Publications 2024


  1. Novel trends in homogenous and superwettable functional surfaces with a focus on siloxane and silane chemistry. PhD dissertation
    Paulssen, D.
    2024, August 22. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000171093/v2 Full textFull text of the publication as PDF document 
  2. Nanoliter Droplet Microarrays Combined with Impedance Spectroscopy and Sandwiching Method for Advancements in Miniaturized Cell Culture and Screening. PhD dissertation
    Zhou, M.
    2024, August 19. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000172875 Full textFull text of the publication as PDF document 
  3. Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors
    Al-Wahaibi, L. H.; Elshamsy, A. M.; Ali, T. F. S.; Youssif, B. G. M.; Bräse, S.; Abdel-Aziz, M.; El-Koussi, N. A.
    2024. ACS Omega, 9 (32), 34358–34369. doi:10.1021/acsomega.4c01361 Full textFull text of the publication as PDF document 
  4. New Diaryl-1,2,4-triazolo[3,4- a ]pyrimidine Hybrids as Selective COX-2/sEH Dual Inhibitors with Potent Analgesic/Anti-inflammatory and Cardioprotective Properties
    Al-Wahaibi, L. H.; Abdel-Rahman, M. H.; El-Adl, K.; Youssif, B. G. M.; Bräse, S.; Abdel-Aziz, S. A.
    2024. ACS Omega, 9 (31), 33494–33509. doi:10.1021/acsomega.4c00870 Full textFull text of the publication as PDF document 
  5. Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation
    Vidyakina, A. A.; Silonov, S. A.; Govdi, A. I.; Ivanov, A. Y.; Podolskaya, E. P.; Balova, I. A.; Bräse, S.; Danilkina, N. A.
    2024. Organic & Biomolecular Chemistry. doi:10.1039/d4ob01032a Full textFull text of the publication as PDF document 
  6. Convenient synthesis and X-ray determination of 2-amino-6 H -1,3,4-thiadiazin-3-ium bromides endowed with antiproliferative activity
    Tawfeek, H. N.; Abdelmoez, A.; Dahlous, K. A.; Youssif, B. G. M.; Bräse, S.; Rissanen, K.; Nieger, M.; El-Sheref, E. M.
    2024. RSC Advances, 14 (25), 17866 – 17876. doi:10.1039/D4RA02531H Full textFull text of the publication as PDF document 
  7. 3D printing of reactive macroporous polymers via thiol–ene chemistry and polymerization-induced phase separation
    Mandsberg, N. K.; Aslan, F.; Dong, Z.; Levkin, P. A.
    2024. Chemical Communications, 60 (45), 5872 – 5875. doi:10.1039/D4CC00466C Full textFull text of the publication as PDF document 
  8. Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
    Neeb, A.; Figueiredo, I.; Bogdan, D.; Cato, L.; Stober, J.; Jiménez-Vacas, J. M.; Gourain, V.; Lee, I. I.; Seeger, R.; Muhle-Goll, C.; Gurel, B.; Welti, J.; Nava Rodrigues, D.; Rekowski, J.; Qiu, X.; Jiang, Y.; Di Micco, P.; Mateos, B.; Bielskutė, S.; Riisnaes, R.; Ferreira, A.; Miranda, S.; Crespo, M.; Buroni, L.; Ning, J.; Carreira, S.; Bräse, S.; Jung, N.; Gräßle, S.; Swain, A.; Salvatella, X.; Plymate, S. R.; Al-Lazikani, B.; Long, H. W.; Yuan, W.; Brown, M.; Cato, A. C. B.; de Bono, J. S.; Sharp, A.
    2024. Molecular Cancer Therapeutics, 23 (6), 791–808. doi:10.1158/1535-7163.MCT-23-0354 Full textFull text of the publication as PDF document 
  9. Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and topoisomerase IV inhibitors endowed with antibacterial properties
    Al-Wahaibi, L. H.; Mahmoud, M. A.; Alzahrani, H. A.; Abou-Zied, H. A.; Gomaa, H. A. M.; Youssif, B. G. M.; Bräse, S.; Rabea, S. M.
