Institute of Biological and Chemical Systems - Functional Molecular Systems

Publications 2015


  1. CD44 regulates Wnt signaling at the level of LRP6.
    Orian-Rousseau, V.; Schmitt, M.
    2015. Molecular & cellular oncology, 2 (3), e995046. doi:10.4161/23723556.2014.995046Full textFull text of the publication as PDF document
  2. Hydrazoic acid and azides.
    Bräse, S.; Mende, M.; Jobelius, H. H.; Scharf, H.-D.
    2015. Ullmann’s Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim. doi:10.1002/14356007.a13_193.pub2
  3. Combinatorial synthesis and high throughput screening of lipidoids for gene delivery.
    Wu, Y.; Li, L.; Levkin, P. A.; Davidson, G.
    2015. Journal of controlled release, 213, E134-E134. doi:10.1016/j.jconrel.2015.05.226
  4. Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers.
    Kudryavtsev, K.; Ivantcova, P. M.; Muhle-Goll, C.; Churakov, A. V.; Sokolov, M. N.; Dyuba, A. V.; Arutyunyan, A. M.; Howard, J. A. K.; Yu, C.-C.; Guh, J.-H.; Zefirov, N. S.; Bräse, S.
    2015. Organic Letters, 17 (24), 6178–6181. doi:10.1021/acs.orglett.5b03154
  5. Expression screening using a Medaka cDNA library identifies evolutionarily conserved regulators of the p53/Mdm2 pathway.
    Zhang, P.; Kratz, A. S.; Salama, M.; Elabd, S.; Heinrich, T.; Wittbrodt, J.; Blattner, C.; Davidson, G.
    2015. BMC Biotechnology, 15 (1), 92. doi:10.1186/s12896-015-0208-yFull textFull text of the publication as PDF document
  6. Synthesis and post-synthetic modification of amine-, alkyne-, azide- and nitro-functionalized metal-organic frameworks based on DUT-5.
    Gotthardt, M. A.; Grosjean, S.; Brunner, T. S.; Kotzel, J.; Gänzler, A. M.; Wolf, S.; Bräse, S.; Kleist, W.
    2015. Dalton transactions, 44 (38), 16802–16809. doi:10.1039/c5dt02276bFull textFull text of the publication as PDF document
  7. Enantioselective adsorption in homochiral metal-organic frameworks: The pore size influence.
    Gu, Z. G.; Grosjean, S.; Bräse, S.; Wöll, C.; Heinke, L.
    2015. Chemical communications, 51 (43), 8998–9001. doi:10.1039/C5CC02706C
  8. Chemical synthesis and enzymatic, stereoselective hydrolysis of a functionalized dihydropyrimidine for the synthesis of β-amino acids.
    Slomka, C.; Zhong, S.; Fellinger, A.; Engel, U.; Syldatk, C.; Bräse, S.; Rudat, J.
    2015. AMB Express, 5 (1), 85. doi:10.1186/s13568-015-0174-8Full textFull text of the publication as PDF document
  9. Monolithic crystalline MOF coating: An excellent patterning and photoresist material.
    Wang, Z.; Liu, J.; Grosjean, S.; Wagner, D.; Guo, W.; Gu, Z.; Heinke, L.; Gliemann, H.; Bräse, S.; Wöll, C.
    2015. ChemNanoMat, 1, 338–345. doi:10.1002/cnma.201500031
  10. Cis-to-trans isomerization of azobenzene investigated by using thin films of metal-organic frameworks.
    Yu, X.; Wang, Z.; Buchholz, M.; Füllgrabe, N.; Grosjean, S.; Bebensee, F.; Bräse, S.; Wöll, C.; Heinke, L.
    2015. Physical chemistry, chemical physics, 17, 22721–22725. doi:10.1039/C5CP03091A
  11. Photoswitchable adsorption in metal-organic frameworks based on polar guest-host interactions.
    Wang, Z.; Grosjean, S.; Bräse, S.; Heinke, L.
