Publications 2025


  1. Design, synthesis, and computational studies of novel pyrazoline-based dual EGFR/HER-2 inhibitors with apoptotic antiproliferative activity
    Al-Wahaibi, L. H.; Hafez, H. M.; Edrees, F. H.; Abou-Zied, H. A.; Youssif, B. G. M.; Bräse, S.
    2025. Journal of Molecular Structure, 1339, 142364. doi:10.1016/j.molstruc.2025.142364
  2. A biofilm-targeting lipo-peptoid to treat Pseudomonas aeruginosa and Staphylococcus aureus co-infections
    Wardell, S. J. T.; Yung, D. B. Y.; Nielsen, J. E.; Lamichhane, R.; Sørensen, K.; Molchanova, N.; Herlan, C.; Lin, J. S.; Bräse, S.; Wise, L. M.; Barron, A. E.; Pletzer, D.
    2025. Biofilm, 9, 100272. doi:10.1016/j.bioflm.2025.100272Full textFull text of the publication as PDF document
  3. UV‐Induced Photopatterning of the Thermoresponsive Properties of a Poly(ethylene glycol)methylether acrylate‐co‐poly( N ‐isopropylacrylamide) Hydrogel
    Cheng, Q.-P.; Mandsberg, N. K.; Levkin, P. A.; Hsu, S.- hui
    2025. Small Structures, 6 (6), Art.-Nr.: 2400560. doi:10.1002/sstr.202400560Full textFull text of the publication as PDF document
  4. Unveiling the therapeutic potential of 1,2,4-oxadiazole derivatives: An updated review
    Khasawneh, H. E. N.; Alrikabi, A. A. A.; AL-Erjan, A. M.; Kadham, M. J.; Al-Aouadi, R. F. A.; Lakshmaiya, N.; Muhayyo, R.; Bräse, S.; Farhan, H. M.
    2025. Results in Chemistry, 15, 102271. doi:10.1016/j.rechem.2025.102271Full textFull text of the publication as PDF document
  5. Using the Chemotion repository to deposit and access FAIR research data for chemistry experiments
    Huang, P.-C.; Lin, C.-L.; Tremouilhac, P.; Jung, N.; Bräse, S.
    2025. Nature Protocols, 20 (5), 1097–1098. doi:10.1038/s41596-024-01074-z
  6. Nanoliter Hydrogel Array for Cell Screening and Cell Spheroid Sorting
    Salarian, M.; Levkin, P. A.; Popova, A. A.
    2025. Advanced Materials Technologies, 10 (8). doi:10.1002/admt.202401159Full textFull text of the publication as PDF document
  7. Silicon-organic hybrid (SOH) modulators for advanced photonic integration
    Freude, W.; Kotz, A.; Kholeif, H.; Schwarzenberger, A.; Kuzmin, A.; Eschenbaum, C.; Mertens, A.; Sarwar, S.; Erk, P.; Bräse, S.; Koos, C.
    2025. Optical Interconnects and Packaging 2025, SPIE. doi:10.1117/12.3039889
  8. Development and Application of Technologies for Liquid Manipulation on Droplet Microarrays. PhD dissertation
    Urrutia Gómez, J. E.
    2025, March 18. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000179833Full textFull text of the publication as PDF document
  9. Drug sensitivity and resistance test on a Droplet Microarray chip for solid types of tumors. PhD dissertation
    Salarian, M.
    2025, March 7. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000179348Full textFull text of the publication as PDF document
  10. Enhancing FAIRdata by providing digital workflows from data generation to the publication of data: an open source approach described for cyclic voltammetry
    Herrmann, D.; Hodapp, P.; Starman, M.; Huang, P.-C.; Lin, C.-L.; Le, L. B. Q.; Fischer, T. G.; Bizzarri, C.; Röse, P.; Oppel, N.; Klar, J.; Tremouilhac, P.; Holzhauer, L.; Herres-Pawlis, S.; Hoffmann, A.; Seitz, T.; Dorn, A.; Zeitler, K.; Jung, N.; Bräse, S.
    2025. Chemical Science, 16 (10), 4430–4441. doi:10.1039/d4sc08620aFull textFull text of the publication as PDF document
  11. Personalized Drug Response Profiling for Patient-Derived CLL cells via Miniaturized Gene Expression and Drug Sensitivity Testing on Droplet Microarray. PhD dissertation
    El Khaled El Faraj, R.
    2025, February 19. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000178982Full textFull text of the publication as PDF document
  12. Identification of novel triazolylquinoxaline-based metal complexes supported by experimental and virtual screenings
    Holzhauer, L.; Shekhovtsev, V.; Bruschi, C.; Gunther, M.; Fuhr, O.; Hodapp, P.; Bizzarri, C.; Wenzel, W.; Jung, N.; Bräse, S.