    2024. Frontiers in Chemistry, 12, Art.-Nr.: 1419242. doi:10.3389/fchem.2024.1419242 Full textFull text of the publication as PDF document 
  10. A New Class of Chiral Polyethers and Polyesters Based on the [2.2]Paracyclophane Scaffold
    Kern, P.; Tappert, H.; Bräse, S.
    2024. Polymers, 16 (11), Art.-Nr.: 1603. doi:10.3390/polym16111603 Full textFull text of the publication as PDF document 
  11. Substituted Pyrrole‐based Schiff Bases: Effect On The Luminescence Of Neutral Heteroleptic Cu(I) Complexes
    Ferraro, V.; Fuhr, O.; Bizzarri, C.; Bräse, S.
    2024. European Journal of Inorganic Chemistry, 27 (17), Art.-Nr.: e202400080. doi:10.1002/ejic.202400080 Full textFull text of the publication as PDF document 
  12. Application of High-Throughput Screenings on the Interfaces of Chemistry, Biology and Material Science. PhD dissertation
    Seifermann, M.
    2024, May 14. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000168798 
  13. Parallel and Miniaturized Combinatorial Synthesis and Analysis of Small Molecules on Droplet Microarray. PhD dissertation
    Höpfner, J.
    2024, May 14. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000168797 
  14. Miniaturized Chemistry: from Synthesis in Nanoliters to Purification and High-Throughput Screening. PhD dissertation
    Wiedmann, J. J.
    2024, March 26. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000166093 
  15. Reversing the stereoselectivity of intramolecular [2+2] photocycloaddition utilizing cucurbit[8]uril as a molecular flask
    Qiu, X.; Seibert, J.; Fuhr, O.; Biedermann, F.; Bräse, S.
    2024. Chemical Communications, 60 (24), 3267–3270. doi:10.1039/D3CC05783F Full textFull text of the publication as PDF document 
  16. Stereoselective synthesis and X-ray structure determination of novel 1,2-dihydroquinolinehydrazonopropanoate derivatives
    Tawfeek, H. N.; Tawfeek, A. M.; Bräse, S.; Nieger, M.; El-Sheref, E. M.
    2024. Heliyon, 10 (4), Art.-Nr.: e25248. doi:10.1016/j.heliyon.2024.e25248 Full textFull text of the publication as PDF document 
  17. Optimized Detection of Volatile Organic Compounds Utilizing Durable and Selective Arrays of Tailored UiO-66-X SURMOF Sensors
    Okur, S.; Hashem, T.; Bogdanova, E.; Hodapp, P.; Heinke, L.; Bräse, S.; Wöll, C.
    2024. ACS Sensors, 9 (2), 622–630. doi:10.1021/acssensors.3c01575 
  18. ANDeS: An automated nanoliter droplet selection and collection device
    Urrutia Gómez, J. E.; Faraj, R. E. K. E.; Braun, M.; Levkin, P. A.; Popova, A. A.
    2024. SLAS Technology, 29 (1), Art.-Nr.: 100118. doi:10.1016/j.slast.2023.11.002 Full textFull text of the publication as PDF document 
  19. From Mono- to Polynuclear 2-(Diphenylphosphino)pyridine-Based Cu(I) and Ag(I) Complexes: Synthesis, Structural Characterization, and DFT Calculations
    Busch, J. M.; Rehak, F. R.; Ferraro, V.; Nieger, M.; Kemell, M.; Fuhr, O.; Klopper, W.; Bräse, S.
    2024. ACS Omega, 9 (2), 2220–2233. doi:10.1021/acsomega.3c05755 Full textFull text of the publication as PDF document 
  20. Synthesis of substituted triazole–pyrazole hybrids using triazenylpyrazole precursors
    Gräßle, S.; Holzhauer, L.; Wippert, N.; Fuhr, O.; Nieger, M.; Jung, N.; Bräse, S.