    2015. ChemPhysChem, 16, 3779–3783. doi:10.1002/cphc.201500829
  12. TRIM25 has a dual function in the p53/Mdm2 circuit.
    Zhang, P.; Elabd, S.; Hammer, S.; Solozobova, V.; Yan, H.; Bartel, F.; Inoue, S.; Henrich, T.; Wittbrodt, J.; Loosli, F.; Davidson, G.; Blattner, C.
    2015. Oncogene, 34, 5729–5738. doi:10.1038/onc.2015.21
  13. Simple and expedient metal-free C-H-functionalization of fluoro-arenes by the BHAS method - Scope and limitations.
    Lindner, S.; Bräse, S.; Masters, K. S.
    2015. Journal of fluorine chemistry, 179, 102–105. doi:10.1016/j.jfluchem.2015.06.010
  14. ScreenFect A: An efficient and low toxic liposome for gene delivery to mesenchymal stem cells.
    Li, L. M.; Ruan, G. X.; HuangFu, M. Y.; Chen, Z. L.; Liu, H. N.; Li, L. X.; Hu, Y. L.; Han, M.; Davidson, G.; Levkin, P. A.; Gao, J. Q.
    2015. International journal of pharmaceutics, 488 (1-2), 1–11. doi:10.1016/j.ijpharm.2015.04.050
  15. Highly luminescent, water-soluble lanthanide fluorobenzonates : Syntheses, structures and photophysics, Part I : Lanthanide pentafluorobenzoates.
    Kalyakina, A. S.; Utochnikova, V. V.; Bushmarinov, I. S.; Ananyev, I. V.; Eremenko, I. L.; Volz, D.; Rönicke, F.; Schepers, U.; Van Deun, R.; Trigub, A. L.; Zubavichus, Y. V.; Kuzmina, N. P.; Bräse, S.
    2015. Chemistry - a European journal, 21 (49), 17921–17932. doi:10.1002/chem.201501816
  16. Synthesis of new diketopiperazines, thiolation to thiodiketopiperazines, and examination of ateir ROS-generating properties.
    Zhong, S.; Wandler, A. E. E.; Schepers, U.; Nieger, M.; Bräse, S.
    2015. European Journal of Organic Chemistry, (31), 6858–6871. doi:10.1002/ejoc.201500900
  17. Hierarchical micro-nano surface topography promotes long-term maintenance of undifferentiated mouse embryonic stem cells.
    Jaggy, M.; Zhang, P.; Greiner, A. M.; Autenrieth, T. J.; Nedashkivska, V.; Efremov, A. N.; Blattner, C.; Bastmeyer, M.; Levkin, P. A.
    2015. Nano letters, 15 (10), 7146–7154. doi:10.1021/acs.nanolett.5b03359Full textFull text of the publication as PDF document
  18. Stereoselective synthesis of highly functionalized hydroindoles as building blocks for rostratins B-D and synthesis of the pentacyclic core of rostratin C.
    Zhong, S.; Sauter, P. F.; Nieger, M.; Bräse, S.
    2015. Chemistry - a European journal, 21, 11219–11225. doi:10.1002/chem.201501199
  19. Secretome analysis identifies novel signal peptide peptidase-like 3 (Sppl3) substrates and reveals a role of Sppl3 in multiple golgi glycosylation pathways.
    Kuhn, P. H.; Voss, M.; Haug-Kröper, M.; Schröder, B.; Schepers, U.; Bräse, S.; Haass, C.; Lichtenthaler, S. F.; Fluhrer, R.
    2015. Molecular & cellular proteomics, 14 (6), 1584–1598. doi:10.1074/mcp.M115.048298
  20. Photophysical properties and synthesis of new dye-cyclooctyne conjugates for multicolor and advanced microscopy.
    Hörner, A.; Hagendorn, T.; Schepers, U.; Bräse, S.
