Publications 2021


  1. CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues.
    Yu, X.; Munoz-Sagredo, L.; Streule, K.; Muschong, P.; Bayer, E.; Walter, R. J.; Gutjahr, J. C.; Greil, R.; Concha, M. L.; Müller-Tidow, C.; Hartmann, T. N.; Orian-Rousseau, V.
    2021. Blood, 138 (12), 1067–1080. doi:10.1182/blood.2020006343
  2. Molecular Design and Synthesis of Dicarbazolophane-Based Centrosymmetric Through-Space Donors for Solution-Processed Thermally Activated Delayed Fluorescence OLEDs.
    Zhang, Z.; Diesing, S.; Crovini, E.; Gupta, A. K.; Spuling, E.; Gan, X.; Fuhr, O.; Nieger, M.; Hassan, Z.; Samuel, I. D. W.; Bräse, S.; Zysman-Colman, E.
    2021. Organic Letters, 23 (17), 6697–6702. doi:10.1021/acs.orglett.1c02273
  3. Synthesis and SAR evaluation of coumarin derivatives as potent cannabinoid receptor agonists.
    Mohr, F.; Hurrle, T.; Burggraaff, L.; Langer, L.; Bemelmans, M. P.; Knab, M.; Nieger, M.; van Westen, G. J. P.; Heitman, L. H.; Bräse, S.
    2021. European Journal of Medicinal Chemistry, 220, Art. Nr. 113354. doi:10.1016/j.ejmech.2021.113354
  4. Synthesis and post-polymerization modification of poly(propargyl 2-ylidene-acetate).
    Li, Z.; Mutlu, H.; Theato, P.; Bräse, S.
    2021. European polymer journal, 156, Art.-Nr.: 110564. doi:10.1016/j.eurpolymj.2021.110564
  5. Substituted pyrazoles and their heteroannulated analogs—recent syntheses and biological activities.
    Ramadan, M.; Aly, A. A.; El‐haleem, L. E. A.; Alshammari, M. B.; Bräse, S.
    2021. Molecules, 26 (16), Art.-Nr.: 4995. doi:10.3390/molecules26164995Full textFull text of the publication as PDF document
  6. Cyclic Peptoid-Peptide Hybrids as Versatile Molecular Transporters.
    Herlan, C. N.; Meschkov, A.; Schepers, U.; Bräse, S.
    2021. Frontiers in Chemistry, 9, Art. Nr.: 696957. doi:10.3389/fchem.2021.696957Full textFull text of the publication as PDF document
  7. Multigram‐Scale Kinetic Resolution of 4‐Acetyl[2.2]Paracyclophane Ru‐Catalyzed Enantioselective Hydrogenation: Accessing [2.2]Paracyclophanes with Planar and Central Chirality.
    Zippel, C.; Hassan, Z.; Parsa, A. Q.; Hohmann, J.; Bräse, S.
    2021. Advanced synthesis & catalysis, 363 (11), 2861–2865. doi:10.1002/adsc.202001536Full textFull text of the publication as PDF document
  8. Investigation of Luminescent Triplet States in Tetranuclear Cu Complexes: Thermochromism and Structural Characterization.
    Boden, P.; Di Martino-Fumo, P.; Busch, J. M.; Rehak, F. R.; Steiger, S.; Fuhr, O.; Nieger, M.; Volz, D.; Klopper, W.; Bräse, S.; Gerhards, M.
    2021. Chemistry - a European journal, 27 (17), 5439–5452. doi:10.1002/chem.202004539Full textFull text of the publication as PDF document
  9. Halogen-bonded one-dimensional chains of functionalized ditopic bipyridines co-crystallized with mono-, di-, and triiodofluorobenzenes.
    Vulpe, E.; Grosjean, S.; Hassan, Z.; Bulach, V.; Hosseini, M. W.; Bräse, S.
    2021. CrystEngComm, 23 (24), 4247–4251. doi:10.1039/d1ce00494hFull textFull text of the publication as PDF document
  10. Fabrication of Quasi‐2D Shape‐Tailored Microparticles using Wettability Contrast‐Based Platforms.
    Neto, M. D.; Stoppa, A.; Neto, M. A.; Oliveira, F. J.; Gomes, M. C.; Boccaccini, A. R.; Levkin, P. A.; Oliveira, M. B.; Mano, J. F.