    2024. Beilstein Journal of Organic Chemistry, 20, 1396 – 1404. doi:10.3762/bjoc.20.121 Full textFull text of the publication as PDF document 
  21. CART: Carrier‐Based Actuatable and Reprogrammable Transport
    Mandsberg, N. K.; Serna, J. A.; Levkin, P. A.
    2024. Advanced Functional Materials, 2406635. doi:10.1002/adfm.202406635 Full textFull text of the publication as PDF document 
  22. High-throughput screening for cell binding and repulsion peptides on multifunctionalized surfaces
    Sonnentag, S. J.; Jenne, F.; Orian-Rousseau, V.; Nesterov-Mueller, A.
    2024. Communications Biology, 7 (1), Art.-Nr.: 870. doi:10.1038/s42003-024-06541-7 Full textFull text of the publication as PDF document 
  23. (Semi-) Automatic Review Process for Common Compound Characterization Data in Organic Synthesis
    Huang, Y.-C.; Tremouilhac, P.; Kuhn, S.; Huang, P.-C.; Lin, C.-L.; Schlörer, N.; Taubert, O.; Götz, M.; Jung, N.; Bräse, S.
    2024. ChemRxiv. doi:10.26434/chemrxiv-2024-1r9tb Full textFull text of the publication as PDF document 
  24. Thermally Activated Delayed Fluorescence (TADF) Materials Based on Earth‐Abundant Transition Metal Complexes: Synthesis, Design and Applications
    Ferraro, V.; Bizzarri, C.; Bräse, S.
    2024. Advanced Science, 2404866. doi:10.1002/advs.202404866 Full textFull text of the publication as PDF document 
  25. Effect of tert-butyl substitution on controlling the orientation of TADF emitters in guest–host systems
    Sahay, P.; Crovini, E.; Stavrou, K.; Zhang, Z.; Nguyên, B. M.; Wagner, D.; Strohriegl, P.; Bräse, S.; Monkman, A.; Zysman-Colman, E.; Brütting, W.
    2024. Journal of Materials Chemistry C. doi:10.1039/D4TC01195C 
  26. Enhancing Temperature Responsiveness of PNIPAM Through 3D‐Printed Hierarchical Porosity
    Liu, W.; Wang, Z.; Serna, J. A.; Debastiani, R.; Gomez, J. E. U.; Lu, L.; Yang, W.; Dong, Z.; Levkin, P. A.
    2024. Advanced Functional Materials, Artkl.Nr.: 2403794. doi:10.1002/adfm.202403794 Full textFull text of the publication as PDF document 
  27. From Molecules to Materials: Collaborative Research at the Chemistry—Materials Science Interface and Lessons Learned in Cyclophane Chemistry
    Hassan, Z.; Zysman-Colman, E.; Lahann, J.; Bräse, S.
    2024. Advanced Functional Materials, Art.-Nr.: 202403365. doi:10.1002/adfm.202403365 Full textFull text of the publication as PDF document 
  28. Doping Strategies for Tetrasubstituted Paracyclophane Hole Transport Layers in Perovskite Solar Cells
    Schulz, A. D.; Otterbach, S. A.; Tappert, H.; Elsing, D.; Wenzel, W.; Kozlowska, M.; Bräse, S.; Colsmann, A.; Röhm, H.
    2024. Advanced Functional Materials, Art.-Nr.: 2402110. doi:10.1002/adfm.202402110 Full textFull text of the publication as PDF document 
  29. Modulation of neuroinflammation and oxidative stress by targeting GPR55 – new approaches in the treatment of psychiatric disorders
    Apweiler, M.; Saliba, S. W.; Sun, L.; Streyczek, J.; Normann, C.; Hellwig, S.; Bräse, S.; Fiebich, B. L.
    2024. Molecular Psychiatry. doi:10.1038/s41380-024-02614-5 Full textFull text of the publication as PDF document 
  30. Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition
    Al-Wahaibi, L. H.; Elshamsy, A. M.; Ali, T. F. S.; Youssif, B. G. M.; Bräse, S.; Abdel-Aziz, M.; El-Koussi, N. A.
