Andrew C. Cato - Publikationsliste
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Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
Neeb, A.; Figueiredo, I.; Bogdan, D.; Cato, L.; Stober, J.; Jiménez-Vacas, J. M.; Gourain, V.; Lee, I. I.; Seeger, R.; Muhle-Goll, C.; Gurel, B.; Welti, J.; Nava Rodrigues, D.; Rekowski, J.; Qiu, X.; Jiang, Y.; Di Micco, P.; Mateos, B.; Bielskutė, S.; Riisnaes, R.; Ferreira, A.; Miranda, S.; Crespo, M.; Buroni, L.; Ning, J.; Carreira, S.; Bräse, S.; Jung, N.; Gräßle, S.; Swain, A.; Salvatella, X.; Plymate, S. R.; Al-Lazikani, B.; Long, H. W.; Yuan, W.; Brown, M.; Cato, A. C. B.; de Bono, J. S.; Sharp, A.
2024. Molecular Cancer Therapeutics, 23 (6), 791–808. doi:10.1158/1535-7163.MCT-23-0354 -
Development and Validation of a New BAG-1L–Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer
Neeb, A.; Figueiredo, I.; Gurel, B.; Nava Rodrigues, D.; Rekowski, J.; Riisnaes, R.; Ferreira, A.; Miranda, S.; Crespo, M.; Westaby, D.; de Los Dolores Fenor de La Maza, M.; Guo, C.; Carmichael, J.; Grochot, R.; Tunariu, N.; Cato, A. C. B.; Plymate, S. R.; de Bono, J. S.; Sharp, A.
2023. Laboratory Investigation, 103 (11), Article no: 100245. doi:10.1016/j.labinv.2023.100245 -
Identification of an imidazopyridine-based compound as an oral selective estrogen receptor degrader for breast cancer therapy
Pan, M.; Solozobova, V.; Kuznik, N. C.; Jung, N.; Graessle, S.; Gourain, V.; Heneka, Y. M.; Cramer von Clausbruch, C. A.; Fuhr, O.; Munuganti, R. S. N.; Maddalo, D.; Blattner, C.; Neeb, A.; Sharp, A.; Cato, L.; Weiss, C.; Jeselsohn, R. M.; Orian-Rousseau, V.; Bräse, S.; Cato, A. C. B.
2023. Cancer Research Communications, 3 (7), 1378–1396. doi:10.1158/2767-9764.CRC-23-0111 -
A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway
Kuznik, N. C.; Solozobova, V.; Lee, I. I.; Jung, N.; Yang, L.; Nienhaus, K.; Ntim, E. A.; Rottenberg, J. T.; Muhle-Goll, C.; Kumar, A. R.; Peravali, R.; Gräßle, S.; Gourain, V.; Deville, C.; Cato, L.; Neeb, A.; Dilger, M.; Cramer von Clausbruch, C. A.; Weiss, C.; Kieffer, B.; Nienhaus, G. U.; Brown, M.; Bräse, S.; Cato, A. C. B.
2022. iScience, 25 (5), Art.Nr. 104175. doi:10.1016/j.isci.2022.104175 -
Development of a Benzothiazole Scaffold-Based Androgen Receptor N-Terminal Inhibitor for Treating Androgen-Responsive Prostate Cancer
Kuznik, N. C.; Solozobova, V.; Jung, N.; Gräßle, S.; Lei, Q.; Lewandowski, E. M.; Munuganti, R.; Zoubeidi, A.; Chen, Y.; Bräse, S.; Cato, A. C. B.
2021. ACS Chemical Biology, 16 (11), 2103–2108. doi:10.1021/acschembio.1c00390 -
BAG1L: a promising therapeutic target for androgen receptor-dependent prostate cancer
Lee, I. I.; Kuznik, N. C.; Rottenberg, J. T.; Brown, M.; Cato, A. C. B.
2019. Journal of molecular endocrinology, 62 (4), R289–R299. doi:10.1530/JME-19-0034 -
Regulation of the pleiotropic effects of tissue-resident mast cells
Huber, M.; Cato, A. C. B.; Ainooson, G. K.; Freichel, M.; Tsvilovskyy, V.; Jessberger, R.; Riedlinger, E.; Sommerhoff, C. P.; Bischoff, S. C.
2019. The journal of allergy and clinical immunology, 144 (4, SI), S31-S45. doi:10.1016/j.jaci.2019.02.004 -
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
Cato, L.; Tribolet-Hardy, J. de; Lee, I.; Rottenberg, J. T.; Coleman, I.; Melchers, D.; Houtman, R.; Xiao, T.; Li, W.; Uo, T.; Sun, S.; Kuznik, N. C.; Göppert, B.; Ozgun, F.; Royen, M. E. van; Houtsmuller, A. B.; Vadhi, R.; Rao, P. K.; Li, L.; Balk, S. P.; Den, R. B.; Trock, B. J.; Karnes, R. J.; Jenkins, R. B.; Klein, E. A.; Davicioni, E.; Gruhl, F. J.; Long, H. W.; Liu, X. S.; Cato, A. C. B.; Lack, N. A.; Nelson, P. S.; Plymate, S. R.; Groner, A. C.; Brown, M.
2019. Cancer cell, 35 (3), 401–413.e6. doi:10.1016/j.ccell.2019.01.008 -
Transcriptomic data on the role of PEST-domain-enriched tyrosine phosphatase in the regulation of antigen-mediated activation and antiallergic action of glucocorticoids in mast cells
Ainooson, G. K.; Gourain, V.; Stassen, M.; Cato, A. C. B.