    2015. Bioconjugate chemistry, 26 (4), 718–724. doi:10.1021/acs.bioconjchem.5b00059
  21. Ruthenium-catalyzed C-H activation of thioxanthones.
    Wagner, D.; Bräse, S.
    2015. Beilstein journal of organic chemistry, 11, 431–435. doi:10.3762/bjoc.11.49Full textFull text of the publication as PDF document
  22. Open source life science automation: Design of experiments and data acquisition via ’dial-a-device’.
    Lütjohann, D. S.; Jung, N.; Bräse, S.
    2015. Chemometrics and intelligent laboratory systems, 144, 100–107. doi:10.1016/j.chemolab.2015.04.002
  23. Structural studies and anticancer activity of a novel class of β-peptides.
    Kudryavtsev, K. V.; Yu, C. C.; Ivantcova, P. M.; Polshakov, V. I.; Churakov, A. V.; Bräse, S.; Zefirov, N. S.; Guh, J. H.
    2015. Chemistry, 10 (2), 383–389. doi:10.1002/asia.201403171
  24. Solid phase synthesis of functionalized indazoles using triazenes-scope and limitations.
    Garcia, A. M.; Jung, N.; Gil, C.; Nieger, M.; Bräse, S.
    2015. RSC Advances, 5 (80), 65540–65545. doi:10.1039/C5RA09705C
  25. From iridium and platinum to copper and carbon: New avenues for more sustainability in organic light-emitting diodes.
    Volz, D.; Wallesch, M.; Flechon, C.; Danz, M.; Verma, A.; Navarro, J. M.; Zink, D. M.; Bräse, S.; Baumann, T.
    2015. Green chemistry, 17, 1988–2011. doi:10.1039/C4GC02195A
  26. Functionalized triazolopeptoids-a novel class for mitochondrial targeted delivery.
    Althuon, D.; Rönicke, F.; Fürniss, D.; Quan, J.; Wellhöfer, I.; Jung, N.; Schepers, U.; Bräse, S.
    2015. Organic & biomolecular chemistry, 13, 4226–4230. doi:10.1039/C5OB00250H
  27. Application of a novel small scale UV LED photochemical batch reactor for the thiol-yne reaction.
    Griebenow, N.; Bräse, S.; Dilmac, A. M.
    2015. RSC Advances, 5 (67), 54301–54303. doi:10.1039/C5RA08787B
  28. Metal-free radical perfluoroalkylation of (hetero)arenes.
    Zhong, S.; Hafner, A.; Hussal, C.; Nieger, M.; Bräse, S.
    2015. RSC Advances, 5, 6255–6258. doi:10.1039/C4RA13430C
  29. Ring-closing metathesis of Co₂(CO)₆-alkyne complexes for the synthesis of 11-membered dienediynes: Overcoming thermodynamic barriers.
    Danilkina, N. A.; Lyapunova, A. G.; Khlebnikov, A. F.; Starova, G. L.; Bräse, S.; Balova, I. A.
    2015. The journal of organic chemistry, 80 (11), 5546–5555. doi:10.1021/acs.joc.5b00409
  30. Highly efficient synthesis of polyfluorinated dendrons suitable for click chemistry.
    Kölmel, D. K.; Nieger, M.; Bräse, S.
    2015. RSC Advances, 5 (46), 36762–36765. doi:10.1039/C5RA02804C
  31. Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6.
    Volz, Y.; Koschut, D.; Matzke-Ogi, A.; Dietz, M. S.; Karathanasis, C.; Richert, L.; Wagner, M. G.; Mély, Y.; Heilemann, M.; Niemann, H. H.; Orian-Rousseau, V.
    2015. Bioscience reports, 35 (4), e00236. doi:10.1042/BSR20150093Full textFull text of the publication as PDF document
  32. Reversible and rewritable surface functionalization and patterning via photodynamic disulfide Exchange.
    Du, X.; Li, J.; Welle, A.; Li, L.; Feng, W.; Levkin, P. A.
