Welcome to the Institute of Biological and Chemical Systems – Functional Molecular Systems (IBCS-FMS)
IBCS-Functional Molecular Systems is an interdisciplinary institute combining fundamental research in Biology and Chemistry.
Our aim is to improve our understanding of biological processes (e.g. cellular communication or disease progression) using advanced materials and chemical processes.
We focus on developing new smart materials, miniaturized high content screening methods as well as design of novel biomedical tools for the treatment of diseases.
Specific Focuses of IBCS-FMS:
Biology: Cell adhesion molecules, Wnt signaling
Chemistry: Combinatorial chemistry, surface chemistry, polymer chemistry
Technology Transfer at IBCS-FMS:
Several aspects of our research at IBCS-FMS have been transferred into Start-Ups:
Flyer [ PDF ]
As of July 1, Professor Siegfried Waldvogel (JGU Mainz) is the new senior scientist and group leader at the IBCS-FMS in a part-time capacity.
Congratulations to Lisa-Marie Mehner (Orian-Rousseau Group) for receiving the poster award for an outstanding poster presentation (1st Place) at the FEBS Advanced Lecture Course on Matrix Pathobiology in Crete, Greece.
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
Romina J. Walter, Steffen J. Sonnentag, Leonel Munoz-Sagredo, Melanie Merkel, Ludovic Richert, Felix Bunert, Yvonne M. Heneka, Thomas Loustau, Michael Hodder, Rachel A. Ridgway, Owen J. Sansom, Yves Mely, Ulrich Rothbauer, Mark Schmitt & Véronique Orian-Rousseau
Chemistry Fund supports Karlsruhe Institute of Technology - 5,000 euros for more digitalization in chemistry education.
New article by Stafan Bräse published at Journal of the American Chemical Society.
Levkin Group publishes a work on "Substrate-Independent and Re-Writable Surface Patterning by Combining Polydopamine Coatings, Silanization, and Thiol-Ene Reaction" in Advanced Functional Materials.
Congratulation to Shuai and all co-authors!
Check out Levkin Group´s recent Advanced Functional Materials paper on photodegradable organogels and their use to create organogel patterns and structures, as well as their use as positive photoresists. Collaboration with Patrick Theato.
Congratulation to Johannes Scheiger and all co-authors!
KIT Invests About Four Million Euros in Facility for Automated Synthesis - Efficient processes to accelerate the development of innovative materials
- „LONGCOVIDMA: High-throughput testing of new efficient agents against LongCovid and Covid19 brain infections“ by Prof. Dr. Ute Schepers, Dr. Nicole Jung, Prof. Dr. Pavel Levkin, Prof. Dr. Stefan Bräse, Dr. Claudine Herlan, Dr. Anke Deckers and Dr. Anna Popova
- „Aquarray“ by Prof. Dr. Stefan Bräse and Prof. Dr. Pavel Levkin
Check out recent publication of the Levkin Group in collaboration with Ute Schepers (IFG-CB) where they combined GelMA with PEG based gels to create photodegradable and biocompatible hydrogels for 3D cell culture.
CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues
Xiaobing Yu, Leonel Munoz-Sagredo, Karolin Streule, Patricia Muschong, Elisabeth Bayer, Romina Judith Walter, Julia Christine Gutjahr, Richard Greil, Miguel L Concha, Carsten Müller-Tidow, Tanja Nicole Hartmann, Véronique Orian-Rousseau
Introducing fully liquid "3D" structures that can contain organic liquids. Since there are no solid parts, it is self-healing, adaptive, and the liquid walls can release or extract components from the confined liquid.
Check out our paper “Liquid Wells as Self-Healing, Functional Analogues to Solid Vessels”:Link to paper
You can read the whole interview here:
EURIdoc: Eucor Upper Rhine Immunology doctoral programme (Marie Curie Action- COFUND)
The Orian-Rousseau group is part of the EURIdoc program focused on immunology. The project will tackle the immune components participating in the development of pancreatic tumors.