2018. Data in Brief, 20, 1177–1183. doi:10.1016/j.dib.2018.08.188 -
Tripartite Motif Proteins-A Protein Family Strongly Linked to Cancer
Elabd, S.; Cato, A. C. B.; Blattner, C.
2017. Annals of Pharmacology and Pharmaceutics, 2 (10), 1–5 -
Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer
Cato, L.; Neeb, A.; Sharp, A.; Buzón, V.; Ficarro, S. B.; Yang, L.; Muhle-Goll, C.; Kuznik, N. C.; Riisnaes, R.; Rodrigues, D. N.; Armant, O.; Gourain, V.; Adelmant, G.; Ntim, E. A.; Westerling, T.; Dolling, D.; Rescigno, P.; Figueiredo, I.; Fauser, F.; Wu, J.; Rottenberg, J. T.; Shatkina, L.; Ester, C.; Luy, B.; Puchta, H.; Troppmair, J.; Jung, N.; Bräse, S.; Strähle, U.; Marto, J. A.; Nienhaus, G. U.; Al-Lazikani, B.; Salvatella, X.; Bono, J. S. de; Cato, A. C. B.; Brown, M.
2017. eLife, 6, Art.Nr. e27159. doi:10.7554/eLife.27159 -
An Amyloidogenic Sequence at the N-Terminus of the Androgen Receptor Impacts Polyglutamine Aggregation
Oppong, E.; Stier, G.; Gaal, M.; Seeger, R.; Stoeck, M.; Delsuc, M.-A.; Cato, A. C. B.; Kieffer, B.
2017. Biomolecules, 7 (2), 44. doi:10.3390/biom7020044 -
Polymer pen lithography for biosensing and biomedical applications
Hirtz, M.; Kumar, R.; Bog, U.; Sekula-Neuner, S.; Liu, H. Y.; Pantel, K.; Cato, A. C. B.; Fuchs, H.
2016. NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application; Hotel Voronez IBrno; Czech Republic; 19 October 2016 through 21 October 2016, 408–413, TANGER Ltd -
Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy
Polanco, M. J.; Parodi, S.; Piol, D.; Stack, C.; Chivet, M.; Contestabile, A.; Miranda, H. C.; Lievens, P. M.-J.; Espinoza, S.; Jochum, T.; Rocchi, A.; Grunseich, C.; Gainetdinov, R. R.; Cato, A. C. B.; Lieberman, A. P.; La Spada, A. R.; Sambataro, F.; Fischbeck, K. H.; Gozes, I.; Pennuto, M.
2016. Science translational medicine, 8 (370), 370ra181. doi:10.1126/scitranslmed.aaf9526 -
Click-Chemistry Based Allergen Arrays Generated by Polymer Pen Lithography for Mast Cell Activation Studies
Kumar, R.; Bonicelli, A.; Sekula-Neuner, S.; Cato, A. C. B.; Hirtz, M.; Fuchs, H.
2016. Small, 12 (38), 5330–5338. doi:10.1002/smll.201601623 -
TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer
Groner, A.; Cato, L.; Tribolet-Hardy, J. de; Bernasocchi, T.; Janouskova, H.; Melchers, D.; Houtman, R.; Cato, A.; Tschopp, P.; Gu, L.; Corsinotti, A.; Zhong, Q.; Fankhauser, C.; Fritz, C.; Poyet, C.; Wagner, U.; Guo, T.; Aebersold, R.; Garraway, L.; Wild, P. J.; Theurillat, J.-P.; Brown, M.
2016. Cancer cell, 29 (6), 846–858. doi:10.1016/j.ccell.2016.04.012 -
Superporous Poly(ethylene glycol) Diacrylate Cryogel with a Defined Elastic Modulus for Prostate Cancer Cell Research
Göppert, B.; Sollich, T.; Abaffy, P.; Cecilia, A.; Heckmann, J.; Neeb, A.; Bäcker, A.; Baumbach, T.; Gruhl, F. J.; Cato, A. C. B.
2016. Small, 12 (29), 3985–3994. doi:10.1002/smll.201600683 -
Abstract 4677: Control of androgen receptor function by the genomic action of the cochaperone Bag-1L
Cato, L.; Neeb, A.; Adelmant, G.; Ficarro, S.; Westerling, T.; Marto, J. A.; Cato, A. C.; Brown, M.
2015. Cancer research, 75 (15, Supplement), Art. Nr.: 4677. doi:10.1158/1538-7445.AM2015-4677 -
Effects of glucocorticoids in the immune system
Oppong, E.; Cato, A. C. B.
2015. Advances in experimental medicine and biology, 872, 217–233. doi:10.1007/978-1-4939-2895-8_9 -
Coregulator Control of Androgen Receptor Action by a Novel Nuclear Receptor-Binding Motif
Jehle, K.; Cato, L.; Neeb, A.; Muhle-Goll, C.; Jung, N.; Smith, E. W.; Buzon, V.; Carbo, L. R.; Estebanez-Perpina, E.; Schmitz, K.; Fruk, L.; Luy, B.; Chen, Y.; Cox, M. B.; Bräse, S.; Brown, M.; Cato, A. C. B.
2014. Journal of biological chemistry, 289 (13), 8839–8851. doi:10.1074/jbc.M113.534859 -
Analysis of the conformation of the androgen receptor in spinal bulbar muscular atrophy by atomic force microscopy
Jochum, T.; Cato, A. C. B.
2014. Castoria, G. [Hrsg.] Steoid Receptors : Methods and Protocols New York, N.Y. : Springer Science and Business Media, 2014 (Methods in Molecular Biology ; 1204), 197–204 -
Splice variant transcripts of the anterior gradient 2 gene as a marker of prostate cancer
Neeb, A.; Hefele, S.; Bormann, S.; Parson, W.; Adams, F.; Wolf, P.; Miernik, A.; Schoenthaler, M.; Kroenig, M.; Wilhelm, K.; Schultze-Seemann, W.; Nestel, S.; Schaefer, G.; Bu, H.; Klocker, H.; Nazarenko, I.; Cato, A. C. B.
