Publications 2022
-
Droplet Microarray as a Powerful Platform for Seeking New Antibiotics Against Multidrug‐Resistant Bacteria
Lei, W.; Deckers, A.; Luchena, C.; Popova, A.; Reischl, M.; Jung, N.; Bräse, S.; Schwartz, T.; Krimmelbein, I. K.; Tietze, L. F.; Levkin, P. A.
2022. Advanced Biology, 6 (12), Art.-Nr.: 2200166. doi:10.1002/adbi.202200166 -
Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
Trouvilliez, S.; Cicero, J.; Lévêque, R.; Aubert, L.; Corbet, C.; Van Outryve, A.; Streule, K.; Angrand, P.-O.; Völkel, P.; Magnez, R.; Brysbaert, G.; Mysiorek, C.; Gosselet, F.; Bourette, R.; Adriaenssens, E.; Thuru, X.; Lagadec, C.; de Ruyck, J.; Orian-Rousseau, V.; Le Bourhis, X.; Toillon, R.-A.
2022. Journal of Experimental & Clinical Cancer Research, 41 (1), Art.-Nr. 110. doi:10.1186/s13046-022-02314-4 -
Targeted deletion of Cd44 from pancreatic stellate cells impacts tumor growth. PhD dissertation
Heneka, Y. M.
2022, November 25. Karlsruher Institut für Technologie (KIT) -
A Computational Workflow for Interdisciplinary Deep Learning Projects utilizing bwHPC Infrastructure
Schilling, M.; Neumann, O.; Scherr, T.; Cui, H.; Popova, A. A.; Levkin, P. A.; Götz, M.; Reischl, M.
2022. Proceedings of the 7th bwHPC Symposium, 69–74, Kommunikations- und Informationszentrum (kiz). doi:10.18725/OPARU-46069 -
Tough, Self-Healing, and Conductive Elastomer ─Ionic PEGgel
Wang, Z.; Lai, Y.- cheng; Chiang, Y.- tang; Scheiger, J. M.; Li, S.; Dong, Z.; Cai, Q.; Liu, S.; Hsu, S.- hui; Chou, C.- ching; Levkin, P. A.
2022. ACS Applied Materials and Interfaces, 14 (44), 50152–50162. doi:10.1021/acsami.2c14394 -
UV Light Induced Surface Patterning and Recycling Strategies. PhD dissertation
Li, S.
2022, October 26. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000150401 -
Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First
Experiments
Frei, A.; Elliott, A. G.; Kan, A.; Dinh, H.; Bräse, S.; Bruce, A. E.; Bruce, M. R.; Chen, F.; Humaidy, D.; Jung, N.; King, A. P.; Lye, P. G.; Maliszewska, H. K.; Mansour, A. M.; Matiadis, D.; Muñoz, M. P.; Pai, T.-Y.; Pokhrel, S.; Sadler, P. J.; Sagnou, M.; Taylor, M.; Wilson, J. J.; Woods, D.; Zuegg, J.; Zuegg, J.; Meyer, W.; Cain, A. K.; Cooper, M. A.
2022. Journal of the American Chemical Society, 2 (10), 2277–2294. doi:10.1021/jacsau.2c00308 -
Copper Complexes of 1,4-Naphthoquinone Containing Thiosemicarbazide and Triphenylphosphine Oxide Moieties; Synthesis and Identification by NMR, IR, Mass, UV Spectra, and DFT Calculations
Alshammari, M. B.; Aly, A. A.; Bräse, S.; Nieger, M.; Ibrahim, M. A. A.; Abd El-Haleem, L. E.
2022. ACS Omega, 7 (38), 34463–34475. doi:10.1021/acsomega.2c04113 -
Droplet Microarray Based Screening Identifies Proteins for Maintaining Pluripotency of hiPSCs
Liu, Y.; Bertels, S.; Reischl, M.; Peravali, R.; Bastmeyer, M.; Popova, A. A.; Levkin, P. A.
