Publications 2025


  1. Design, synthesis, and antiproliferative activity of new 5-ethylsulfonyl-indazole-3-carbohydrazides as dual EGFR/VEGFR-2 kinases inhibitors
    Al-Wahaibi, L. H.; Abou-Zied, H. A.; Mahmoud, M. A.; Youssif, B. G. M.; Bräse, S.; Rabea, S. M.
    2025. Journal of Enzyme Inhibition and Medicinal Chemistry, 40, Article no: 2516075. doi:10.1080/14756366.2025.2516075 Full textFull text of the publication as PDF document 
  2. Design, synthesis, and computational studies of novel pyrazoline-based dual EGFR/HER-2 inhibitors with apoptotic antiproliferative activity
    Al-Wahaibi, L. H.; Hafez, H. M.; Edrees, F. H.; Abou-Zied, H. A.; Youssif, B. G. M.; Bräse, S.
    2025. Journal of Molecular Structure, 1339, 142364. doi:10.1016/j.molstruc.2025.142364 
  3. TADF Copper(I) Complexes – from Synthesis to Application in OLEDs and 3D Laser Nanoprinting. PhD dissertation
    Adam, C. R.
    2025, July 31. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000183269 
  4. Blue to yellow-emitting neutral Cu(I) complexes with μ-bridging 1,2,4-triazole: synthesis, photophysical characterization and DFT calculations
    Ferraro, V.; Gan, X.; Rehak, F. R.; Ralle, P.; Nieger, M.; Steffen, A.; Klopper, W.; Bräse, S.
    2025. New Journal of Chemistry, 49 (29), 12468–12475. doi:10.1039/D5NJ01056J Full textFull text of the publication as PDF document 
  5. Advances in the modification and applications of cellulosic-based materials for wastewater remediation: a review
    Nayl, A. A.; Abd-Elhamid, A. I.; Mosnáčková, K.; Arafa, W. A. A.; Alanazi, A. H.; Ahmed, I. M.; Ali, H. M.; Aly, A. A.; Akl, M. A.; Doma, A. S.; Aly, H. F.; Bräse, S.
    2025. Applied Water Science, 15 (7), Articlen no: 177. doi:10.1007/s13201-025-02498-y Full textFull text of the publication as PDF document 
  6. A biofilm-targeting lipo-peptoid to treat Pseudomonas aeruginosa and Staphylococcus aureus co-infections
    Wardell, S. J. T.; Yung, D. B. Y.; Nielsen, J. E.; Lamichhane, R.; Sørensen, K.; Molchanova, N.; Herlan, C.; Lin, J. S.; Bräse, S.; Wise, L. M.; Barron, A. E.; Pletzer, D.
    2025. Biofilm, 9, 100272. doi:10.1016/j.bioflm.2025.100272 Full textFull text of the publication as PDF document 
  7. UV‐Induced Photopatterning of the Thermoresponsive Properties of a Poly(ethylene glycol)methylether acrylate‐co‐poly( N ‐isopropylacrylamide) Hydrogel
    Cheng, Q.-P.; Mandsberg, N. K.; Levkin, P. A.; Hsu, S.- hui
    2025. Small Structures, 6 (6), Art.-Nr.: 2400560. doi:10.1002/sstr.202400560 Full textFull text of the publication as PDF document 
  8. Unveiling the therapeutic potential of 1,2,4-oxadiazole derivatives: An updated review
    Khasawneh, H. E. N.; Alrikabi, A. A. A.; AL-Erjan, A. M.; Kadham, M. J.; Al-Aouadi, R. F. A.; Lakshmaiya, N.; Muhayyo, R.; Bräse, S.; Farhan, H. M.
    2025. Results in Chemistry, 15, 102271. doi:10.1016/j.rechem.2025.102271 Full textFull text of the publication as PDF document 
  9. Using the Chemotion repository to deposit and access FAIR research data for chemistry experiments
    Huang, P.-C.; Lin, C.-L.; Tremouilhac, P.; Jung, N.; Bräse, S.
    2025. Nature Protocols, 20 (5), 1097–1098. doi:10.1038/s41596-024-01074-z 
  10. Nanoliter Hydrogel Array for Cell Screening and Cell Spheroid Sorting
    Salarian, M.; Levkin, P. A.; Popova, A. A.
    2025. Advanced Materials Technologies, 10 (8). doi:10.1002/admt.202401159 Full textFull text of the publication as PDF document 
  11. Silicon-organic hybrid (SOH) modulators for advanced photonic integration
    Freude, W.; Kotz, A.; Kholeif, H.; Schwarzenberger, A.; Kuzmin, A.; Eschenbaum, C.; Mertens, A.; Sarwar, S.; Erk, P.; Bräse, S.; Koos, C.