2014. OncoTarget, 5 (18), 8681–8689. doi:10.18632/oncotarget.2365 -
Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L
Cato, L.; Neeb, A.; Brown, M.; Cato, A. C. B.
2014. Nuclear receptor signaling, 12, e005/1–15. doi:10.1621/nrs.12005 -
Formation of pathologic oligomers in SBMA
Jochum, T.; Brinkmann, F.; Ritz, M. E.; Bauer, M.; Moss, D. A.; Cato, A. C. B.
2014. 22nd Annual Meeting of the Israel Society for Neuroscience (ISFN) and 2nd Binational Italy-Israel Neuroscience Meeting, Eilat, IL, December 14-17, 2013 Journal of Molecular Neuroscience, 53(2014) Suppl.1, (Abstract), 2nd Annual Meeting of the Israel Society for Neuroscience (ISFN) and 2nd Binational Italy-Israel Neuroscience Meeting (2013), Eilat, Israel, 14.–17. Dezember 2013 -
Localization and Dynamics of Glucocorticoid Receptor at the Plasma Membrane of Activated Mast Cells
Oppong, E.; Hedde, P. N.; Sekula-Neuner, S.; Yang, L.; Brinkmann, F.; Dörlich, R. M.; Hirtz, M.; Fuchs, H.; Nienhaus, G. U.; Cato, A. C. B.
2014. Small, 10 (10), 1991–1998. doi:10.1002/smll.201303677 -
Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis
Bruchmann, A.; Roller, C.; Walther, T. V.; Schäfer, G.; Lehmusvaara, S.; Visakorpi, T.; Klocker, H.; Cato, A. C. B.; Maddalo, D.
2013. BMC Cancer, 13, 96. doi:10.1186/1471-2407-13-96 -
Stimulated emission depletion-based raster image correlation spectroscopy reveals biomolecular dynamics in live cells
Hedde, P. N.; Dörlich, R. M.; Blomley, R.; Gradl, D.; Oppong, E.; Cato, A. C. B.; Nienhaus, G. U.
2013. Nature Communications, 4, 2093. doi:10.1038/ncomms3093 -
The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells
Kullmann, M. K.; Grubbauer, C.; Goetsch, K.; Jäkel, H.; Podmirseg, S. R.; Trockenbacher, A.; Ploner, C.; Cato, A. C. B.; Weiss, C.; Kofler, R.; Hengst, L.
2013. Cell Cycle, 12, 2625–2635. doi:10.4161/cc.25622 -
’SEGRAs’ and beyond
Cato, A. C. B.
2013. Molecular and Cellular Endocrinology, 380, 1. doi:10.1016/j.mce.2013.06.011 -
Molecular mechanisms of glucocorticoid action in mast cells
Oppong, E.; Flink, N.; Cato, A. C. B.
2013. Molecular and Cellular Endocrinology, 380, 119–126. doi:10.1016/j.mce.2013.05.014 -
Membrane localization of glucocorticoid receptor in mast cells activated on allergen arrays
Sekula-Neuner, S.; Oppong, E.; Hedde, P. N.; Nienhaus, G. U.; Cato, A. C. B.; Fuchs, H.
2013. International Mastcell and Basophil Meeting, Udine, I, August 28-30, 2013 -
Enhanced inhibition of prostate tumor growth by dual targeting the androgen receptor and the regulatory subunit type Iα of protein kinase A in vivo
Eder, I. E.; Egger, M.; Neuwirt, H.; Seifarth, C.; Maddalo, D.; Desiniotis, A.; Schäfer, G.; Puhr, M.; Bektic, J.; Cato, A. C. B.; Klocker, H.
2013. International Journal of Molecular Sciences, 14, 11942–11962. doi:10.3390/ijms140611942 -
A potent and selective small molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune deseases
He, Y.; Liu, S.; Menon, A.; Stanford, S. M.; Oppong, E.; Gunawan, A. M.; Wu, L.; Wu, D. J.; Barrios, A. M.; Bottini, N.; Cato, A. C. B.; Zhang, Z. Y.
2013. Journal of Medicinal Chemistry, 56, 4990–5008. doi:10.1021/jm400248c -
Anterior gradient 2 and 3 - two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells
Bu, H.; Schweiger, M. R.; Manke, T.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Pasqualini, L.; Shehu, E.; Fuchsberger, C.; Cato, A. C. B.; Klocker, H.
2013. FEBS Journal, 280, 1249–1266. doi:10.1111/febs.12118 -
Magnetic heating effect of nanoparticles with different sizes and size distributions
Müller, R.; Dutz, S.; Neeb, A.; Cato, A. C. B.; Zeisberger, M.
2013. Journal of Magnetism and Magnetic Materials, 328, 80–85. doi:10.1016/j.jmmm.2012.09.064 -
A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death
Maddalo, D.; Neeb, A.; Jehle, K.; Schmitz, K.; Muhle-Goll, C.; Shatkina, L.; Walther, T. V.; Bruchmann, A.; Gopal, S. M.; Wenzel, W.; Ulrich, A. S.; Cato, A. C. B.
2012. PLoS one, 7 (10), Art.Nr. e45690. doi:10.1371/journal.pone.0045690 -
Micropatterned surfaces as tools for the study of the rapid non-genomic actions of steroid receptors
Cato, A. C. B.; Oppong, E.; Sekula-Neuner, S.