    2021. Advanced materials, 33 (14), Art.-Nr.: 2007695. doi:10.1002/adma.202007695
  11. Formal Semisynthesis of Demethylgorgosterol Utilizing a Stereoselective Intermolecular Cyclopropanation Reaction.
    Rosenbaum, N.; Schmidt, L.; Mohr, F.; Fuhr, O.; Nieger, M.; Bräse, S.
    2021. European journal of organic chemistry, 2021 (10), 1568–1574. doi:10.1002/ejoc.202100035Full textFull text of the publication as PDF document
  12. A Brief History of OLEDs—Emitter Development and Industry Milestones.
    Hong, G.; Gan, X.; Leonhardt, C.; Zhang, Z.; Seibert, J.; Busch, J. M.; Bräse, S.
    2021. Advanced materials, 33 (9), Art.-Nr.: 2005630. doi:10.1002/adma.202005630Full textFull text of the publication as PDF document
  13. Effects of a Novel GPR55 Antagonist on the Arachidonic Acid Cascade in LPS-Activated Primary Microglial Cells.
    Saliba, S. W.; Gläser, F.; Deckers, A.; Keil, A.; Hurrle, T.; Apweiler, M.; Ferver, F.; Volz, N.; Endres, D.; Bräse, S.; Fiebich, B. L.
    2021. International journal of molecular sciences, 22 (5), Art.-Nr. 2503. doi:10.3390/ijms22052503Full textFull text of the publication as PDF document
  14. Fast Nanoliter-Scale Cell Assays Using Droplet Microarray–Mass Spectrometry Imaging.
    RamalloGuevara, C.; Paulssen, D.; Popova, A. A.; Hopf, C.; Levkin, P. A.
    2021. Advanced Biology, 5 (3), Art.-Nr.: 2000279. doi:10.1002/adbi.202000279Full textFull text of the publication as PDF document
  15. Various Structural Design Modifications : para-Substituted Diphenylphosphinopyridine Bridged Cu(I) Complexes in Organic Light-Emitting Diodes.
    Busch, J. M.; Koshelev, D. S.; Vashchenko, A. A.; Fuhr, O.; Nieger, M.; Utochnikova, V. V.; Bräse, S.
    2021. Inorganic chemistry, 60 (4), 2315–2332. doi:10.1021/acs.inorgchem.0c03187
  16. ChemSpectra: a web-based spectra editor for analytical data.
    Huang, Y.-C.; Tremouilhac, P.; Nguyen, A.; Jung, N.; Bräse, S.
    2021. Journal of Cheminformatics, 13 (1), Art.-Nr. 8. doi:10.1186/s13321-020-00481-0Full textFull text of the publication as PDF document
  17. A Synthetic Strategy for Cofacial Porphyrin-Based Homo- and Heterobimetallic Complexes.
    Schissler, C.; Schneider, E. K.; Felker, B.; Weis, P.; Nieger, M.; Kappes, M. M.; Bräse, S.
    2021. Chemistry - a European journal, 27 (9), 3047–3054. doi:10.1002/chem.202002394Full textFull text of the publication as PDF document
  18. Id1 and Id3 Are Regulated Through Matrix‐Assisted Autocrine BMP Signaling and Represent Therapeutic Targets in Melanoma.
    Sedlmeier, G.; Al‐Rawi, V.; Buchert, J.; Yserentant, K.; Rothley, M.; Steshina, A.; Gräßle, S.; Wu, R.; Hurrle, T.; Richer, W.; Decraene, C.; Thiele, W.; Utikal, J.; Abuillan, W.; Tanaka, M.; Herten, D.; Hill, C. S.; Garvalov, B. K.; Jung, N.; Bräse, S.; Sleeman, J. P.
    2021. Advanced therapeutics, 4 (2), Art.-Nr.: 2000065. doi:10.1002/adtp.202000065Full textFull text of the publication as PDF document
  19. Regioselective and stereoselective synthesis of epithiomethanoiminoindeno[1,2-b]furan-3-carbonitrile: heterocyclic [3.3.3]propellanes.
    Hassan, A. A.; Mohamed, N. K.; Aly, A. A.; Tawfeek, H. N.; Bräse, S.; Nieger, M.