2022. Advanced Healthcare Materials, 11 (18), Art.-Nr.: 2200718. doi:10.1002/adhm.202200718 -
Design Strategies for Structurally Controlled Polymer Surfaces via Cyclophane‐Based CVD Polymerization and Post‐CVD Fabrication
Hassan, Z.; Varadharajan, D.; Zippel, C.; Begum, S.; Lahann, J.; Bräse, S.
2022. Advanced Materials, 34 (37), Art.-Nr.: 2201761. doi:10.1002/adma.202201761 -
A Reactive Superhydrophobic Platform for Living Photolithography
Xie, X.; Chen, X.; Levkin, P. A.; Feng, W.
2022. Advanced Materials, 34 (36), Art.Nr. 2203619. doi:10.1002/adma.202203619 -
Organization and dynamics of MET and CD44v6 protein complexes at the plasma membrane. PhD dissertation
Tannoo, R. M.
2022, August 29. Karlsruher Institut für Technologie (KIT) -
Scope of tetrazolo[1,5-a] quinoxalines in CuAAC reactions for the synthesis of triazoloquinoxalines, imidazoloquinoxalines, and rhenium complexes thereof
Holzhauer, L.; Liagre, C.; Fuhr, O.; Jung, N.; Bräse, S.
2022. Beilstein Journal of Organic Chemistry, 18, 1088–1099. doi:10.3762/bjoc.18.111 -
Further Dimensions for Sensing in Biofluids: Distinguishing Bioorganic Analytes by the Salt-Induced Adaptation of a Cucurbit[7]uril-Based Chemosensor
Hu, C.; Jochmann, T.; Chakraborty, P.; Neumaier, M.; Levkin, P. A.; Kappes, M. M.; Biedermann, F.
2022. Journal of the American Chemical Society, 144 (29), 13084–13095. doi:10.1021/jacs.2c01520 -
Solid and Hollow Poly(p-xylylene) Particles Synthesis via Metal–Organic Framework-Templated Chemical Vapor Polymerization
Begum, S.; Behboodi-Sadabad, F.; Pramudya, Y.; Dolle, C.; Kozlowska, M.; Hassan, Z.; Mattern, C.; Gorji, S.; Heißler, S.; Welle, A.; Koenig, M.; Wenzel, W.; Eggeler, Y. M.; Bräse, S.; Lahann, J.; Tsotsalas, M.
2022. Chemistry of Materials, 34 (14), 6268–6278. doi:10.1021/acs.chemmater.2c00111 -
The role of CD44 in Listeria monocytogenes infection of the brain endothelium. PhD dissertation
Streule, K. L.
2022, July 21. Karlsruher Institut für Technologie (KIT) -
Dynamic Surface Modification of Metal–Organic Framework Nanoparticles via Alkoxyamine Functional Groups
Spiegel, S.; Wagner, I.; Begum, S.; Schwotzer, M.; Wessely, I.; Bräse, S.; Tsotsalas, M.
2022. Langmuir : the ACS journal of surfaces and colloids, 38 (21), 6531–6538. doi:10.1021/acs.langmuir.2c00085 -
A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway
Kuznik, N. C.; Solozobova, V.; Lee, I. I.; Jung, N.; Yang, L.; Nienhaus, K.; Ntim, E. A.; Rottenberg, J. T.; Muhle-Goll, C.; Kumar, A. R.; Peravali, R.; Gräßle, S.; Gourain, V.; Deville, C.; Cato, L.; Neeb, A.; Dilger, M.; Cramer von Clausbruch, C. A.; Weiss, C.; Kieffer, B.; Nienhaus, G. U.; Brown, M.; Bräse, S.; Cato, A. C. B.
2022. iScience, 25 (5), Art.Nr. 104175. doi:10.1016/j.isci.2022.104175 -
Poly(pentafluorobenzyl 2‐ylidene‐acetate): Polymerization and Postpolymerization Modification
Li, Z.; Zhang, H.; Theato, P.; Bräse, S.