2012. Castoria, G. [Hrsg.] Advances in Rapid Sex-Steroid Action : New Challenges and New Chances in Breast and Prosate Cancers New York, N.Y [u.a.] : Springer Science and Business Media, 2012, 253–266 -
Knockout of Mkp-1 exacerbates colitis in Il-10-deficient mice
Matta, R.; Barnard, J. A.; Wancket, L. M.; Yan, J.; Xue, J.; Grieves, J.; Frazier, W. J.; Nelin, L.; Cato, A. C. B.; Liu, Y.
2012. American Journal of Physiology - Gastrointestinal and Liver Physiology, 302, G1322-G1335. doi:10.1152/ajpgi.00018.2012 -
The Bcl-2 associated athanogene 5 inhibits stress induces apoptosis and enhances chemoresistance in prostate cancer cells
Bruchmann, A.; Roller, C.; Walther, T. V.; Cato, A. C. B.; Maddalo, D.
2012. Molecularly Targeted Therapies: Mechanisms of Resistance, San Diego, Calif., May 9-12, 2012 Clinical Cancer Research, 18(2012) No.10 Suppl., A62 (Abstract). doi:10.1158/1078-0432.MECHRES-A62 -
What is a name? [Editorial]
Cato, A. C. B.; Fuller, P. J.
2012. Molecular and Cellular Endocrinology, 350 (2), 145. doi:10.1016/j.mce.2011.08.011 -
Allergen arrays for antibody screening and immune cell activation profiling generated by parallel lipid dip-pen nanolithography
Sekula-Neuner, S.; Maier, J.; Oppong, E.; Cato, A. C. B.; Hirtz, M.; Fuchs, H.
2012. Small, 8, 585–591. doi:10.1002/smll.201101694 -
PEST-domain-enriched tyrosine phosphatase and glucocorticoids as regulators of anaphylaxis in mice
Obiri, D. D.; Flink, N.; Maier, J. V.; Neeb, A.; Maddalo, D.; Thiele, W.; Menon, A.; Stassen, M.; Kulkarni, R. A.; Garabedian, M. J.; Barrios, A. M.; Cato, A. C. B.
2012. Allergy, 67, 175–182. doi:10.1111/j.1398-9995.2011.02731.x -
Toxic and non-toxic aggregates from the SBMA and normal forms of androgen receptor have distinct oligomeric structures
Jochum, T.; Ritz, M. E.; Schuster, C.; Funderburk, S. F.; Jehle, K.; Schmitz, K.; Brinkmann, F.; Hirtz, M.; Moss, D.; Cato, A. C. B.
2012. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1822, 1070–1078. doi:10.1016/j.bbadis.2012.02.006 -
Bag-1 proteins inhibit prostate cancer cell growth through a distinct sequence that binds the glucose regulated protein GRP78
Maddalo, D.; Neeb, A.; Jehle, K.; Schmitz, K.; Walther, T.; Shatkina, L.; Muhle-Goll, C.; Gopal, S. M.; Wenzel, W.; Ulrich, A. S.; Cato, A. C. B.
2011. 3rd Internat.Meeting on Cell Stress and Apoptosis - to Arturo, Salerno, I, June 23-25, 2011 -
Dip-pen nanolithography and TIRF microscopy as tools for the study of the localisation and dynamic behaviour of the GR at the plasma membrane of mast cells
Oppong, E.; Hedde, N.; Sekula-Neuner, S.; Fuchs, H.; Nienhaus, G. U.; Cato, A. C. B.
2011. Nuclear Receptors : From Molecular Mechanism to Health and Disease, EMBO Meeting, Sitges, E, September 16-20, 2011 -
Steroid hormones regulation of metastasis-associated chaperone proteins agr2 and agr3 in prostate cancer cells
Bu, H.; Schweiger, M.; Fuchsberger, C.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Manke, T.; Cato, A. C. B.; Klocker, H.
2011. 26th Annual Congress of the European Association of Urology, Wien, A, March 18-22, 2011 European Urology Supplements, 10(2011) (Abstract) -
Steroid hormones regulation of metastasis-associated chaperone proteins agr2 and agr3 in prostate cancer cells
Bu, H.; Schweiger, M.; Fuchsberger, C.; Wunderlich, A.; Timmermann, B.; Kerick, M.; Manke, T.; Cato, A. C. B.; Klocker, H.
2011. European urology / Supplements, 26th Annual Congress of the European Association of Urology, Wien, A, March 18-22, 2011, (Abstract), 10, 264–265 -
Pro-apoptotic properties of Bag-1 peptides in the control of prostate cancer cell growth
Maddalo, D.; Neeb, A.; Jehle, K.; Schmitz, K.; Shatkina, L.; Muhle-Goll, C.; Gopal, S. M.; Wenzel, W.; Ulrich, A. S.; Cato, A. C. B.
2011. 102nd Annual Meeting of the American Association for Cancer Research (AACR), Orlando, Fla., April 2-6, 2011 Cancer Research, 71(2011) Nr.8, Suppl.1 Abstract 5403 -
The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection
Bu, H.; Bormann, S.; Schäfer, G.; Horninger, W.; Massoner, P.; Neeb, A.; Lakshmanan, V. K.; Maddalo, D.; Nestl, A.; Sültmann, H.; Cato, A. C. B.; Klocker, H.
2011. The Prostate, 71, 575–587. doi:10.1002/pros.21273 -
Depletion of the cellular levels of Bag-1 proteins attenuates phorbol ester-induced downregulation of IκBα and nuclear accumulation of NF-κB
Maier, J. V.; Volz, Y.; Berger, C.; Schneider, S.; Cato, A. C. B.