    2015. Advanced materials, 27 (34), 4997–5001. doi:10.1002/adma.201501177Full textFull text of the publication as PDF document
  33. Droplet-array (DA) sandwich chip: A versatile platform for High-Throughput Cell Screening based on superhydrophobic-superhydrophilic micropatterning.
    Popova, A. A.; Schillo, S. M.; Demir, K.; Ueda, E.; Nesterov-Mueller, A.; Levkin, P. A.
    2015. Advanced Materials, 27, 5217–5222. doi:10.1002/adma.201502115Full textFull text of the publication as PDF document
  34. Photoswitching in nanoporous, crystalline solids: An experimental and theoretical study for azobenzene linkers incorporated in MOFs.
    Wang, Z.; Heinke, L.; Jelic, J.; Cakici, M.; Dommaschk, M.; Maurer, R. J.; Oberhofer, H.; Grosjean, S.; Herges, R.; Bräse, S.; Reuter, K.; Wöll, C.
    2015. Physical chemistry, chemical physics, 17 (22), 14582–14587. doi:10.1039/c5cp01372kFull textFull text of the publication as PDF document
  35. CD44 Plays a Functional Role in Helicobacter pylori-induced Epithelial Cell Proliferation.
    Bertaux-Skeirik, N.; Feng, R.; Schumacher, M. A.; Li, J.; Mahe, M. M.; Engevik, A. C.; Javier, J. E.; Peek, R. M.; Ottemann, K.; Orian-Rousseau, V.; Boivin, G. P.; Helmrath, M. A.; Zavros, Y.
    2015. PLoS pathogens, 11 (2), 1–24/e1004663. doi:10.1371/journal.ppat.1004663Full textFull text of the publication as PDF document
  36. Paracrine met signaling triggers epithelial mesenchymal transition in mammary luminal progenitors, affecting their fate.
    Di-Cicco, A.; Petit, V.; Chiche, A.; Bresson, L.; Romagnoli, M.; Orian-Rousseau, V.; Vivanco, M.; Medina, D.; Faraldo, M. M.; Glukhova, M. A.; Deugnier, M. A.
    2015. eLife, 4, e06104/1–25. doi:10.7554/eLife.06104Full textFull text of the publication as PDF document
  37. Perspectives of CD44 targeting therapies.
    Orian-Rousseau, V.; Ponta, H.
    2015. Archives of toxicology, 89 (1), 3–14. doi:10.1007/s00204-014-1424-2
  38. Hierarchically functionalized magnetic core/multishell particles and their postsynthetic conversion to polymer capsules.
    Schmitt, S.; Silvestre, M.; Tsotsalas, M.; Winkler, A. L.; Shahnas, A.; Grosjean, S.; Laye, F.; Gliemann, H.; Lahann, J.; Bräse, S.; Franzreb, M.; Wöll, C.
    2015. ACS nano, 9, 4219–4226. doi:10.1021/acsnano.5b00483
  39. UV-induced tetrazole-thiol reaction for polymer conjugation and surface functionalization.
    Feng, W.; Li, L.; Yang, C.; Welle, A.; Trapp, O.; Levkin, P. A.
    2015. Angewandte Chemie / International edition, 54 (30), 8732–8735. doi:10.1002/anie.201502954Full textFull text of the publication as PDF document
  40. Reactive superhydrophobic surface and its photoinduced disulfide-ene and thiol-ene (bio)functionalization.
    Li, J.; Li, L.; Du, X.; Feng, W.; Welle, A.; Trapp, O.; Grunze, M.; Hirtz, M.; Levkin, P. A.
    2015. Nano letters, 15, 675–681. doi:10.1021/nl5041836
  41. Degradation mechanisms of polyfluorene-based organic semiconductor lasers under ambient and oxygen-free conditions.
    Brenner, P.; Fleig, L. M.; Liu, X.; Welle, A.; Bräse, S.; Lemmer, U.