    2025. Optical Interconnects and Packaging 2025, SPIE. doi:10.1117/12.3039889 
  12. Development and Application of Technologies for Liquid Manipulation on Droplet Microarrays. PhD dissertation
    Urrutia Gómez, J. E.
    2025, March 18. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000179833 Full textFull text of the publication as PDF document 
  13. Drug sensitivity and resistance test on a Droplet Microarray chip for solid types of tumors. PhD dissertation
    Salarian, M.
    2025, March 7. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000179348 Full textFull text of the publication as PDF document 
  14. Enhancing FAIRdata by providing digital workflows from data generation to the publication of data: an open source approach described for cyclic voltammetry
    Herrmann, D.; Hodapp, P.; Starman, M.; Huang, P.-C.; Lin, C.-L.; Le, L. B. Q.; Fischer, T. G.; Bizzarri, C.; Röse, P.; Oppel, N.; Klar, J.; Tremouilhac, P.; Holzhauer, L.; Herres-Pawlis, S.; Hoffmann, A.; Seitz, T.; Dorn, A.; Zeitler, K.; Jung, N.; Bräse, S.
    2025. Chemical Science, 16 (10), 4430–4441. doi:10.1039/d4sc08620a Full textFull text of the publication as PDF document 
  15. Personalized Drug Response Profiling for Patient-Derived CLL cells via Miniaturized Gene Expression and Drug Sensitivity Testing on Droplet Microarray. PhD dissertation
    El Khaled El Faraj, R.
    2025, February 19. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000178982 Full textFull text of the publication as PDF document 
  16. Identification of novel triazolylquinoxaline-based metal complexes supported by experimental and virtual screenings
    Holzhauer, L.; Shekhovtsev, V.; Bruschi, C.; Gunther, M.; Fuhr, O.; Hodapp, P.; Bizzarri, C.; Wenzel, W.; Jung, N.; Bräse, S.
    2025. Dalton Transactions, 54 (8), 3287–3295. doi:10.1039/D4DT02068E Full textFull text of the publication as PDF document 
  17. Functionalization of monolithic MOF thin films with hydrocarbon chains to achieve superhydrophobic surfaces with tunable water adhesion strength
    Bogdanova, E.; Liu, M.; Hodapp, P.; Borbora, A.; Wenzel, W.; Bräse, S.; Jung, A.; Dong, Z.; Levkin, P. A.; Manna, U.; Hashem, T.; Wöll, C.
    2025. Materials Horizons, 12 (4), 1274–1281. doi:10.1039/D4MH00899E Full textFull text of the publication as PDF document 
  18. Droplet Microarrays for Miniaturized and High‐Throughput Experiments: Progress and Prospectives
    Kartsev, D. D.; Urrutia Gómez, J. E.; Anna, P. A.; Levkin, P. A.
    2025. Advanced Materials Interfaces, 12 (4), Art.-Nr.: 2400905. doi:10.1002/admi.202400905 Full textFull text of the publication as PDF document 
  19. Catalytic Syntheses of Pyrano[3,2-c]Quinolone and -Quinoline Derivatives and their Potential Therapeutic Agents
    Aly, A. A.; Abd El-Naby, H. A.; Ahmed, E. K.; Gedamy, S. A.; Alshammari, M. B.; Ahmad, A.; Bräse, S.
    2025. Current Organic Chemistry, 29 (3), 181–212. doi:10.2174/0113852728331472240826071320 
  20. CD44 in myEloid cells is a major driver of liver inflammation and injury in alcohol-related liver disease
    Rousseau, D.; Bonnafous, S.; Soysouvanh, F.; Sarrail, D.; Bourinet, M.; Strazzulla, A.; Patouraux, S.; Borderie, A.; Dolfi, B.; Gallerand, A.; Farrugia, M. A.; Orian-rousseau, V.; Xu, Y.; Williams, J. W.; Ivanov, S.; Tran, A.; Anty, R.; Luci, C.; Gual, P.
    2025. Hepatology. doi:10.1097/HEP.0000000000001232 
  21. Implementation of an open chemistry knowledge base with a Semantic Wiki
    Neidiger, C.; Saier, T.; Kühn, K.; Larignon, V.; Färber, M.; Bizzarri, C.; Šimek Tosino, H.; Holzhauer, L.; Erdmann, M.; Nguyen, A.; Harvey, D.; Tremouilhac, P.; Kramer, C.; Hansch, D.; Schönle, F.; Alpin, J.; Hartmann, M.; Wagner, J.; Jung, N.; Bräse, S.