2010. Biochemical and Biophysical Research Communications, 401, 406–11. doi:10.1016/j.bbrc.2010.09.067 -
Cross-talk between the p38α and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation
Staples, C. J.; Owens, D. M.; Maier, J. V.; Cato, A. C. B.; Keyse, S. M.
2010. Journal of Biological Chemistry, 285, 25928–25940. doi:10.1074/jbc.M110.117911 -
Mast cell activation on allergen arrays prepared by lipid dip-pen nanolithography
Sekula-Neuner, S.; Maier, J.; Obiri, D.; Cato, A. C. B.; Fuchs, H.
2010. Bioactive Lipids: Biochemistry and Diseases, Keystone Symp.on Molecular and Cellular Biology, Kyoto, J, June 6-11, 2010 -
Specific N-terminal mutations in the human androgen receptor induce cytotoxicity
Funderburk, S. F.; Shatkina, L.; Mink, S.; Weis, Q.; Weg-Remers, S.; Cato, A. C. B.
2009. Neurobiology of Aging, 30, 1851–64. doi:10.1016/j.neurobiolaging.2007.12.023 -
Increased inflammation, impaired bacterial clearance, and metabolic disruption after Gram-negative sepsis in Mkp-1-deficient mice
Frazier, J.; Wang, X.; Wancket, L. M.; Li, X. A.; Meng, X.; Nelin, L. D.; Cato, A. C. B.; Liu, Y.
2009. Journal of Immunology, 183, 7411–19. doi:10.4049/jimmunol.0804343 -
Protein templating and cell culture on lipid nanoarrays
Sekula-Neuner, S.; Fuchs, J.; Weg-Remers, S.; Ellmark, P.; Borrebaeck, C. A. K.; Siebenbrock, J.; Seibold, P.; Schunck, T.; Fischer, R.; Maier, J.; Cato, A. C.; Engin, S.; Wedlich, D.; Welle, A.; Fuchs, H.; Lenhert, S.
2009. CFN Summer School on Nano-Biology, Bad Herrenalb, September 8-11, 2009 -
Regulation of hAG-2 and hAG-3 transcripts inprostate cancer
Bu, H.; Seifarth, C.; Schäfer, G.; Cato, A. C. B.; Klocker, H.
2008. 32nd FEBS Congress, Wien, A, July 7-12,2007 FEBS Journal, 274(2007) Suppl.1, (Abstract) -
The glucocorticoid receptor controls hepatic dyslipidemia through Hes1
Lemke, U.; Krones-Herzig, A.; Diaz, M. B.; Narvekar, P.; Ziegler, A.; Vegiopoulos, A.; Cato, A. C. B.; Bohl, S.; Klingmüller, U.; Screaton, R. A.; Müller-Decker, K.; Kersten, S.; Herzig, S.
2008. Cell Metabolism, 8, 212–23. doi:10.1016/j.cmet.2008.08.001 -
Regulation of hAG-2 and hAG-3 transcripts inprostate cancer
Bu, H.; Seifarth, C.; Schäfer, G.; Cato, A. C. B.; Klocker, H.
2007. The FEBS journal, 274, 173. doi:10.1111/j.0014-2956.2007.05861_3.x -
Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation
Horsch, K.; Wet, H. de; Schuurmans, M. M.; Allie-Reid, F.; Cato, A. C. B.; Cunningham, J.; Burrin, J. M.; Hough, F. S.; Hulley, P. A.
2007. Molecular Endocrinology, 21, 2929–40. doi:10.1210/me.2007-0153 -
Dual specificity phosphatase 1 knockout mice show enhanced susceptibility to anaphylaxis but are sensitive to glucocorticoids
Maier, J. V.; Brema, S.; Tuckermann, J.; Herzer, U.; Klein, M.; Stassen, M.; Moorthy, A.; Cato, A. C. B.
2007. Molecular Endocrinology, 21, 2663–71. doi:10.1210/me.2007-0067 -
Overexpression and gene amplification of BAG-IL in hormone-refractory prostate cancer
Mäki, H. E.; Saramäki, O. R.; Shatkina, L.; Martikainen, P. M.; Tammela, T. L. J.; Weerden, W. M. van; Vessella, R. L.; Cato, A. C. B.; Visakorpi, T.
2007. Journal of Pathology, 212, 395–401. doi:10.1002/path.2186 -
Nuclear hormome receptors: regulators of gene transcription and cellular signalling
Cato, A. C. B.; Shatkina, L.
2007. Ganten, D. [Hrsg.] Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine Berlin [u.a.] : Springer, 2006, 1314–20 -
Light-inducible and clock-controlled expression of MAP kinase phosphatase 1 in mouse central pacemaker neurons
Doi, M.; Cho, S.; Yujnovsky, I.; Hirayama, J.; Cermakian, N.; Cato, A. C. B.; Sassone-Corsi, P.
2007. Journal of Biological Rhythms, 22, 127–39. doi:10.1177/0748730406298332 -
Androgen receptor, polyglutamine stretch amplification and motor neuropathy
Cato, A. C. B.
2007. Androgens 2006, Cambridge, GB, September 25-27, 2007 -
SBMA pathology and phosphorylation of the androgen receptor
Funderburk, S.; Shatkina, L.; Mink, S.; Weis, Q.; Cato, A. C. B.
2007. Neurodegenerative Diseases : Molecular Mechanisms in a Functional Genomics Framework, Berlin, September 6-9, 2006 -
Glucocorticoid receptor: an integrator of multiple signal transduction pathways and diverse physiological processes
Cato, A. C. B.