    2025. Dalton Transactions, 54 (8), 3287–3295. doi:10.1039/D4DT02068EFull textFull text of the publication as PDF document
  13. Functionalization of monolithic MOF thin films with hydrocarbon chains to achieve superhydrophobic surfaces with tunable water adhesion strength
    Bogdanova, E.; Liu, M.; Hodapp, P.; Borbora, A.; Wenzel, W.; Bräse, S.; Jung, A.; Dong, Z.; Levkin, P. A.; Manna, U.; Hashem, T.; Wöll, C.
    2025. Materials Horizons, 12 (4), 1274–1281. doi:10.1039/D4MH00899EFull textFull text of the publication as PDF document
  14. Droplet Microarrays for Miniaturized and High‐Throughput Experiments: Progress and Prospectives
    Kartsev, D. D.; Urrutia Gómez, J. E.; Anna, P. A.; Levkin, P. A.
    2025. Advanced Materials Interfaces, 12 (4), Art.-Nr.: 2400905. doi:10.1002/admi.202400905Full textFull text of the publication as PDF document
  15. Catalytic Syntheses of Pyrano[3,2-c]Quinolone and -Quinoline Derivatives and their Potential Therapeutic Agents
    Aly, A. A.; Abd El-Naby, H. A.; Ahmed, E. K.; Gedamy, S. A.; Alshammari, M. B.; Ahmad, A.; Bräse, S.
    2025. Current Organic Chemistry, 29 (3), 181–212. doi:10.2174/0113852728331472240826071320
  16. CD44 in myEloid cells is a major driver of liver inflammation and injury in alcohol-related liver disease
    Rousseau, D.; Bonnafous, S.; Soysouvanh, F.; Sarrail, D.; Bourinet, M.; Strazzulla, A.; Patouraux, S.; Borderie, A.; Dolfi, B.; Gallerand, A.; Farrugia, M. A.; Orian-rousseau, V.; Xu, Y.; Williams, J. W.; Ivanov, S.; Tran, A.; Anty, R.; Luci, C.; Gual, P.
    2025. Hepatology. doi:10.1097/HEP.0000000000001232
  17. Hyperphosphorescent OLEDs: Harnessing the Power of MR‐TADF Terminal Emitters
    Puttock, E. V.; Haug, J.; Zysman-Colman, E.; Bräse, S.
    2025. Advanced Optical Materials, 2500514. doi:10.1002/adom.202500514Full textFull text of the publication as PDF document
  18. Addressing standardization and semantics in an electronic lab notebook for multidisciplinary use: LabIMotion
    Lin, C.-L.; Huang, P.-C.; Wöll, C.; Théato, P.; Kübel, C.; Pilz, L.; Jung, N.; Bräse, S.
    2025. Journal of Cheminformatics, 17 (1), 75. doi:10.1186/s13321-025-01021-4Full textFull text of the publication as PDF document
  19. [2.2]Paracyclophane-substituted quinolines by skeletal editing strategies
    Köhler, T.; Fuhr, O.; Bräse, S.
    2025. Organic Chemistry Frontiers, 12, 3546–3550. doi:10.1039/D5QO00505AFull textFull text of the publication as PDF document
  20. Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors
    Al-Wahaibi, L. H.; Elshamsy, A. M.; Ali, T. F. S.; Youssif, B. G. M.; Bräse, S.; Abdel-Aziz, M.; El-Koussi, N. A.
    2025. Frontiers in Chemistry, 13, 1565699. doi:10.3389/fchem.2025.1565699Full textFull text of the publication as PDF document
  21. Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
    Samaridou, E.; Simon, J.; Beck-Broichsitter, M.; Davidson, G.; Levkin, P. A.
    2025. Advanced Healthcare Materials, 14 (15), 2501037. doi:10.1002/adhm.202501037Full textFull text of the publication as PDF document
  22. Chiral Polymers Based on Vinyl[2.2]paracyclophane and Their Application as CPL Emitters
    Tappert, H.; Puttock, E. V.; Oviedo Ortiz, J. S.; Zysman-Colman, E.; Crassous, J.; Bräse, S.
    2025. Polymers, 17 (8), 1070. doi:10.3390/polym17081070Full textFull text of the publication as PDF document
  23. Blue to yellow-emitting neutral Cu(I) complexes with μ-bridging 1,2,4-triazole: synthesis, photophysical characterization and DFT calculations
    Ferraro, V.; Gan, X.; Rehak, F. R.; Ralle, P.; Nieger, M.; Steffen, A.; Klopper, W.; Bräse, S.
    2025. New Journal of Chemistry. doi:10.1039/D5NJ01056JFull textFull text of the publication as PDF document
  24. Discovery of a novel 4-pyridyl SLC-0111 analog targeting tumor-associated carbonic anhydrase isoform IX through tail-based design approach with potent anticancer activity
    Hashem, H.; Abdelfattah, S.; Hassan, H. M.; Al-Emam, A.; Alqarni, M.; Alotaibi, G.; Radwan, I. T.; Kaur, K.; Rao, D. P.; Bräse, S.; Alkhammash, A.