2022. Macromolecular Chemistry and Physics, 223 (9), Art.-Nr.: 2100455. doi:10.1002/macp.202100455 -
Efficient Synthesis of Various Substituted (Thio)Ureas, Semicarbazides, Thiosemicarbazides, Thiazolidones, and Oxadiazole Derived from [2.2]Paracyclophane
Alshammari, M. B.; Aly, A. A.; Bräse, S.; Nieger, M.; Abd El-Haleem, L. E.
2022. ACS Omega, 7 (15), 12879–12890. doi:10.1021/acsomega.2c00141 -
Facile synthesis of new pyrano[3,2-c]quinolones via the reaction of quinolin-2-ones with ethene-1,2,3,4-tetracarbonitrile
Aly, A. A.; El-Naby, H. A. A.; Ahmed, E. K.; Shaker, R. M.; Gedamy, S. A.; Nieger, M.; Bräse, S.; El-Haleem, L. E. A.
2022. Monatshefte fur Chemie, 153, 277–284. doi:10.1007/s00706-022-02903-1 -
The jasmonate biosynthesis Gene OsOPR7 can mitigate salinity induced mitochondrial oxidative stress
Asfaw, K. G.; Liu, Q.; Eghbalian, R.; Purper, S.; Akaberi, S.; Dhakarey, R.; Münch, S. W.; Wehl, I.; Bräse, S.; Eiche, E.; Hause, B.; Bogeski, I.; Schepers, U.; Riemann, M.; Nick, P.
2022. Plant science, 316, Article no: 111156. doi:10.1016/j.plantsci.2021.111156 -
Waste to Resources – Elemental Sulfur for Functional Materials. PhD dissertation
Scheiger, J. M.
2022, February 15. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000141663 -
C–P bond formation of cyclophanyl-, and aryl halides a UV-induced photo Arbuzov reaction: a versatile portal to phosphonate-grafted scaffolds
Oßwald, S.; Zippel, C.; Hassan, Z.; Nieger, M.; Bräse, S.
2022. RSC Advances, 12 (6), 3309–3312. doi:10.1039/d2ra00094f -
Diversity-Oriented Synthesis of [2.2]Paracyclophane-derived Fused Imidazo[1,2-a]heterocycles by Groebke-Blackburn-Bienaymé Reaction: Accessing Cyclophanyl Imidazole Ligands Library
Stahlberger, M.; Schwarz, N.; Zippel, C.; Hohmann, J.; Nieger, M.; Hassan, Z.; Bräse, S.
2022. Chemistry - A European Journal, 28 (3), e202103511. doi:10.1002/chem.202103511 -
Design and synthesis of new thiazolidinone/uracil derivatives as antiproliferative agents targeting EGFR and/or BRAF
Alshammari, M. B.; Aly, A. A.; Youssif, B. G. M.; Bräse, S.; Ahmad, A.; Brown, A. B.; Ibrahim, M. A. A.; Mohamed, A. H.
2022. Frontiers in Chemistry, 10, Art.-Nr.: 1076383. doi:10.3389/fchem.2022.1076383 -
Design, Synthesis and Biological Evaluation of Syn and Anti-like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action
El-Sheref, E. M.; Ameen, M. A.; El-Shaieb, K. M.; Abdel-Latif, F. F.; Abdel-naser, A. I.; Brown, A. B.; Bräse, S.; Fathy, H. M.; Ahmad, I.; Patel, H.; Gomaa, H. A. M.; Youssif, B. G. M.; Mohamed, A. H.
2022. Molecules, 27 (24), Art.-Nr.: 8765. doi:10.3390/molecules27248765 -
Synthesis of novel amidines via one-pot three component reactions: Selective topoisomerase I inhibitors with antiproliferative properties
El-Sheref, E. M.; Tawfeek, H. N.; Hassan, A. A.; Bräse, S.; Elbastawesy, M. A. I.; Gomaa, H. A. M.; Mostafa, Y. A.; Youssif, B. G. M.