2007. Omics Informatics Symp., Tokyo, J, March 20-21, 2006 -
Ultra-sensitive detection of proteins by a bio-barcode nanoparticle approach using a micro-magnetic reactor
Schneider, S.; Eberhardt, P.; Herzer, U.; Theilacker, N.; Berensmeier, S.; Rogge, T.; Weiß, C.; Cato, A. C. B.
2006. 2nd FRONTIERS Annual Meeting, Acireale, I, October 24-26, 2006 -
Aplidin induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation
Gonzalez-Santiago, L.; Suarez, Y.; Zarich, N.; Munoz-Alonso, M. J.; Cuadrado, A.; Tormo, T.; Maier, J. V.; Moorthy, A.; Cato, A. C. B.; Rojas, J. M.; Munoz, A.
2006. Cell Death and Differentiation, 13, 1968–81. doi:10.1038/sj.cdd.4401898 -
Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index
Schäcke, H.; Rehwinkel, H.; Asadullah, K.; Cato, A. C. B.
2006. Experimental Dermatology, 15, 565–73. doi:10.1111/j.1600-0625.2006.00453.x -
Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer
Zhang, C. W.; Kolb, A.; Büchler, P.; Cato, A. C. B.; Mattern, J.; Rittgen, W.; Edler, L.; Debatin, K. M.; Büchler, M. W.; Friess, H.; Herr, I.
2006. BMC Cancer, 6, 61. doi:10.1186/1471-2407-6-61 -
Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock
Hammer, M.; Mages, J.; Dietrich, H.; Servatius, A.; Howells, N.; Cato, A. C. B.; Lang, R.
2006. Journal of Experimental Medicine, 203, 15–20. doi:10.1084/jem.20051753 -
Androgen receptor
Cato, A. C. B.
2005. European Congress of Endocrinology, Göteborg, S, September 3-7, 2005 -
SBMA pathology and phosphorylation of the androgen receptor
Funderburk, S.; Shatkina, L.; Weis, Q.; Huber, A.; Cato, A. C. B.
2005. 2nd Meeting on Molecular Mechanisms of Neurodegeneration, Milano, I, May 7-10, 2005 -
Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens
Whitaker, H. C.; Hanrahan, S.; Totty, N.; Gamble, S. C.; Waxman, J.; Cato, A. C. B.; Hurst, H. C.; Bevan, C. L.
2004. Clinical Cancer Research, 10, 7392–7401 -
The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy
Cato, A. C. B.; Schäcke, H.; Sterry, W.; Asadullah, K.
2004. Current Drug Targets - Inflammation & Allergy, 3, 345–51 -
Molecular chaperones and cochaperones as regulators of the nuclear action of steroid receptors
Cato, A. C. B.
2004. Graduate College 340 - Methods to Determine the Structure of Proteins and Cellular Components, Hirschegg, A, September 11-18, 2004 -
Polyglutamine stretch amplification in androgen receptor and neurotoxicity: lessons from Drosophila melanogaster
Cato, A. C. B.
2004. Symp.on Androgen Receptor Function (Androgen 2004), Berlin, October 7-8, 2004 -
Glucocorticoids synergize with IL-1ß to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells
Sakai, A.; Han, J. H.; Cato, A. C. B.; Akira, S.; Li, J. D.
2004. BMC Molecular Biology, 2, 5. doi:10.1186/1471-2199-5-2 -
The androgen receptor: molecular biology
Klocker, H.; Gromoll, J.; Cato, A. C. B.
2004. Nieschlag, E. [Hrsg.] Testosterone : Action, Deficiency, Substitution Cambridge : Cambridge Univ.Press, 2004 -
Androgen receptor cross-talk and implications for intersex phenotype
Cato, A. C. B.
2004. Intersex - from Gene to Gender, Lübeck, April 1-3, 2004 -
The cochaperone Bag-1 as a ligand activated repressor of glucocorticoid receptor action
Hong, W.; Herzer, U.; Martin, E.; Cato, A. C. B.
2004. 16th Internat.Symp.of the Journal of Steroid Biochemistry and Molecular Biology, Seefeld, A, June 5-8, 2004 -
Non-classical signaling and cross-talk of androgen receptor
Cato, A. C. B.
2004. 6th European Federation of Endocrine Societies Postgraduate Course in Molecular and Cellular Endocrinology, Berlin, June 27-29, 2003 7th European Federation of Endocrine Societies Postgraduate Course in Molecular and Cellular Endocrinology, Berlin, October 3-5, 2004 -
Membrane localization and rapid non-transcriptional action of the androgen receptor
Mink, S.; Shatkina, L.; Nestl, A.; Cato, A. C. B.
2004. Watson, C.S. [Hrsg.] The Identities of Membrane Steroid Receptors :. and Other Proteins Mediating Nongenomic Steroid Action Dordrecht : Kluwer Acad.Publ., 2003, 111–17 -
The Cochaperone Bag-1L enhances androgen receptor action via interaction with the NH₂-terminal region of the receptor
Shatkina, L.; Mink, S.; Rogatsch, H.; Klocker, H.; Langer, G.; Nestl, A.; Cato, A. C. B.
2003. Molecular and Cellular Biology, 23, 7189–97. doi:10.1128/MCB.23.20.7189-7197.2003 -
Rapid signaling and cross-talk by androgen receptor
Cato, A. C. B.
2003. 3rd Internat.Meeting on Rapid Responses to Steroid Hormones, Firenze, I, September 12-14, 2003 -
Attenuation of IgE-receptor signalling in mast cells as a molecular basis for the antiallergic action of glucocorticoids
Sancono, A.; Kassel, O.; Maier, J.; Hesslinger, C.; Cato, A. C. B.