    2024. Frontiers in Chemistry, 12, Art.-Nr.: 1387923. doi:10.3389/fchem.2024.1387923 Full textFull text of the publication as PDF document 
  31. Extraction of the intrinsic rate constant for a photocyclization reaction in capillary microreactors using a simplified reactor model
    Li, J.; Šimek Tosino, H.; Ladewig, B. P.; Jung, N.; Bräse, S.; Dittmeyer, R.
    2024. Reaction Chemistry & Engineering. doi:10.1039/d4re00087k Full textFull text of the publication as PDF document 
  32. Targeting CD44 and other pleiotropic co-receptors as a means for broad inhibition of tumor growth and metastasis
    Mehner, L.-M.; Munoz-Sagredo, L.; Sonnentag, S. J.; Treffert, S. M.; Orian-Rousseau, V.
    2024. Clinical and Experimental Metastasis. doi:10.1007/s10585-024-10292-4 Full textFull text of the publication as PDF document 
  33. Linker aggregation engineering of TADF materials to tune carrier balance for highly efficient organic LEDs with long operational lifetime
    Zhang, Z.; Xia, R.; Wang, K.; Wu, Y.; Zang, P.; Gan, X.; Liao, Z.; Wei, B.; Wu, P.; Bräse, S.; Wang, Z.
    2024. Aggregate, Art.-Nr.: e588. doi:10.1002/agt2.588 Full textFull text of the publication as PDF document 
  34. Solvent‐Independent 3D Printing of Organogels
    Kuzina, M. A.; Hoffmann, M.; Mandsberg, N. K.; Domínguez, C. M.; Niemeyer, C. M.; Wilhelm, M.; Levkin, P. A.
    2024. Advanced Functional Materials, Art.-Nr.: 2403694. doi:10.1002/adfm.202403694 Full textFull text of the publication as PDF document 
  35. Anti-Neuroinflammatory Effects of a Macrocyclic Peptide-Peptoid Hybrid in Lipopolysaccharide-Stimulated BV2 Microglial Cells
    Sun, L.; Wilke Saliba, S.; Apweiler, M.; Akmermer, K.; Herlan, C.; Grathwol, C.; de Oliveira, A. C. P.; Normann, C.; Jung, N.; Bräse, S.; Fiebich, B. L.
    2024. International Journal of Molecular Sciences, 25 (8), Artkl.Nr.:4462. doi:10.3390/ijms25084462 Full textFull text of the publication as PDF document 
  36. A Novel Carbazolophane: A Comparison of the Performance of Two Planar Chiral CP‐TADF Emitters
    Seibert, J.; Xu, Y.; Hafeez, H.; Podlech, J.; Favereau, L.; Spuling, E.; Waldhelm, C.; Nieger, M.; Fuhr, O.; Hassan, Z.; Crassous, J.; Samuel, I. D. W.; Zysman-Colman, E.; Bräse, S.
    2024. Advanced Functional Materials, Art.-Nr.: 2401956. doi:10.1002/adfm.202401956 Full textFull text of the publication as PDF document 
  37. Synthetic methodology of pyrimido[4,5‐ b ]quinoline derivatives
    Tawfeek, H. N.; Hasanin, T. H. A.; Bräse, S.
    2024. Journal of Heterocyclic Chemistry, 61 (6), 971–1008. doi:10.1002/jhet.4815 
  38. Modulating and Accelerating Photolysis of Photoactivatable [2.2]Paracyclophane Aryl Azide in Supramolecular Host for Bioimaging
    Qiu, X.; Pohl, E.; Cai, Q.; Seibert, J.; Li, Y.; Leopold, S.; Fuhr, O.; Meier, M. A. R.; Schepers, U.; Bräse, S.
    2024. Advanced Functional Materials, Art.-Nr.: 2401938. doi:10.1002/adfm.202401938 Full textFull text of the publication as PDF document 
  39. Synthesis of Mono‐, Di‐, Tri‐, and Tetra‐cationic Pyridinium and Vinylpyridinium Modified [2.2]Paracyclophanes: Modular Receptors for Supramolecular Systems
    Wang, Y.; Li, Y.; Fuhr, O.; Nieger, M.; Hassan, Z.; Bräse, S.
