.
    1999. 23.Jahrestagung der Deutschen Gesellschaft für Zellbiologie, Rostock, 14.-18.März 1999