2003. 1st ERS Lung Science Conf., Taormina, I, March 28-30, 2003 FEBS Young Scientist Forum, Bruxelles, B, July 1-3, 2003 European Respiratory Journal, 22(2003) Suppl., S-41S -
Attenuation of IgE-receptor signalling in mast cells as a molecular basis for the antiallergic action of glucocorticoids
Sancono, A.; Kassel, O.; Maier, J.; Hesslinger, C.; Cato, A. C. B.
2003. European Respiratory Journal, 1st ERS Lung Science Conf., Taormina, I, March 28-30, 2003 FEBS Young Scientist Forum, Bruxelles, B, July 1-3, 2003, Suppl., S-41S, 22, 40 -
Inhibition of p38 MAPK by glucocorticoid via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of Toll-like receptor 2
Imasato, A.; Desbois-Mouthon, C.; Han, J.; Kai, H.; Cato, A. C. B.; Akira, S.; Li, J. D.
2003. Journal of Biological Chemistry, (2002), 277, 47444–50 -
Mast cells as targets for glucocorticoids in the treatment of allergic disorders
Kassel, O.; Cato, A. C. B.
2002. Cato, A.C.B. [Hrsg.] Recent Advances in Glucocorticoid Receptor Action Berlin [u.a.] : Springer, 2002 (Ernst Schering Research Foundation Workshop ; 40), 153–76 -
Regulation of androgen receptor action by a chaperone-cochaperone complex, composed of BAG-1L and HSP70
Shatkina, L.; Mink, S.; Langer, G.; Cato, A. C. B.
2002. Symp.on Androgen Receptor Function, Groot Begijnhof, Leuven, B, September 13-14, 2002 -
Functional analysis of human androgen receptor with a polyglutamine stretch amplification
Korali, Z.; Weih, D.; Zinke, I.; Abert, S.; Huber, A.; Paulsen, R.; Cato, A. C. B.
2002. 2nd European Congress of Andrology, Malmö, S, September 19-22, 2002 -
Rapid actions of steroid receptors in cellular signaling pathways
Cato, A. C. B.; Nestl, A.; Mink, S.
2002. Science, ’s STKE Signal Transduction Knowledge Environment, (2002) Issue 138, re9 -
Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase
Shuto, T.; Imasato, A.; Jono, H.; Sakai, A.; Xu, H.; Watanabe, T.; Rixter, D. D.; Kai, H.; Andalibi, A.; Linthicum, F.; Guan, Y. L.; Han, J.; Cato, A. C. B.; Lim, D. J.; Akira, S.; Li, J. D.
2002. Journal of Biological Chemistry, 277, 17263–70 -
Warum scheitert die Antihormontherapie bei fortgeschrittenem Prostatakrebs?
Cato, A. C. B.; Shatkina, L.; Nestl, A.; Mink, S.
2002. Nachrichten - Forschungszentrum Karlsruhe, 34, 41–48 -
The amino terminus of the human AR is target for corepressor action and antihormone agonism
Dotzlaw, H.; Moehren, U.; Mink, S.; Cato, A. C. B.; Iniguez Lluhi, J. A.; Baniahmad, A.
2002. Molecular Endocrinology, 16, 661–73 -
Dichotomy of glucocorticoid action in the immune system
Asadullah, K.; Schäcke, H.; Cato, A. C. B.
2002. Trends in immunology, 23 (3), 120–122. doi:10.1016/S1471-4906(01)02147-0 -
Interdigital apoptosis and downregulation of BAG-1 expression in mouse autopods
Crocoll, A.; Herzer, U.; Ghyselinck, N. B.; Chambon, P.; Cato, A. C. B.
2002. Mechanisms of development, 111 (1-2), 149–152. doi:10.1016/S0925-4773(01)00598-6 -
Glucocorticoids inhibit MAP-kinase via increased expression and decreased degradation of MKP-1
Kassel, O.; Sancono, A.; Krätzschmar, J.; Kreft, B.; Cato, A. C. B.
2002. Keystone Symp.’Protein Phosphorylation and Mechanisms of Cellular Regulation (X2)’, Taos, N.M., March 5-10, 2002 -
A Drosophila model for the functional analysis of human androgen receptor with a polyglutamine stretch amplification
Korali, Z.; Weih, D.; Abert, S.; Mink, S.; Huber, A.; Paulsen, R.; Zinke, I.; Pankratz, M. J.; Cato, A. C. B.
2002. Keystone Symp.’Nuclear Receptor Superfamily (D4)’, Snowbird, Utah, April 13-19, 2002 -
BAG-1 family of cochaperones in the modulation of nuclear receptor action
Cato, A. C. B.; Mink, S.
2002. Journal of Steroid Biochemistry and Molecular Biology, (2001), 78, 379–88 -
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
Kassel, O.; Sancono, A.; Krätzschmar, J.; Kreft, B.; Stassen, M.; Cato, A. C. B.
2001. The EMBO Journal, (2001), 20 (24), 7108–7116. doi:10.1093/emboj/20.24.7108 -
A Drosophila model for spinal and bulbar muscular atrophy
Korali, Z.; Weih, D.; Mink, S.; Huber, A.; Paulsen, R.; Zinke, I.; Pankratz, M. J.; Cato, A. C. B.
2001. Nuclear Receptors in Health and Disease, Mont Saint Odile, F, September 14-17, 2001 -
BAG-1 family of cochaperones in the modulation of nuclear receptor action
Crocoll, A.; Mink, S.; Hübner, S.; Schneikert, J.; Cato, A. C. B.