    2025. Journal of Cheminformatics, 17 (1), Article no: 99. doi:10.1186/s13321-025-01037-w Full textFull text of the publication as PDF document 
  22. Quantification of Wnt3a, Wnt5a and Wnt16 Binding to Multiple Frizzleds Under Physiological Conditions Using NanoBit/BRET
    Wesslowski, J.; Safi, S.; Rottmann, M.; Rothley, M.; Davidson, G.
    2025. Cells, 14 (11), Article no: 810. doi:10.3390/cells14110810 Full textFull text of the publication as PDF document 
  23. ELNdataBridge: facilitating data exchange and collaboration by linking Electronic Lab Notebooks via API
    Starman, M.; Kirchner, F.; Held, M.; Eschke, C.; Sahim, S.-A.; Willumeit-Römer, R.; Jung, N.; Bräse, S.
    2025. Journal of Cheminformatics, 17 (1), Article no: 86. doi:10.1186/s13321-025-01024-1 Full textFull text of the publication as PDF document 
  24. Design, synthesis, and biological investigation of new thiazole-based derivatives as multi-targeted inhibitors endowed with antiproliferative, antioxidant, and antibacterial properties
    Gomaa, H. A. M.; Atta, A. M.; Shaker, M. E.; Alzarea, S. I.; Alsahli, T. G.; Alatwi, E.; Musa, A.; Mohamed, F. A. M.; Alzahrani, H. A.; Mohassab, A. M.; Abdelmoez, A.; Bräse, S.; Youssif, B. G. M.
    2025. Frontiers in Chemistry, 13, 1595997. doi:10.3389/fchem.2025.1595997 Full textFull text of the publication as PDF document 
  25. Hyperphosphorescent OLEDs: Harnessing the Power of MR‐TADF Terminal Emitters
    Puttock, E. V.; Haug, J.; Zysman-Colman, E.; Bräse, S.
    2025. Advanced Optical Materials, 2500514. doi:10.1002/adom.202500514 Full textFull text of the publication as PDF document 
  26. Addressing standardization and semantics in an electronic lab notebook for multidisciplinary use: LabIMotion
    Lin, C.-L.; Huang, P.-C.; Wöll, C.; Théato, P.; Kübel, C.; Pilz, L.; Jung, N.; Bräse, S.
    2025. Journal of Cheminformatics, 17 (1), 75. doi:10.1186/s13321-025-01021-4 Full textFull text of the publication as PDF document 
  27. [2.2]Paracyclophane-substituted quinolines by skeletal editing strategies
    Köhler, T.; Fuhr, O.; Bräse, S.
    2025. Organic Chemistry Frontiers, 12, 3546–3550. doi:10.1039/D5QO00505A Full textFull text of the publication as PDF document 
  28. Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors
    Al-Wahaibi, L. H.; Elshamsy, A. M.; Ali, T. F. S.; Youssif, B. G. M.; Bräse, S.; Abdel-Aziz, M.; El-Koussi, N. A.
    2025. Frontiers in Chemistry, 13, 1565699. doi:10.3389/fchem.2025.1565699 Full textFull text of the publication as PDF document 
  29. Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
    Samaridou, E.; Simon, J.; Beck-Broichsitter, M.; Davidson, G.; Levkin, P. A.
    2025. Advanced Healthcare Materials, 14 (15), 2501037. doi:10.1002/adhm.202501037 Full textFull text of the publication as PDF document 
  30. Chiral Polymers Based on Vinyl[2.2]paracyclophane and Their Application as CPL Emitters
    Tappert, H.; Puttock, E. V.; Oviedo Ortiz, J. S.; Zysman-Colman, E.; Crassous, J.; Bräse, S.
    2025. Polymers, 17 (8), 1070. doi:10.3390/polym17081070 Full textFull text of the publication as PDF document 
  31. Discovery of a novel 4-pyridyl SLC-0111 analog targeting tumor-associated carbonic anhydrase isoform IX through tail-based design approach with potent anticancer activity
    Hashem, H.; Abdelfattah, S.; Hassan, H. M.; Al-Emam, A.; Alqarni, M.; Alotaibi, G.; Radwan, I. T.; Kaur, K.; Rao, D. P.; Bräse, S.; Alkhammash, A.
    2025. Frontiers in Chemistry, 13, Art.-Nr.: 1571646. doi:10.3389/fchem.2025.1571646 Full textFull text of the publication as PDF document 
  32. Enhancing Optoelectronic Properties in Phthalocyanine‐Based SURMOFs: Synthesis of ABAB Linkers by Avoiding Statistical Condensation with Tailored Building Blocks
    Langer, L. S.; Stahlberger, M.; Liu, X.; Luo, Y.; Häußermann, N. E.; Singhvi, P.; Liu, Y.; Fuhr, O.; Nieger, M.; Heinke, L.; Heine, T.; Wöll, C.; Bräse, S.