2022. Frontiers in Chemistry, 10, Art.-Nr.: 1039176. doi:10.3389/fchem.2022.1039176 -
Search for Alternative Two‐Step‐Absorption Photoinitiators for 3D Laser Nanoprinting
Bojanowski, N. M.; Vranic, A.; Hahn, V.; Rietz, P.; Messer, T.; Brückel, J.; Barner-Kowollik, C.; Blasco, E.; Bräse, S.; Wegener, M.
2022. Advanced Functional Materials, 33 (39), Art.-Nr.: 2212482. doi:10.1002/adfm.202212482 -
Metal complexes of new thiocarbohydrazones of Cu(I), Co(II), and Ni(II); identification by NMR, IR, mass, UV spectra, and DFT calculations
Aly, A. A.; Abdallah, E. M.; Ahmed, S. A.; Awad, M. K.; Rabee, M. M.; Mostafa, S. M.; Bräse, S.
2022. Journal of Sulfur Chemistry, 44 (3), 282–303. doi:10.1080/17415993.2022.2145846 -
Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behaviour in colon cancer
Xu, T.; Verhagen, M.; Joosten, R.; Sun, W.; Sacchetti, A.; Munoz Sagredo, L.; Orian-Rousseau, V.; Fodde, R.
2022. eLife, 11, Art.-Nr.: e82006. doi:10.7554/eLife.82006 -
Different Involvement of Vimentin during Invasion by Listeria monocytogenes at the Blood–Brain and the Blood–Cerebrospinal Fluid Barriers In Vitro
Banovic, F.; Schulze, S.; Abu Mraheil, M.; Hain, T.; Chakraborty, T.; Orian-Rousseau, V.; Moroniak, S.; Weiss, C.; Ishikawa, H.; Schroten, H.; Adam, R.; Schwerk, C.
2022. International Journal of Molecular Sciences, 23 (21), Art.Nr. 12908. doi:10.3390/ijms232112908 -
Synthesis and Identification of New N,N-Disubstituted Thiourea, and Thiazolidinone Scaffolds Based on Quinolone Moiety as Urease Inhibitor
Elshaier, Y. A. M. M.; Aly, A. A.; Abdel-Aziz, M.; Fathy, H. M.; Brown, A. B.; Bräse, S.; Ramadan, M.
2022. Molecules, 27 (20), Art.-Nr.: 7126. doi:10.3390/molecules27207126 -
Design, synthesis, crystal structures and biological evaluation of some 1,3-thiazolidin-4-ones as dual CDK2/EGFR potent inhibitors with potential apoptotic antiproliferative effects
Tawfeek, H. N.; Hassan, A. A.; Bräse, S.; Nieger, M.; Mostafa, Y. A.; Gomaa, H. A. M.; Youssif, B. G. M.; El-Shreef, E. M.
2022. Arabian Journal of Chemistry, 15 (11), Art.-Nr.: 104280. doi:10.1016/j.arabjc.2022.104280 -
Material‐Independent 3D Patterning Via Two‐Photon Lithography and Discontinuous Wetting
Dong, Z.; Monti, J.; Cui, H.; Welle, A.; Singaraju, S. A.; Blasco, E.; Levkin, P. A.
2022. Advanced Materials Technologies, 8 (5), Artk. Nr.: 2201268. doi:10.1002/admt.202201268 -
CD44 expressed by myeloid cells promotes glioma invasion
Ivanova, E. L.; Costa, B.; Eisemann, T.; Lohr, S.; Boskovic, P.; Eichwald, V.; Meckler, J.; Jugold, M.; Orian-Rousseau, V.; Peterziel, H.; Angel, P.
2022. Frontiers in Oncology, 12, Art.Nr. 969787. doi:10.3389/fonc.2022.969787 -
Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections
Fresnais, M.; Liang, S.; Breitkopf, M.; Lindner, J. R.; Claude, E.; Pringle, S.; Levkin, P. A.; Demir, K.; Benzel, J.; Sundheimer, J.; Statz, B.; Pajtler, K. W.; Pfister, S. M.; Haefeli, W. E.; Burhenne, J.; Longuespée, R.