    2024. ChemistryOpen, 13 (8), e202400024. doi:10.1002/open.202400024 Full textFull text of the publication as PDF document 
  40. Wetting Behavior of Inkjet-Printed Electronic Inks on Patterned Substrates
    Arya, P.; Wu, Y.; Wang, F.; Wang, Z.; Cadilha Marques, G.; Levkin, P. A.; Nestler, B.; Aghassi-Hagmann, J.
    2024. Langmuir, 40 (10), 5162–5173. doi:10.1021/acs.langmuir.3c03297 Full textFull text of the publication as PDF document 
  41. Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors
    Mahmoud, M. A.; Mohammed, A. F.; Salem, O. I. A.; Almutairi, T. M.; Bräse, S.; Youssif, B. G. M.
    2024. Journal of Enzyme Inhibition and Medicinal Chemistry, 39 (1), Art.-Nr.: 2305856. doi:10.1080/14756366.2024.2305856 Full textFull text of the publication as PDF document 
  42. Constructing [2.2]Paracyclophane‐Based Ultrasensitive Optical Fluorescent‐Phosphorescent Thermometer with Cucurbit[8]uril Supramolecular Assembly
    Qiu, X.; Zheng, T.; Runowski, M.; Woźny, P.; Martín, I. R.; Soler-Carracedo, K.; Piñero, C. E.; Lebedkin, S.; Fuhr, O.; Bräse, S.
    2024. Advanced Functional Materials, Art.-Nr.: 2313517. doi:10.1002/adfm.202313517 Full textFull text of the publication as PDF document 
  43. Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies
    Youssif, B. G. M.; Morcoss, M. M.; Bräse, S.; Abdel-Aziz, M.; Abdel-Rahman, H. M.; Abou El-Ella, D. A.; Abdelhafez, E. S. M. N.
    2024. Molecules, 29 (2), Art.-Nr.: 446. doi:10.3390/molecules29020446 Full textFull text of the publication as PDF document 
  44. High‐Throughput Miniaturized Synthesis of PROTAC‐Like Molecules
    Tian, Y.; Seifermann, M.; Bauer, L.; Luchena, C.; Wiedmann, J. J.; Schmidt, S.; Geisel, A.; Afonin, S.; Höpfner, J.; Brehm, M.; Liu, X.; Hopf, C.; Popova, A. A.; Levkin, P. A.
    2024. Small, Art.-Nr.: 2307215. doi:10.1002/smll.202307215 
  45. Azide Thermolysis Frameworks: Self‐inflating, Porous, and Lightweight Materials
    Brückel, J.; Matt, Y.; Schmidt, L.; Mattern, C. M.; Schepers, U.; Leopold, S.; Calkovsky, M.; Gerthsen, D.; Bräse, S.
    2024. ChemNanoMat, 10 (2), Art.-Nr.: e202300222. doi:10.1002/cnma.202300222 Full textFull text of the publication as PDF document 
  46. Modulating Aryl Azide Photolysis: Synthesis of a Room‐Temperature Phosphorescent Carboline in Cucurbit[7]uril Host
    Qiu, X.; Wang, Y.; Leopold, S.; Lebedkin, S.; Schepers, U.; Kappes, M. M.; Biedermann, F.; Bräse, S.
    2024. Small, 20 (16), Art.Nr.: 2307318. doi:10.1002/smll.202307318 Full textFull text of the publication as PDF document 
  47. Quantitative live imaging reveals a direct interaction between CD44v6 and MET in membrane domains upon activation with both MET ligands, HGF and internalin B
    Tannoo, R. M.; Richert, L.; Koschut, D.; Tomishige, N.; Treffert, S. M.; Kobayashi, T.; Mély, Y.; Orian-Rousseau, V.
    2024. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1866 (1), Art.-Nr. 184236. doi:10.1016/j.bbamem.2023.184236 Full textFull text of the publication as PDF document 
  48. High‐Performance Pressure Sensors Based on Shaped Gel Droplet Arrays
    Wang, Z.; Cai, Q.; Lu, L.; Levkin, P. A.