    2025. Frontiers in Chemistry, 13, Art.-Nr.: 1571646. doi:10.3389/fchem.2025.1571646Full textFull text of the publication as PDF document
  25. Enhancing Optoelectronic Properties in Phthalocyanine‐Based SURMOFs: Synthesis of ABAB Linkers by Avoiding Statistical Condensation with Tailored Building Blocks
    Langer, L. S.; Stahlberger, M.; Liu, X.; Luo, Y.; Häußermann, N. E.; Singhvi, P.; Liu, Y.; Fuhr, O.; Nieger, M.; Heinke, L.; Heine, T.; Wöll, C.; Bräse, S.
    2025. Advanced Functional Materials, Art.-Nr.: 2421693. doi:10.1002/adfm.202421693Full textFull text of the publication as PDF document
  26. Design, Synthesis, and Antiproliferative Activity of Novel Indole/1,2,4-Triazole Hybrids as Tubulin Polymerization Inhibitors
    Mahmoud, E.; Abdelhamid, D.; Mohammed, A. F.; Almarhoon, Z. M.; Bräse, S.; Youssif, B. G. M.; Hayallah, A. M.; Abdel-Aziz, M.
    2025. Pharmaceuticals, 18 (2), 275. doi:10.3390/ph18020275Full textFull text of the publication as PDF document
  27. Infrared spectrum analysis of organic molecules with neural networks using standard reference data sets in combination with real-world data
    Punjabi, D.; Huang, Y.-C.; Holzhauer, L.; Tremouilhac, P.; Friederich, P.; Jung, N.; Bräse, S.
    2025. Journal of Cheminformatics, 17 (1), Art.-Nr.: 24. doi:10.1186/s13321-025-00960-2Full textFull text of the publication as PDF document
  28. Linking Research Data with Physically Preserved Research Materials in Chemistry
    Lin, C.-L.; Huang, P.-C.; Gräßle, S.; Grathwol, C.; Tremouilhac, P.; Vanderheiden, S.; Hodapp, P.; Herres-Pawlis, S.; Hoffmann, A.; Fink, F.; Manolikakes, G.; Opatz, T.; Link, A.; Marques, M. M. B.; Daumann, L. J.; Tsotsalas, M.; Biedermann, F.; Mutlu, H.; Täuscher, E.; Bach, F.; Drees, T.; Neumann, S.; Harivyasi, S. S.; Jung, N.; Bräse, S.
    2025. Scientific Data, 12 (1), Article no: 130. doi:10.1038/s41597-025-04404-2Full textFull text of the publication as PDF document
  29. An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024)
    Waseem, A. M.; Elmagzoub, R. M.; Abdelgadir, M. M. M.; Bahir, A. A.; EL-Gawaad, N. S. A.; Abdel-Samea, A. S.; Rao, D. P.; Kossenas, K.; Bräse, S.; Hashem, H.
    2025. Results in Chemistry, 13, 101989. doi:10.1016/j.rechem.2024.101989Full textFull text of the publication as PDF document
  30. Highly Parallel and High‐Throughput Nanoliter‐Scale Liquid, Cell, and Spheroid Manipulation on Droplet Microarray
    Urrutia Gómez, J. E.; Zhou, M.; Mandsberg, N. K.; Serna, J. A.; Padberg, J. von; Liu, S.; Reischl, M.; Levkin, P. A.; Popova, A. A.
    2025. Advanced Functional Materials, 35 (1), Art.-Nr.: 2410355. doi:10.1002/adfm.202410355Full textFull text of the publication as PDF document
  31. Drug‐Induced Differential Gene Expression Analysis on Nanoliter Droplet Microarrays: Enabling Tool for Functional Precision Oncology
    El Khaled EL Faraj, R.; Chakraborty, S.; Zhou, M.; Sobol, M.; Thiele, D.; Shatford-Adams, L. M.; Correa Cassal, M.; Kaster, A.-K.; Dietrich, S.; Levkin, P. A.; Popova, A. A.
    2025. Advanced Healthcare Materials, 14 (1), Art.-Nr.: 2401820. doi:10.1002/adhm.202401820Full textFull text of the publication as PDF document
  32. Zinc Phthalocyanine Core‐First Star Polymers Through Nitroxide Mediated Polymerization and Nitroxide Exchange Reaction
    Ahmetali, E.; Kocaarslan, A.; Bräse, S.; Théato, P.; Kasım Şener, M.
    2025. Macromolecular Rapid Communications, 46 (1), 2400601. doi:10.1002/marc.202400601Full textFull text of the publication as PDF document
  33. Omniphobic Photoresist-Assisted Patterning of Porous Polymethacrylate Films
    Kartsev, D. D.; Lukianov, I. M.; Sharapenkov, E. G.; Prilepskii, A. Y.; Levkin, P. A.
    2025. Advanced materials interfaces, 12 (1), Art.-Nr.: 2400569. doi:10.1002/admi.202400569Full textFull text of the publication as PDF document