2022. Pharmaceuticals, 15 (6), Art.Nr. 694. doi:10.3390/ph15060694 -
Functionalized C
-Symmetric Building Blocks—The Chemistry of Triaminotrimesic Acid
Schmidt, L.; Wagner, D.; Nieger, M.; Bräse, S.
2022. Molecules, 27 (14), Art.-Nr.: 4369. doi:10.3390/molecules27144369 -
Azides in the Synthesis of Various Heterocycles
Nayl, A. A.; Aly, A. A.; Arafa, W. A. A.; Ahmed, I. M.; Abd-Elhamid, A. I.; El-Fakharany, E. M.; Abdelgawad, M. A.; Tawfeek, H. N.; Bräse, S.
2022. Molecules, 27 (12), Art.Nr. 3716. doi:10.3390/molecules27123716 -
Facile synthesis of hydrazono bis-4-oxothiazolidines
Mostafa, S. M.; Aly, A. A.; Bräse, S.; Nieger, M.; Mohamed, A. H.
2022. Journal of Sulfur Chemistry, 43 (6), 606–619. doi:10.1080/17415993.2022.2083454 -
Review of the Recent Advances in Electrospun Nanofibers Applications in Water Purification
Nayl, A. A.; Abd-Elhamid, A. I.; Awwad, N. S.; Abdelgawad, M. A.; Wu, J.; Mo, X.; Gomha, S. M.; Aly, A. A.; Bräse, S.
2022. Polymers, 14 (8), Art.-Nr.: 1594. doi:10.3390/polym14081594 -
Recent Progress and Potential Biomedical Applications of Electrospun Nanofibers in Regeneration of Tissues and Organs
Nayl, A. A.; Abd-Elhamid, A. I.; Awwad, N. S.; Abdelgawad, M. A.; Wu, J.; Mo, X.; Gomha, S. M.; Aly, A. A.; Bräse, S.
2022. Polymers, 14 (8), Art.-Nr.: 1508. doi:10.3390/polym14081508 -
X-ray Structure Analyses of 4-Hydroxy-1-Methylquinolin-2(1H)-One, 6-Ethyl-4-Hydroxy-2 H-Pyrano[3,2-c]Quinoline-2,5(6H)-Dione, (E)-4-(2-Benzylidene-Hydrazineyl)Quinolin-2(1H)-One and Diethyl (E)-2-(2-(1-Methyl-2-Oxo-1,2-Dihydro-Quinolin-4-yl)Hydrazineylidene)Succinate
Aly, A. A.; Nieger, M.; Bräse, S.; Bakheet, M. E. M.
2022. Journal of Chemical Crystallography, 53, 38–49. doi:10.1007/s10870-022-00939-z -
Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′ ]diquinoline-6,7(5H,8H)-diones
Mostafa, S. M.; Aly, A. A.; Hassan, A. A.; Osman, E. M.; Bräse, S.; Nieger, M.; Ibrahim, M. A. A.; Mohamed, A. H.
2022. Molecules, 27 (7), Art.-Nr.: 2125. doi:10.3390/molecules27072125 -
Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors
Mostafa, S. M.; Aly, A. A.; Bräse, S.; Nieger, M.; Abdelhafez, S. M. N.; Abdelzaher, W. Y.; Abdelhafez, E.-S. M. N.
2022. Molecules, 27 (7), Art.Nr.: 2266. doi:10.3390/molecules27072266 -
Fluorescent annulated imidazo[4,5- c ]isoquinolines via a GBB-3CR/imidoylation sequence – DNA-interactions in pUC-19 gel electrophoresis mobility shift assay
Stahlberger, M.; Steinlein, O.; Adam, C. R.; Rotter, M.; Hohmann, J.; Nieger, M.; Köberle, B.; Bräse, S.