    2021. Molecular diversity, 25 (1), 99–108. doi:10.1007/s11030-019-10027-8
  20. Rigid Multidimensional Alkoxyamines: A Versatile Building Block Library.
    Matt, Y.; Wessely, I.; Gramespacher, L.; Tsotsalas, M.; Bräse, S.
    2021. European journal of organic chemistry, 2021 (2), 239–245. doi:10.1002/ejoc.202001415Full textFull text of the publication as PDF document
  21. Assembly of Multi‐Spheroid Cellular Architectures by Programmable Droplet Merging.
    Cui, H.; Wang, X.; Wesslowski, J.; Tronser, T.; Rosenbauer, J.; Schug, A.; Davidson, G.; Popova, A. A.; Levkin, P. A.
    2021. Advanced materials, 33 (4), Art.-Nr.: 2006434. doi:10.1002/adma.202006434Full textFull text of the publication as PDF document
  22. Regioselective ortho-Palladation of [2.2]Paracyclophane Scaffolds: Accessing Planar and Central Chiral N,C-Palladacycles.
    Zippel, C.; Bartholomeyzik, T.; Friedmann, C.; Nieger, M.; Hassan, Z.; Bräse, S.
    2021. European Journal of Organic Chemistry, 2021 (36), 5090–5093. doi:10.1002/ejoc.202101066Full textFull text of the publication as PDF document
  23. Substrate-Independent and Re-Writable Surface Patterning by Combining Polydopamine Coatings, Silanization, and Thiol-Ene Reaction.
    Li, S.; Scheiger, J. M.; Wang, Z.; Dong, Z.; Welle, A.; Trouillet, V.; Levkin, P. A.
    2021. Advanced Functional Materials. doi:10.1002/adfm.202107716Full textFull text of the publication as PDF document
  24. Inherently UV Photodegradable Poly(methacrylate) Gels.
    Scheiger, J. M.; Li, S.; Brehm, M.; Bartschat, A.; Theato, P.; Levkin, P. A.
    2021. Advanced Functional Materials, Art.-Nr.: 2105681. doi:10.1002/adfm.202105681Full textFull text of the publication as PDF document
  25. Dynamic porous organic polymers with tuneable crosslinking degree and porosity.
    Wessely, I. D.; Matt, Y.; An, Q.; Bräse, S.; Tsotsalas, M.
    2021. RSC Advances, 11 (44), 27714–27719. doi:10.1039/d1ra05265aFull textFull text of the publication as PDF document
  26. Novel Cofacial Porphyrin-Based Homo- and Heterotrimetallic Complexes of Transition Metals.
    Schissler, C.; Schneider, E. K.; Lebedkin, S.; Weis, P.; Niedner-Schatteburg, G.; Kappes, M. M.; Bräse, S.
    2021. Chemistry - A European Journal. doi:10.1002/chem.202102376Full textFull text of the publication as PDF document
  27. Macrocyclic tetramers—structural investigation of peptide-peptoid hybrids.
    Herlan, C. N.; Sonnefeld, A.; Gloge, T.; Brückel, J.; Schlee, L. C.; Muhle-Goll, C.; Nieger, M.; Bräse, S.
    2021. Molecules, 26 (15), 4548. doi:10.3390/molecules26154548
  28. Skeletal Editing—Nitrogen Deletion of Secondary Amines by Anomeric Amide Reagents.
    Zippel, C.; Seibert, J.; Bräse, S.
    2021. Angewandte Chemie / International edition, 60 (36), 19522–19524. doi:10.1002/anie.202107490Full textFull text of the publication as PDF document
  29. Avoiding the Center-Symmetry Trap: Programmed Assembly of Dipolar Precursors into Porous, Crystalline Molecular Thin Films.
    Nefedov, A.; Haldar, R.; Xu, Z.; Kühner, H.; Hofmann, D.; Goll, D.; Sapotta, B.; Hecht, S.; Krstić, M.; Rockstuhl, C.; Wenzel, W.; Bräse, S.; Tegeder, P.; Zojer, E.; Wöll, C.