    2024. Small, 20 (5), Art.Nr.: 2305214. doi:10.1002/smll.202305214 Full textFull text of the publication as PDF document 
  49. Palladium‐Catalyzed Combinatorial Synthesis of Biphenyls on Droplet Microarrays at Nanoliter Scale
    Höpfner, J.; Brehm, M.; Levkin, P. A.
    2024. Small, 20 (4), Art.Nr.: 2304325. doi:10.1002/smll.202304325 Full textFull text of the publication as PDF document 
  50. The Impact of Digitalized Data Management on Materials Systems Workflows
    Tristram, F.; Jung, N.; Hodapp, P.; Schröder, R. R.; Wöll, C.; Bräse, S.
    2024. Advanced Functional Materials, 34 (20), Art.-Nr.: 2303615. doi:10.1002/adfm.202303615 Full textFull text of the publication as PDF document 
  51. Disulfide‐Bridged Dynamic Covalent Triazine Polymer Thin Films by Interface Polymerization: High Refractive Index with Excellent Optical Transparency
    Begum, S.; Kutonova, K.; Mauri, A.; Koenig, M.; Chan, K. C.; Sprau, C.; Dolle, C.; Trouillet, V.; Hassan, Z.; Leonhard, T.; Heißler, S.; Eggeler, Y. M.; Wenzel, W.; Kozlowska, M.; Bräse, S.
    2024. Advanced Functional Materials, 34 (20), Art.-Nr.: 2303929. doi:10.1002/adfm.202303929 Full textFull text of the publication as PDF document 
  52. Functional Material Systems Enabled by Automated Data Extraction and Machine Learning
    Kalhor, P.; Jung, N.; Bräse, S.; Wöll, C.; Tsotsalas, M.; Friederich, P.
    2024. Advanced Functional Materials, 34 (20), Art.Nr.: 2302630. doi:10.1002/adfm.202302630 Full textFull text of the publication as PDF document 
  53. Recent Advances of Transition Metal Complexes for Photopolymerization and 3D Printing under Visible Light
    Ferraro, V.; Adam, C. R.; Vranic, A.; Bräse, S.
    2024. Advanced Functional Materials, 34 (20), Art.-Nr.: 2302157. doi:10.1002/adfm.202302157 Full textFull text of the publication as PDF document 
  54. Selective Peptide Binders to the Perfluorinated Sulfonic Acid Ionomer Nafion
    Schmidt, D.; Gartner, P.; Berezkin, I.; Rudat, J.; Bilger, M.; Grünert, T.; Zimmerer, N.; Quarz, P.; Scharfer, P.; Brückel, J.; Jung, A. P.; Singh, P.; Pooja, P.; Meier, B.; Stahlberger, M.; Schabel, W.; Bräse, S.; Lanza, G.; Nesterov-Mueller, A.
    2024. Advanced Functional Materials, 34 (20), Article no: 2214932. doi:10.1002/adfm.202214932 Full textFull text of the publication as PDF document 
  55. Exploring Functional Photonic Devices made from a Chiral Metal–Organic Framework Material by a Multiscale Computational Method
    Zerulla, B.; Li, C.; Beutel, D.; Oßwald, S.; Holzer, C.; Bürck, J.; Bräse, S.; Wöll, C.; Fernandez-Corbaton, I.; Heinke, L.; Rockstuhl, C.; Krstić, M.
    2024. Advanced Functional Materials, 34 (20), Art.-Nr.: 2301093. doi:10.1002/adfm.202301093 Full textFull text of the publication as PDF document 
  56. Tough PEGgels by In Situ Phase Separation for 4D Printing
    Wang, Z.; Heck, M.; Yang, W.; Wilhelm, M.; Levkin, P. A.
    2024. Advanced Functional Materials, 34 (20), Art.-Nr.: 2300947. doi:10.1002/adfm.202300947 Full textFull text of the publication as PDF document