2022. Organic & Biomolecular Chemistry, 20 (17), 3598–3604. doi:10.1039/d2ob00372d -
Wavelength Orthogonal Photodynamic Networks
Truong, V. X.; Ehrmann, K.; Seifermann, M.; Levkin, P. A.; Barner-Kowollik, C.
2022. Chemistry - A European Journal, 28 (25), Art.Nr. e202104466. doi:10.1002/chem.202104466 -
“Cells‐to‐cDNA on Chip”: Phenotypic assessment and gene expression analysis from live cells in nanoliter volumes using droplet microarrays
Chakraborty, S.; Luchena, C.; Elton, J. J.; Schilling, M. P.; Reischl, M.; Roux, M.; Levkin, P. A.; Popova, A. A.
2022. Advanced Healthcare Materials, 11 (12), Art.-Nr.: 2102493. doi:10.1002/adhm.202102493 -
Inverse Vulcanization of Norbornenylsilanes: Soluble Polymers with Controllable Molecular Properties via Siloxane Bonds
Scheiger, J. M.; Hoffmann, M.; Falkenstein, P.; Wang, Z.; Rutschmann, M.; Scheiger, V. W.; Grimm, A.; Urbschat, K.; Sengpiel, T.; Matysik, J.; Wilhelm, M.; Levkin, P. A.; Theato, P.
2022. Angewandte Chemie - International Edition, 61 (16), Art.-Nr.: e202114896. doi:10.1002/anie.202114896 -
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
Walter, R. J.; Sonnentag, S. J.; Munoz-Sagredo, L.; Merkel, M.; Richert, L.; Bunert, F.; Heneka, Y. M.; Loustau, T.; Hodder, M.; Ridgway, R. A.; Sansom, O. J.; Mely, Y.; Rothbauer, U.; Schmitt, M.; Orian-Rousseau, V.
2022. Cell death & disease, 13 (2), Art.-Nr.: 168. doi:10.1038/s41419-022-04607-0 -
Simple assessment of viability in 2D and 3D cell microarrays using single step digital imaging
Popova, A. A.; Reischl, M.; Kazenmaier, D.; Cui, H.; Amberger, T.; Levkin, P. A.
2022. SLAS technology, 27 (1), 44–53. doi:10.1016/j.slast.2021.10.017 -
Surfaces Decorated with Enantiomorphically Pure Polymer Nanohelices via Hierarchical Chirality Transfer across Multiple Length Scales
Varadharajan, D.; Nayani, K.; Zippel, C.; Spuling, E.; Cheng, K. C.; Sarangarajan, S.; Roh, S.; Kim, J.; Trouillet, V.; Bräse, S.; Abbott, N. L.; Lahann, J.
2022. Advanced Materials, 34 (9), Art.-Nr.: 2108386. doi:10.1002/adma.202108386 -
Fluorinated dibenzo[a,c]-phenazine-based green to red thermally activated delayed fluorescent OLED emitters
Hong, G.; Si, C.; Gupta, A. K.; Bizzarri, C.; Nieger, M.; Samuel, I. D. W.; Zysman-Colman, E.; Bräse, S.
2022. Journal of materials chemistry / C, 10 (12), 4757–4766. doi:10.1039/d1tc04918f -
Functional Selectivity of Coumarin Derivates Acting via GPR55 in Neuroinflammation
Apweiler, M.; Streyczek, J.; Saliba, S. W.; Collado, J. A.; Hurrle, T.; Gräßle, S.; Muñoz, E.; Normann, C.; Hellwig, S.; Bräse, S.; Fiebich, B. L.
2022. International Journal of Molecular Sciences, 23 (2), 959. doi:10.3390/ijms23020959 -
Equilibrium droplet shapes on chemically patterned surfaces: theoretical calculation, phase-field simulation, and experiments
Wu, Y.; Kuzina, M.; Wang, F.; Reischl, M.; Selzer, M.; Nestler, B.; Levkin, P. A.
2022. Journal of Colloid and Interface Science, 606, 1077–1086. doi:10.1016/j.jcis.2021.08.029