    2021. Advanced Materials, Art.-Nr. 2103287. doi:10.1002/adma.202103287Full textFull text of the publication as PDF document
  30. Platinum Cyclooctadiene Complexes with Activity against Gram-positive Bacteria.
    Frei, A.; Ramu, S.; Lowe, G. J.; Dinh, H.; Semenec, L.; Elliott, A. G.; Zuegg, J.; Deckers, A.; Jung, N.; Bräse, S.; Cain, A. K.; Blaskovich, M. A. T.
    2021. ChemMedChem. doi:10.1002/cmdc.202100157
  31. Corrigendum: What Controls the Orientation of TADF Emitters?.
    Naqvi, B. A.; Schmid, M.; Crovini, E.; Sahay, P.; Naujoks, T.; Rodella, F.; Zhang, Z.; Strohriegl, P.; Bräse, S.; Zysman-Colman, E.; Brütting, W.
    2021. Frontiers in Chemistry, 9. doi:10.3389/fchem.2021.632639Full textFull text of the publication as PDF document
  32. Fluorescence detected circular dichroism (FDCD) for supramolecular host–guest complexes.
    Prabodh, A.; Wang, Y.; Sinn, S.; Albertini, P.; Spies, C.; Spuling, E.; Yang, L.-P.; Jiang, W.; Bräse, S.; Biedermann, F.
    2021. Chemical science, 12 (27), 9420–9431. doi:10.1039/d1sc01411kFull textFull text of the publication as PDF document
  33. In situ sensors for flow reactors – a review.
    Li, J.; Šimek, H.; Ilioae, D.; Jung, N.; Bräse, S.; Zappe, H.; Dittmeyer, R.; Ladewig, B. P.
    2021. Reaction chemistry & engineering. doi:10.1039/d1re00038aFull textFull text of the publication as PDF document
  34. Covalent triazine frameworks based on the first pseudo-octahedral hexanitrile monomer via nitrile trimerization: Synthesis, porosity, and co2 gas sorption properties.
    Wessely, I. D.; Schade, A. M.; Dey, S.; Bhunia, A.; Nuhnen, A.; Janiak, C.; Bräse, S.
    2021. Materials, 14 (12), 3214. doi:10.3390/ma14123214Full textFull text of the publication as PDF document
  35. Quinolones as prospective drugs: Their syntheses and biological applications.
    Aly, A. A.; Ramadan, M.; Abuo-Rahma, G. E.-D. A.; Elshaier, Y. A. M. M.; Elbastawesy, M. A. I.; Brown, A. B.; Bräse, S.
    2021. Advances in Heterocyclic Chemistry. Vol. 135. Ed.: Eric F. V. Scriven, 147–196, Elsevier. doi:10.1016/bs.aihch.2020.08.001
  36. Designing Inherently Photodegradable Cell‐Adhesive Hydrogels for 3D Cell Culture.
    Rosenfeld, A.; Göckler, T.; Kuzina, M.; Reischl, M.; Schepers, U.; Levkin, P. A.
    2021. Advanced healthcare materials, 2100632. doi:10.1002/adhm.202100632Full textFull text of the publication as PDF document
  37. Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments.
    Kozielewicz, P.; Shekhani, R.; Moser, S.; Bowin, C.-F.; Wesslowski, J.; Davidson, G.; Schulte, G.
    2021. ACS Pharmacology and Translational Science, 4 (3), 1235–1245. doi:10.1021/acsptsci.1c00084Full textFull text of the publication as PDF document
  38. Facile Approach to Conductive Polymer Microelectrodes for Flexible Electronics.
    Wang, Z.; Cui, H.; Li, S.; Feng, X.; Aghassi-Hagmann, J.; Azizian, S.; Levkin, P. A.
    2021. ACS Applied Materials and Interfaces, 13 (18), 21661–21668. doi:10.1021/acsami.0c22519
  39. The Diels-Alder Approach towards Cannabinoid Derivatives and Formal Synthesis of Tetrahydrocannabinol (THC).
    Hurrle, T.; Gläser, F.; Bröhmer, M. C.; Nieger, M.; Bräse, S.
    2021. ChemistryOpen, 10 (5), 587–592. doi:10.1002/open.202000343Full textFull text of the publication as PDF document
  40. Droplet microarrays for cell culture: effect of surface properties and nanoliter culture volume on global transcriptomic landscape.
    Chakraborty, S.; Gourain, V.; Benz, M.; Scheiger, J. M.; Levkin, P. A.; Popova, A. A.