    2015. Journal of polymer science / B, 53, 1029–1034. doi:10.1002/polb.23733
  42. Dual-color dual-focus line-scanning FCS for quantitative analysis of receptor-ligand interactions in living specimens.
    Dörlich, R. M.; Chen, Q.; Hedde, P. N.; Schuster, V.; Hippler, M.; Wesslowski, J.; Davidson, G.; Nienhaus, G. U.
    2015. Scientific Reports, 5, 10149. doi:10.1038/srep10149Full textFull text of the publication as PDF document
  43. Dual-stimuli-responsive microparticles.
    Sokolovskaya, E.; Rahmani, S.; Misra, A. C.; Bräse, S.; Lahann, J.
    2015. ACS applied materials & interfaces, 7, 9744–9751. doi:10.1021/acsami.5b01592
  44. The Diels-Alder approach to Δ⁹-tetrahydrocannabinol derivatives.
    Gläser, F.; Bröhmer, M. C.; Hurrle, T.; Nieger, M.; Bräse, S.
    2015. European Journal of Organic Chemistry, 2015 (7), 1516–1524. doi:10.1002/ejoc.201403379
  45. Planar-chiral building blocks for metal-organic frameworks.
    Cakici, M.; Gu, Z. G.; Nieger, M.; Bürck, J.; Heinke, L.; Bräse, S.
    2015. Chemical communications, 51 (23), 4796–4798. doi:10.1039/C5CC00694E
  46. Unprecedented pseudo-ortho and ortho metallation of [2.2]paracyclophanes - A methyl group matters.
    Enders, M.; Friedmann, C. J.; Plessow, P. N.; Bihlmeier, A.; Nieger, M.; Klopper, W.; Bräse, S.
    2015. Chemical communications, 51 (23), 4793–4795. doi:10.1039/C5CC00492F
  47. Bridging the efficiency gap: Fully bridged dinuclear Cu(I)-complexes for singlet harvesting in high-efficiency OLEDs.
    Volz, D.; Chen, Y.; Wallesch, M.; Liu, R.; Flechon, C.; Zink, D. M.; Friedrichs, J.; Flügge, H.; Steininger, R.; Göttlicher, J.; Heske, C.; Weinhardt, L.; Bräse, S.; So, F.; Baumann, T.
    2015. Advanced materials, 27, 2538–2543. doi:10.1002/adma.201405897
  48. Sulfur-based hyper cross-linked polymers.
    Monnereau, L.; Grandclaudon, C.; Muller, T.; Bräse, S.
    2015. RSC Advances, 5 (30), 23152–23159. doi:10.1039/C5RA01463H
  49. CD44 acts as a signaling platform controlling tumor progression and metastasis.
    Orian-Rousseau, V.
    2015. Frontiers in immunology, 6 (154), 1–4. doi:10.3389/fimmu.2015.00154Full textFull text of the publication as PDF document
  50. CD44 functions in Wnt signaling by regulating LRP6 localization and activation.
    Schmitt, M.; Metzger, M.; Gradl, D.; Davidson, G.; Orian-Rousseau, V.
    2015. Cell death and differentiation, 22, 677–689. doi:10.1038/cdd.2014.156
  51. Synthesis of highly functionalized C₆₀ fullerene derivatives and their applications in material and life sciences.
    Yan, W.; Seifermann, S. M.; Pierrat, P.; Bräse, S.
    2015. Organic and Biomolecular Chemistry, 13 (1), 25–54. doi:10.1039/C4OB01663GFull textFull text of the publication as PDF document
  52. Xanthone dimers: a compound family which is both common and privileged.
    Wezeman, T.; Bräse, S.; Masters, K.-S.
    2015. Natural Product Reports, 32 (1), 6–28. doi:10.1039/C4NP00050AFull textFull text of the publication as PDF document