    2025. Advanced Functional Materials, Art.-Nr.: 2421693. doi:10.1002/adfm.202421693 Full textFull text of the publication as PDF document 
  33. Design, Synthesis, and Antiproliferative Activity of Novel Indole/1,2,4-Triazole Hybrids as Tubulin Polymerization Inhibitors
    Mahmoud, E.; Abdelhamid, D.; Mohammed, A. F.; Almarhoon, Z. M.; Bräse, S.; Youssif, B. G. M.; Hayallah, A. M.; Abdel-Aziz, M.
    2025. Pharmaceuticals, 18 (2), 275. doi:10.3390/ph18020275 Full textFull text of the publication as PDF document 
  34. Infrared spectrum analysis of organic molecules with neural networks using standard reference data sets in combination with real-world data
    Punjabi, D.; Huang, Y.-C.; Holzhauer, L.; Tremouilhac, P.; Friederich, P.; Jung, N.; Bräse, S.
    2025. Journal of Cheminformatics, 17 (1), Art.-Nr.: 24. doi:10.1186/s13321-025-00960-2 Full textFull text of the publication as PDF document 
  35. Linking Research Data with Physically Preserved Research Materials in Chemistry
    Lin, C.-L.; Huang, P.-C.; Gräßle, S.; Grathwol, C.; Tremouilhac, P.; Vanderheiden, S.; Hodapp, P.; Herres-Pawlis, S.; Hoffmann, A.; Fink, F.; Manolikakes, G.; Opatz, T.; Link, A.; Marques, M. M. B.; Daumann, L. J.; Tsotsalas, M.; Biedermann, F.; Mutlu, H.; Täuscher, E.; Bach, F.; Drees, T.; Neumann, S.; Harivyasi, S. S.; Jung, N.; Bräse, S.
    2025. Scientific Data, 12 (1), Article no: 130. doi:10.1038/s41597-025-04404-2 Full textFull text of the publication as PDF document 
  36. An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024)
    Waseem, A. M.; Elmagzoub, R. M.; Abdelgadir, M. M. M.; Bahir, A. A.; EL-Gawaad, N. S. A.; Abdel-Samea, A. S.; Rao, D. P.; Kossenas, K.; Bräse, S.; Hashem, H.
    2025. Results in Chemistry, 13, 101989. doi:10.1016/j.rechem.2024.101989 Full textFull text of the publication as PDF document 
  37. Highly Parallel and High‐Throughput Nanoliter‐Scale Liquid, Cell, and Spheroid Manipulation on Droplet Microarray
    Urrutia Gómez, J. E.; Zhou, M.; Mandsberg, N. K.; Serna, J. A.; Padberg, J. von; Liu, S.; Reischl, M.; Levkin, P. A.; Popova, A. A.
    2025. Advanced Functional Materials, 35 (1), Art.-Nr.: 2410355. doi:10.1002/adfm.202410355 Full textFull text of the publication as PDF document 
  38. Drug‐Induced Differential Gene Expression Analysis on Nanoliter Droplet Microarrays: Enabling Tool for Functional Precision Oncology
    El Khaled EL Faraj, R.; Chakraborty, S.; Zhou, M.; Sobol, M.; Thiele, D.; Shatford-Adams, L. M.; Correa Cassal, M.; Kaster, A.-K.; Dietrich, S.; Levkin, P. A.; Popova, A. A.
    2025. Advanced Healthcare Materials, 14 (1), Art.-Nr.: 2401820. doi:10.1002/adhm.202401820 Full textFull text of the publication as PDF document 
  39. Zinc Phthalocyanine Core‐First Star Polymers Through Nitroxide Mediated Polymerization and Nitroxide Exchange Reaction
    Ahmetali, E.; Kocaarslan, A.; Bräse, S.; Théato, P.; Kasım Şener, M.
    2025. Macromolecular Rapid Communications, 46 (1), 2400601. doi:10.1002/marc.202400601 Full textFull text of the publication as PDF document 
  40. Omniphobic Photoresist-Assisted Patterning of Porous Polymethacrylate Films
    Kartsev, D. D.; Lukianov, I. M.; Sharapenkov, E. G.; Prilepskii, A. Y.; Levkin, P. A.
    2025. Advanced materials interfaces, 12 (1), Art.-Nr.: 2400569. doi:10.1002/admi.202400569 Full textFull text of the publication as PDF document