Welcome to the Institute of Biological and Chemical Systems – Functional Molecular Systems (IBCS-FMS)

IBCS-Functional Molecular Systems is an interdisciplinary institute combining fundamental research in Biology and Chemistry.
Our aim is to improve our understanding of biological processes (e.g. cellular communication or disease progression) using advanced materials and chemical processes.
We focus on developing new smart materials, miniaturized high content screening methods as well as design of novel biomedical tools for the treatment of diseases.




Specific Focuses of IBCS-FMS:

Biology:        Cell adhesion molecules, Wnt signaling 
Chemistry:    Combinatorial chemistry, surface chemistry, polymer chemistry

Technology Transfer at IBCS-FMS:

Several aspects of our research at IBCS-FMS have been transferred into Start-Ups:




2 first prizes - NEULAND Innovation Contest 2021

- „LONGCOVIDMA: High-throughput testing of new efficient agents against LongCovid and Covid19 brain infections“ by Prof. Dr. Ute Schepers, Dr. Nicole Jung, Prof. Dr. Pavel Levkin, Prof. Dr. Stefan Bräse, Dr. Claudine Herlan, Dr. Anke Deckers and Dr. Anna Popova
- „Aquarray“ by Prof. Dr. Stefan Bräse and Prof. Dr. Pavel Levkin

Link to Homepage
Designing Inherently Photodegradable Cell-Adhesive Hydrogels for 3D Cell Culture

Check out recent publication of the Levkin Group in collaboration with Ute Schepers (IFG-CB) where they combined GelMA with PEG based gels to create photodegradable and biocompatible hydrogels for 3D cell culture.

Link to publication
Check out the new paper from the Orian-Rousseau group in "Blood"

CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues
Xiaobing Yu, Leonel Munoz-Sagredo, Karolin Streule, Patricia Muschong, Elisabeth Bayer, Romina Judith Walter, Julia Christine Gutjahr, Richard Greil, Miguel L Concha, Carsten Müller-Tidow, Tanja Nicole Hartmann, Véronique Orian-Rousseau

Link to paper
Latest Advanced Materials Paper

Introducing fully liquid "3D" structures that can contain organic liquids. Since there are no solid parts, it is self-healing, adaptive, and the liquid walls can release or extract components from the confined liquid.

Check out our paper “Liquid Wells as Self-Healing, Functional Analogues to Solid Vessels”:

Link to paper
From bench to bedside – Interview with Prof. Dr. Véronique Orian-Rousseau

You can read the whole interview here:

EURIdoc program

Orian-Rousseau Group:
EURIdoc: Eucor Upper Rhine Immunology doctoral programme (Marie Curie Action- COFUND)
The Orian-Rousseau group is part of the EURIdoc program focused on immunology. The project will tackle the immune components participating in the development of pancreatic tumors.

KIT press release
3D printing of inherently nanoporous structures
3D printing of inherently nanoporous structures

A new Nature Communication article from the Levkin Group: “3D printing of inherently nanoporous structures". Collaboration with Martin Wegener and Britta Nestler.
>> More in the News section

KIT press release
Invitation to join the editorial advisory board

Pavel Levkin accepts an invitation to join the editorial advisory board of Advanced Materials Interfaces (Wiley).

Newest Advanced Materials paper

Have a look at our newest Advanced Materials paper on "Assembly of Multi‐Spheroid Cellular Architectures by Programmable Droplet Merging".

319Anastasiya Sultanova , KIT
New research building at Campus North opened

Biology meets chemistry: Interdisciplinary research on 5 800 square meters. The new building was officially opened on October 29, 2020.

New HeiKa project (Orian-Rousseau Group in cooperation with Dr Lucas Schirmer) coordinated by Dr. Leonel Munoz

Title: “Decoding astroglial CD44 function in neuroinflammation”

New HeiKa project (Levkin Group in cooperation with Prof. Krijgsveld) coordinated by Dr. Anna Popova

Title: “Proteomics-on-c-Chip: Combining Droplet Microarrays and Mass Spectrometry for Single-Cell Proteomics”


With their decision to fund nine consortia, the Federal Government and the Federal States have set a further course for the establishment of NFDI in the Joint Science Conference (GWK).  Based on a funding recommendation by the German Research Foundation (DFG), the NFDI4Chem (National Research Data Infrastructure for Chemistry) consortium was also selected for funding.
The Compound Platform team contributes, among other things, the developments in the field of software development and is pleased to be able to contribute to the establishment of a sustainable infrastructure as part of NFDI4Chem.

Maximilian Benz

Congratulations to Maximilian Benz for winning the Carl-Roth-Förderpreis of the German Chemical Society (GDCh) for his work on the miniaturization of chemical synthesis and biological experiments.

New EUCOR Seed Money

New EUCOR Seed Money funding for the project “Exploiting the CXCR4-CD44 axis for cancer treatment”