2001. Current Topics in Steroid Research, 3, 53–62 -
Modulation of glucocorticoid- and androgen receptor action by Bag-1 cochaperones
Mink, S.; Schneikert, J.; Hong, W.; Shatkina, L.; Cato, A. C. B.
2001. Euro Conf.and EMBO Workshop, Sant Feliu de Guixols, E, May 26-31, 2001 -
Alteration of the stability of Bag-1 protein in the control of olfactory neuronal apoptosis
Sourisseau, T.; Desbois, C.; Debure, L.; Bowtell, D. D. L.; Cato, A. C. B.; Schneikert, J.; Moyse, E.; Michel, D.
2001. Journal of Cell Science, 114, 1409–16 -
Expression level-dependent contribution of glucocorticoid receptor domains for functional interaction with STAT5
Doppler, W.; Windegger, M.; Soratroi, C.; Tomasi, J.; Lechner, J.; Rusconi, S.; Cato, A. C. B.; Almlöf, T.; Liden, J.; Okret, S.; Gustafson, J. A.; Richard-Foy, H.; Starr, D. B.; Klocker, H.; Edwards, D.; Geymayer, S.
2001. Molecular and Cellular Biology, 21, 3266–79 -
Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor
Schneikert, J.; Hübner, S.; Langer, G.; Petri, T.; Jäättelä, M.; Reed, J.; Cato, A. C. B.
2000. The EMBO Journal, 19, 6508–16 -
Modulation of androgen receptor action
Shatkina, L.; Mink, S.; Becker, M.; Cato, A. C. B.
2000. Symp.on Androgen Receptor Function - Androgens 2000, Rotterdam, NL, September 22-23, 2000 -
BAG-1M: a potential specificity determinant of corticosteroid receptor action
Crocoll, A.; Schneikert, J.; Hübner, S.; Martin, E.; Cato, A. C. B.
2000. Kidney International, 57, 1265–69 -
Isoform-specific expression of BAG-1 in mouse development
Crocoll, A.; Blum, M.; Cato, A. C. B.
2000. Mechanisms of Development, 91, 355–59 -
Cytoplasmic localization and the choice of ligand determine aggregate formation by androgen receptor with amplified polyglutamine stretch
Becker, M.; Martin, E.; Schneikert, J.; Krug, H. F.; Cato, A. C. B.
2000. The Journal of Cell Biology, 149, 255–62 -
How to produce androgen antagonists
Cato, A. C. B.; Mink, S.; Becker, M.; Shatkina, L.
2000. Meeting of the European Society of Human Reproduction and Embryology, Bologna, I, June 25-28, 2000 -
Rapid signalling by androgen receptor in prostate cancer cells
Peterziel, H.; Mink, S.; Schonert, A.; Becker, M.; Klocker, H.; Cato, A. C. B.
1999. Oncogene, 18, 6322–29 -
A nuclear action of the Eukaryotic cochaperone RAP46 in downregulation of glucocorticoid receptor activity
Schneikert, J.; Hübner, S.; Martin, E.; Cato, A. C. B.
1999. The Journal of Cell Biology, 146, 929–40 -
Androgen receptor signalling pathways: role of BAG-IL in androgen receptor action
Shatkina, L.; Mink, S.; Cato, A. C. B.
1999. 28.Colloquium Endocrinologicum, Heidelberg, 5.November 1999 -
Die Rolle der Kerntranslokation des Co-Chaperons RAP46 in der Regulation der transaktivierenden Wirkung des Glucocorticoidrezeptors
Hübner, S.; Schneickert, J.; Martin, E.; Cato, A. C. B.
1999. 28.Colloquium Endocrinologicum, Heidelberg, 5.November 1999 -
Steroid hormone receptors and their coactivators and corepressors
Cato, A. C. B.
1999. 3rd Postgraduate Course in Molecular and Cellular Endocrinology, European Federation of Endocrine Societies, Münster, July 7-11, 1999 -
Mechanism of androgen receptor activation and possible implications for chemoprevention trials
Klocker, H.; Culig, Z.; Eder, I. E.; Nessler-Menardi, C.; Hobisch, A.; Putz, T.; Bartsch, G.; Peterziel, H.; Cato, A. C. B.
1999. European Urology, 35, 413–19 -
Androgen receptor action: two receptors-two ligands theory revisited
Cato, A. C. B.
1999. Round Table Discussion on PR and AR Isoforms, Schering AG, Berlin, July 5, 1999 -
Eukaryotic cochaperone RAP46/BAG-1M as potential specificity determinant in corticosteroid receptor action
Schneikert, J.; Hübner, S.; Crocoll, A.; Martin, E.; Cato, A. C. B.
1999. Forefront Meeting of the Internat.Soc.of Nephrology ’News in Aldosterone Action’, Paris, F, August 15-18, 1999 -
The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription
Ortiz, L.; Aza-Blanc, P.; Zannini, M.; Cato, A. C. B.; Santisteban, P.
1999. The Journal of Biological Chemistry, 274, 15213–21 -
Expression, structure, and function of androgen receptor in advanced prostatic carcinoma
Culig, Z.; Hobisch, A.; Hittmair, A.; Peterziel, H.; Cato, A. C. B.; Bartsch, G.; Klocker, H.
1999. The Prostate, (1998), 35, 63–70 -
Regulation of E-cadherin gene expression during tumor progression: the role of a new Ets-binding site and the E-pal element
Rodrigo, I.; Cato, A. C. B.; Cano, A.
1999. Experimental Cell Research, 248, 358–71 -
Androgen receptor signaling in prostate cancer cells
Cato, A. C. B.; Krug, H. F.; Peterziel, H.
1999. 23.Jahrestagung der Deutschen Gesellschaft für Zellbiologie, Rostock, 14.-18.März 1999