    2021. Materials Today Bio, 11, Art.-Nr.: 100112. doi:10.1016/j.mtbio.2021.100112Full textFull text of the publication as PDF document
  41. Liquid Wells as Self-Healing, Functional Analogues to Solid Vessels.
    Scheiger, J. M.; Kuzina, M. A.; Eigenbrod, M.; Wu, Y.; Wang, F.; Heißler, S.; Hardt, S.; Nestler, B.; Levkin, P. A.
    2021. Advanced Materials, 33 (23), Art.-Nr.: 2100117. doi:10.1002/adma.202100117Full textFull text of the publication as PDF document
  42. High-throughput screening of multifunctional nanocoatings based on combinations of polyphenols and catecholamines.
    Behboodi-Sadabad, F.; Li, S.; Lei, W.; Liu, Y.; Sommer, T.; Friederich, P.; Sobek, C.; Messersmith, P. B.; Levkin, P. A.
    2021. Materials Today Bio, 10, Art.-Nr.: 100108. doi:10.1016/j.mtbio.2021.100108Full textFull text of the publication as PDF document
  43. Highly NIR-emitting ytterbium complexes containing 2-(tosylaminobenzylidene)-N-benzoylhydrazone anions: structure in solution and use for bioimaging.
    Kovalenko, A. D.; Pavlov, A. A.; Ustinovich, I. D.; Kalyakina, A. S.; Goloveshkin, A. S.; Marciniak, Ł.; Lepnev, L. S.; Burlov, A. S.; Schepers, U.; Bräse, S.; Utochnikova, V. V.
    2021. Dalton Transactions, 50 (11), 3786–3791. doi:10.1039/d0dt03913f
  44. A Guide to the Composition and Functions of the Extracellular Matrix.
    Karamanos, N. K.; Theocharis, A. D.; Piperigkou, Z.; Manou, D.; Passi, A.; Skandalis, S. S.; Vynios, D. H.; Orian-Rousseau, V.; Ricard‐Blum, S.; Schmelzer, C. E. H.; Duca, L.; Durbee, M.; Afratis, N. A.; Troeberg, L.; Franchi, M.; Masola, V.; Onisto, M.
    2021. The FEBS journal, febs.15776. doi:10.1111/febs.15776
  45. Plasticity in Colorectal Cancer: Why Cancer Cells Differentiate.
    Walter, R. J.; Sonnentag, S. J.; Orian-Rousseau, V.; Munoz-Sagredo, L.
    2021. Cancers, 13 (4), 918. doi:10.3390/cancers13040918Full textFull text of the publication as PDF document
  46. Expanded Cyclotetrabenzoins.
    Eisterhold, A. M.; Puangsamlee, T.; Otterbach, S.; Bräse, S.; Weis, P.; Wang, X.; Kutonova, K. V.; Miljanić, O. Š.
    2021. Organic letters, 23 (3), 781–785. doi:10.1021/acs.orglett.0c04014
  47. Design and synthesis of hydrazinecarbothioamide sulfones as potential antihyperglycemic agents.
    Aly, A. A.; Hassan, A. A.; Makhlouf, M. M.; Alshammari, M. B.; Mohamed Naguib Abdel Hafez, S.; Refaie, M. M. M.; Bräse, S.; Nieger, M.; Ramadan, M.
    2021. Archiv der Pharmazie. doi:10.1002/ardp.202000336
  48. Transcriptome analysis of two structurally related flavonoids; Apigenin and Chrysin revealed hypocholesterolemic and ketogenic effects in mouse embryonic fibroblasts.
    Puthanveetil, P.; Kong, X.; Bräse, S.; Voros, G.; Peer, W. A.
    2021. European journal of pharmacology, 893, Art.-Nr.: 173804. doi:10.1016/j.ejphar.2020.173804
  49. Synthesis of 3,3′-methylenebis(4-hydroxyquinolin-2(1H)-ones) of prospective anti-COVID-19 drugs.
    Aly, A. A.; Hassan, A. A.; Mohamed, A. H.; Osman, E. M.; Bräse, S.; Nieger, M.; Ibrahim, M. A. A.; Mostafa, S. M.
    2021. Molecular diversity, 25, 461–471. doi:10.1007/s11030-020-10140-z